GEKSAGIDRAT KHLORIDA ALYUMINIYA

GEKSAGIDRAT KHLORIDA ALYUMINIYA

CAS-№ : 7784-13-6

Geksagidrat khlorida alyuminiya - eto antiperspirant, kotoryy vozdeystvuyet na kletki, proizvodyashchiye pot. Geksagidrat khlorida alyuminiya dlya mestnogo primeneniya (dlya kozhi) ispol'zuyetsya dlya lecheniya chrezmernogo potootdeleniya, takzhe nazyvayemogo gipergidrozom. Geksagidrat khlorida alyuminiya takzhe mozhet ispol'zovat'sya dlya tseley, ne ukazannykh v dannom rukovodstve.

SINONIMY: GEKSAGIDRAT KHLORIDA ALYUMINIYA; Aluminum chloride hexahydrate; aluminium chloride hexahydrate; Drysol; Aluminum trichloride; hexahydrate; Xerac AC; AlCl3.6H2O; CCRIS 5552; aluminium trichloride hexahydrate; Aluminum(III) chloride, hexahydrate; ALUMINUM CHLORIDE, HEXAHYDRATE; AI3-01918; Aluminum chloride (USP); Aluminum chloride [USP]; Lumicain (TN); CHEMBL3833314; CHEBI:30115; aluminium chloride--water (1/6); aluminium(III) chloride hexahydrate; 5468AF; AKOS015902485; Aluminum chloride, 0.5M aqueous solution; LS-16465; Aluminum chloride hexahydrate, puriss., 99.5%; D02845; Aluminum chloride hexahydrate, ReagentPlus(R), 99%; Q27094303; Aluminum chloride hexahydrate, 99.98% trace metals grade; Aluminum chloride hexahydrate, JIS special grade, >=98.0%; Aluminum chloride hexahydrate, SAJ first grade, >=97.0%; Aluminum chloride hexahydrate, tested according to Ph.Eur.; Aluminum chloride hexahydrate, Vetec(TM) reagent grade, 98%; Aluminum chloride hexahydrate, meets EP, BP, USP testing specifications; Aluminum chloride hexahydrate, puriss., meets analytical specification of Ph. Eur., BP, USP, 97.0-101.0%

Formula veshchestva: AlCl3 · 6H2O
Molekulyarnyy ves: 241,43 g / mol'
CAS-№ : 7784-13-6
EC-No. : 231-208-1

SIMVOLY
Vneshniy vid: Belyy ili slegka zheltovatyy kristallicheskiy poroshok ili bestsvetnyye kristally, rasplyvayushchiyesya na vozdukhe.
Rastvorimost': khorosho rastvorim v vode, svobodno rastvorim v etanole (96 protsentov), rastvorim v glitserine.
IDENTIFIKATSIYA
A. Razvedite 0,1 ml rastvora S2 (sm. Testy) do 2 ml vodoy. Rastvor dayet reaktsiyu khloridov.
B. Razvesti 0,3 ml rastvora S2 do 2 ml vodoy. Rastvor dayet reaktsiyu alyuminiya.
TESTY
Rastvor S1: rastvorit' 10,0 g v distillirovannoy vode i dovesti do 100 ml tem zhe rastvoritelem.
Rastvor S2: Razvedite 50 ml rastvora S1 do 100 ml vodoy.
Vneshniy vid rastvora: Rastvor S2 prozrachnyy i ne boleye intensivno okrashen, chem rastvor sravneniya.
Sul'faty: maksimum 100 chastey na million, opredeleno v rastvore S1.
Zhelezo: maksimum 10 chastey na million, opredeleno v rastvore S1.
Shchelochnyye i shchelochno-zemel'nyye metally: ne boleye 0,5%.
Tyazhelyye metally: maksimum 20 chastey na million.
Voda: ot 42,0% do 48,0%, pri opredelenii po 50,0 mg.
ANALIZ
Rastvorit' 0,500 g v 25,0 ml vody. Provedite kompleksometricheskoye titrovaniye alyuminiya. Titrovat' 0,1 M sul'fatom tsinka do tekh por, poka tsvet indikatora ne izmenitsya s sero-zelenogo na rozovyy. Provedite kholostoye titrovaniye. 1 ml 0,1 M natriya edta ekvivalenten 24,14 mg AlCl3,6H2O.
________________________________________
Khlorid alyuminiya, klass USP
AlCl3 · 6H2O - 241,43 - [7784-13-6].
Khlorid alyuminiya soderzhit ne meneye 95,0% i ne boleye 102,0% AlCl3 v pereschete na bezvodnyy.
Identifikatsiya: rastvor (1 iz 10) sootvetstvuyet testam na alyuminiy i khloridy.
Voda: ot 42,0% do 48,0%.
Sul'fat: dobavleniye 0,2 ml khlorida bariya k 10 ml rastvora (1 iz 100) ne vyzyvayet pomutneniya v techeniye 1 minuty.
Predel shchelochnykh i shchelochnozemel'nykh metallov: predel 0,5%.
Tyazhelyye metally: predel 0,002%.
Zhelezo: predel 0,001%.

