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CAS NUMBER: 75-05-8
EC NUMBER: 200-835-2
MOLECULAR FORMULA: CH3CN
MOLECULAR WEIGHT: 41.05
Acetonitrile HPLC is widely employed as a solvent in various studies and has high dielectric constant.
Acetonitrile HPLC has a role as a polar aprotic solvent and an inhibitor.
Acetonitrile HPLC is an aliphatic nitrile and a volatile organic compound.
Acetonitrile HPLC has many uses, including as a solvent, for spinning fibers, and in lithium batteries.
Acetonitrile HPLC is primarily found in air from automobile exhaust and manufacturing facilities.
Acetonitrile HPLC is the chemical compound with the formula CH3CN.
Acetonitrile HPLC is the simplest organic nitrile.
Acetonitrile HPLC is produced mainly as a byproduct of acrylonitrile manufacture.
Acetonitrile HPLC is used as a polar aprotic solvent in organic synthesis and in the purification of butadiene.
Acetonitrile HPLC is the chemical compound with the formula CH3CN.
Acetonitrile HPLC is the simplest organic nitrile (hydrogen cyanide is a simpler nitrile, but the cyanide anion is not classed as organic).
Acetonitrile HPLC is produced mainly as a byproduct of acrylonitrile manufacture.
Acetonitrile HPLC is used as a polar aprotic solvent in organic synthesis and in the purification of butadiene.
Acetonitrile HPLC is an extremely dangerous substance and must be handled with caution as it can cause severe health effects.
Acetonitrile HPLC is also known as cyanomethane, ethyl nitrile, ethanenitrile, methanecarbonitrile, acetronitrile cluster and methyl cyanide.
Acetonitrile HPLC is easily ignited by heat, sparks or flames and gives off highly toxic hydrogen cyanide fumes when heated.
Acetonitrile HPLC dissolves easily in water.
Acetonitrile HPLC may be used as an extraction solvent during the quantification of pesticide residues in fruits and vegetables.
Acetonitrile HPLC is a high-purity solvent for use in analytical and preparative separations.
Acetonitrile HPLC for use in high performance liquid chromatography (HPLC).
Acetonitrile HPLC is packaged in four 4L amber glass bottles to protect the integrity of the solvent from UV light.
Acetonitrile HPLC is by far the preferred organic solvent for use in Reversed Phase High Performance Liquid Chromatography (RP-HPLC) today, owing to an excellent combination of physical properties of this solvent that are favorable for chromatography (viscosity, UV absorbance cutoff, boiling point).
In recent years, improvements in both instrument and stationary phase technologies have greatly enhanced the performance of routine laboratory HPLC, leading to an excess of performance for many users.
Acetonitrile HPLC is manufactured at our highly advanced processing unit by taking finest quality chemical compounds.
Acetonitrile HPLC is well processed as per the set industry norms and highly demanded by the number of clients as a solvent.
Possibilities for production are nucleophilic substitution reactions of e.g. bromomethane with sodium cyanide (NaCN).
Industrially, Acetonitrile HPLC is produced in relatively small quantities as a by-product in the manufacture of acrylonitrile.
When heated to high temperatures and in the event of fire, Acetonitrile HPLC gives off toxic gases such as hydrogen cyanide and nitrogen oxides.
Explosive mixtures are formed with air.
Acetonitrile HPLC attacks rubber and dissolves many polymers.
When in contact with sulfuric acid under heat, explosive polymerization may occur.
Acetonitrile HPLC forms with water an azeotropic mixture of 83.7 wt.% acetonitrile to 16.3 wt.% water and a boiling point of 76.5 °C, 5.5 K below the boiling point of pure acetonitrile.
Acetonitrile HPLC forms highly flammable vapor-air mixtures.
Acetonitrile HPLC has a flash point at 2 °C.
The explosion range is between 3.0% by volume (50 g/m3) as the lower explosion limit (LEL) and 17% by volume as the upper explosion limit.
The limiting oxygen concentration is 12.7 vol% at 25 °C.
Acetonitrile HPLC is a common solvent in the laboratory, in chemical analysis (e.g. HPLC) and in technical chemistry, mainly for the extraction of 1,3-butadiene.
Acetonitrile HPLC is used as a solvent for conducting salts in double-layer capacitors.
Acetonitrile HPLC is an irritant.
Acetonitrile HPLC is harmful by inhalation, ingestion and skin contact.
Acetonitrile HPLC is absorbed through the skin (percutaneously) and acts as a blood poison in the body.
Acetonitrile HPLC exhibits low toxicity at low doses.
Acetonitrile HPLC is metabolized to hydrogen cyanide, which is the cause of the observed symptoms.
Acetonitrile HPLC is for further commercial manufacturing, laboratory or research use, and may be used as an excipient or a process solvent for pharmaceutical purposes.
Acetonitrile HPLC is not intended for use as an active ingredient in drug manufacturing nor as a medical device or disinfectant.
Appropriate use of Acetonitrile HPLC is the responsibility of the user.
Acetonitrile HPLC is a colorless liquid used in chemical laboratories as a polar aprotic solvent in organic synthesis, as well as a carrier (mobile phase) solvent in high pressure liquid chromatography (HPLC).
Acetonitrile HPLC is the most commonly used organic mobile phase component due to its unique properties that set it apart from the other LC solvents (midrange solvent strength, excellent solvent performance, generation of well-defined chromatographic peaks, and lower viscosity and lower UV cutoff compared to alcohols and ethers.
Acetonitrile HPLC is typically a by-product of the large-scale production of acrylonitrile (from ammonia and propylene) and may contain a wide range of very low-level impurities, including acrylonitrile, α(β)-methacrylonitrile, cis/trans butenenitrile, acetaldehyde, acetone, methanol, ethyl cyanide, acrolein, allyl alcohol, propenoic acid, oxazol, and acetic acid.
Trace amounts of the above impurities may remain in HPLC acetonitrile even after a sophisticated purification process.
Some of these trace impurities not only can lead to high baseline and ghost peaks, interfering with the qualification and quantification of analytes, but can also contaminate the column and block the system, resulting in malfunction of the instrument.
Acetonitrile HPLC is a medium-polarity solvent with a convenient liquid range that is miscible with water and makes it one of the most popular HPLC solvent choices.
Acetonitrile HPLC is used as a solvent in HPLC to retain or elute chemical species of interest from a stationary phase.
Acetonitrile HPLC may also be used as a needle or injection port wash solution.
Acetonitrile HPLC the basic principles follow the “like dissolves like" idea where molecules of interest are retained and eluted off of an HPLC column using static (isocratic) or variable (graident) mixtures of solvents with different polarities.
Commonly, Acetonitrile HPLC is used as a polar solvent and acetonitrile used as a non-polar solvent.
Acetonitrile HPLC is the chemical compound with the formula CH3CN.
Acetonitrile HPLC is the simplest organic nitrile (hydrogen cyanide is a simpler nitrile, but the cyanide anion is not classed as organic).
Acetonitrile HPLC is produced mainly as a byproduct of acrylonitrile manufacture.
Acetonitrile HPLC is used as a polar aprotic solvent in organic synthesis and in the purification of butadiene.
The N≡C−C skeleton is linear with a short C≡N distance of 1.16 Å.
Acetonitrile HPLC is used mainly as a solvent in the purification of butadiene in refineries.
Acetonitrile HPLC is fed into the top of a distillation column filled with hydrocarbons including butadiene, and as the acetonitrile falls down through the column, it absorbs the butadiene which is then sent from the bottom of the tower to a second separating tower.
Acetonitrile HPLC is used as a medium-polarity solvent that is miscible with water and a range of organic solvents, but not saturated hydrocarbons.
Acetonitrile HPLC has a convenient liquid range and a high dielectric constant of 38.8. With a dipole moment of 3.92 D, acetonitrile dissolves a wide range of ionic and nonpolar compounds and is useful as a mobile phase in HPLC and LC–MS.
Acetonitrile HPLC is widely used in battery applications because of its relatively high dielectric constant and ability to dissolve electrolytes.
For similar reasons Acetonitrile HPLC is a popular solvent in cyclic voltammetry.
Acetonitrile HPLCs ultraviolet transparency UV cutoff, low viscosity and low chemical reactivity make it a popular choice for high-performance liquid chromatography (HPLC).
Acetonitrile HPLC plays a significant role as the dominant solvent used in the manufacture of DNA oligonucleotides from monomers.
Acetonitrile HPLC it is used as a solvent for the manufacture of pharmaceuticals and photographic film.
Acetonitrile HPLC is used mainly as a solvent in the purification of butadiene in refineries.
Acetonitrile HPLC is fed into the top of a distillation column filled with hydrocarbons including butadiene, and as the acetonitrile falls down through the column, it absorbs the butadiene which is then sent from the bottom of the tower to a second separating tower.
Acetonitrile HPLC is used as a medium-polarity solvent that is miscible with water and a range of organic solvents, but not saturated hydrocarbons.
Acetonitrile HPLC has a convenient liquid range and a high dielectric constant of 38.8. With a dipole moment of 3.92 D, acetonitrile dissolves a wide range of ionic and nonpolar compounds and is useful as a mobile phase in HPLC and LC–MS.
Acetonitrile HPLC is widely used in battery applications because of its relatively high dielectric constant and ability to dissolve electrolytes.
Acetonitrile HPLC is a popular solvent in cyclic voltammetry.
Acetonitrile HPLCs ultraviolet transparency UV cutoff, low viscosity and low chemical reactivity make it a popular choice for high-performance liquid chromatography (HPLC).
Acetonitrile HPLC plays a significant role as the dominant solvent used in the manufacture of DNA oligonucleotides from monomers.
Acetonitrile HPLC is used as a solvent for the manufacture of pharmaceuticals and photographic film.
Acetonitrile HPLC is a common two-carbon building block in organic synthesis of many useful chemicals, including acetamidine hydrochloride, thiamine, and α-napthaleneacetic acid.
Acetonitrile HPLCs reaction with cyanogen chloride affords malononitrile.
Acetonitrile HPLC has a free electron pair at the nitrogen atom, which can form many transition metal nitrile complexes.
Being weakly basic, Acetonitrile HPLC is an easily displaceable ligand.
Acetonitrile HPLC is a byproduct from the manufacture of acrylonitrile.
Most is combusted to support the intended process but an estimated several thousand tons are retained for the above-mentioned applications.
Production trends for Acetonitrile HPLC thus generally follow those of acrylonitrile.
Acetonitrile HPLC appears as a colorless limpid liquid with an aromatic odor.
Flash point is 42°F.
Density is 0.783 g / cm3.
Acetonitrile HPLC is a nitrile that is hydrogen cyanide in which the hydrogen has been replaced by a methyl group.
Acetonitrile HPLC can react with water, steam or acids to produce flammable vapors that can form explosive mixtures when exposed to air.
The vapors are heavier than air and can travel to low or confined areas.
Acetonitrile HPLC is used to make pharmaceuticals, perfumes, rubber products, pesticides, acrylic nail removers and batteries.
Acetonitrile HPLC is also used to extract fatty acids from animal and vegetable oils.
Before working with acetonitrile, employee training should be provided on safe handling and storage procedures.
BENEFITS:
-Time and cost savings through quality-related high reproducibility of the analysis results
-Documented UV suitability, also suitable for fluorescence detection and MS detection
-Optimal peak baseline separation
-High resolution and sensitivity in LC-MS
-Trouble-free baseline for better reproducibility
FEATURES:
– For analytical and preparative separation
– Mobile phase in PHLC or LC technique including gel permeation chromatography
– Mobile phase for different type of detector
– Use in the wavelength between 230-190 nm (Far UV region)
– For isocratic technique: low UV absorption
FEATURES:
-Best for mobile phase in HPLC
-Low viscosity
-Accurate composition
PHYSICAL AND CHEMICAL PROPERTIES:
-Boiling point: 81.6 °C (1013 hPa)
-Density: 0.78 g/cm3 (20 °C)
-Explosion limit: 3.0 - 17 %(V)
-Flash point: 2 °C
-Ignition temperature: 524 °C
-Melting Point: -45.7 °C
-Vapor pressure: 98.64 hPa (20 °C)
PROPERTIES:
-Quality Level: 100
-vapor density: 1.41 (vs air)
-vapor pressure: 72.8 mmHg ( 20 °C)
-form: liquid
-autoignition temp.: 973 °F
-expl. lim.: 16 %
SPECIFICATION:
-Purity (GC): ≥ 99.9 %
-Identity (IR): conforms
-Evaporation residue: ≤ 2.0 mg/l
-Water: ≤ 0.02 %
-Color: ≤ 10 Hazen
-Density (d 20 °C/20 °C): 0.78
-Refractive index (n 20/D): 1.344
-Boiling range (80-82°C): ≥ 95 % (v/v)
-Acidity: ≤ 0.0002 meq/g
STORAGE:
Store at +2°C to +30°C.
SYNONYM:
Ethanenitrile
Ethyl nitrile
Methanecarbonitrile
Methane, cyano-
Acetonitril
Cyanure de methyl
Methylkyanid
Methylkyanid
USAF EK-488
RCRA waste number U003
Cyanure de methyl
Acetonitril
CH3CN
NCI-C60822
NCMe
Acetonitrile, dimer
UNII-Z072SB282N
Acetonitrile, anhydrous
CHEBI:38472
Z072SB282N