Fizicheskiye svoystva

Belyy ili zheltovatyy rasplyvayushchiysya poroshok; slabyy zapakh HCl; plotnost' 2,40 g / sm3; rastvorim v vode i polyarnykh organicheskikh rastvoritelyakh, takikh kak spirt; vodnyy rastvor kislyy.

Ispol'zuyet

Geksagidrat khlorida alyuminiya ispol'zuyetsya pri prigotovlenii dezodorantov i antiperspirantov. Krome togo, on primenyayetsya pri otdelke tekstilya dlya uluchsheniya antistaticheskikh kharakteristik i pokazateley vosplamenyayemosti razlichnykh tekstil'nykh materialov. Kommercheski on prodayetsya v vide kristallicheskogo poroshka ili 28% rastvora v vode.

Podgotovka

Geksagidrat khlorida alyuminiya poluchayut rastvoreniyem Al (OH) 3 v konts. HCl i propuskaniye gazoobraznogo HCl cherez rastvor pri 0 ° C. Osadok promyvayut dietilovym efirom i sushat. Krome togo, yego poluchayut gidrolizom bezvodnogo AlCl3 v kholodnoy razbavlennoy HCl.

Reaktsii

Razlagayetsya na oksid alyuminiya pri nagrevanii do 300 ° C;
2AlCl3 • 6H2O → 2Al2O3 + 6HCl + 9H2O
Reagiruyet s rastvorom kausticheskoy sody s obrazovaniyem geleobraznogo osadka gidroksida alyuminiya (vodnyy oksid alyuminiya); dayet odnoosnovnyy stearat alyuminiya, Al (OH) 2 [OOC (CH2) 16CH3], kogda yego rastvor smeshivayut s rastvorom stearata natriya.

Khimicheskiye svoystva

Kristallicheskoye tverdoye veshchestvo ot belogo do bledno-zheltogo tsveta

Ispol'zuyet

Bezvodnaya forma, podkhodyashchaya v kachestve kislotnogo katalizatora, osobenno v reaktsiyakh tipa Fridelya-Kraftsa; pri krekinge nefti; v proizvodstve kauchukov, smazochnykh materialov. Forma geksagidrata, ispol'zuyemaya dlya konservirovaniya drevesiny; dezinfektsiya konyushen, boyni i t.d .; v dezodorantakh i antiperspirantnykh preparatakh; pererabotka syroy nefti; krasheniye tkaney; proizvodstvo pergamentnoy bumagi. V konservatsii drevesiny, dezinfektsii khlevov i t. D .; v dezodorantakh i antiperspirantnykh preparatakh; pri pererabotke syroy nefti i krashenii tkaney; v stomatologicheskoy keramike; v vyazhushchikh sredstvakh dlya mestnogo primeneniya

Pokazaniya

Geksagidrat khlorida alyuminiya (6,25% Xerac A-C) - effektivnyy antiperspirant, obladayushchiy takzhe antibakterial'nym deystviyem. Eto mozhet byt' polezno v sluchayakh ugrevoy sypi, pri kotorykh potootdeleniye zametno ili, po-vidimomu, usugublyayet bolezn', no yego effekty nedostatochno izucheny.

Geksagidrat khlorida alyuminiya reagiruyet s vodoy s obrazovaniyem solyanoy kisloty. Poetomu pered naneseniyem obrabatyvayemyye uchastki dolzhny byt' polnost'yu vysusheny, chtoby izbezhat' ozhoga kozhi.
Primeneniye dolzhno byt' ogranicheno tol'ko porazhennymi uchastkami.
Driklor ne sleduyet nanosit' na kozhu, kotoraya byla vybrita v techeniye 12 chasov, povrezhdena ili razdrazhena.
Produkty dlya udaleniya volos nel'zya ispol'zovat' na obrabatyvayemykh uchastkakh v techeniye 12 chasov do ili posle naneseniya Driklora.
Izbegayte kontakta s glazami, nozdryami, rtom ili drugimi slizistymi obolochkami. Pri sluchaynom popadanii v glaza ili na drugiye slizistyye obolochki khorosho promyt' vodoy.

Mekhanizm deystviya
Geksagidrat khlorida alyuminiya yavlyayetsya kislym i, kak schitayetsya, deystvuyet putem diffuzii v potovyye protoki, gde pri neytralizatsii obrazuyet geleobraznyye gidroksidy, prepyatstvuyushchiye potoku pota.
Antiperspirantnyy effekt geksagidrata khlorida alyuminiya chastichno ob"yasnyayetsya proizvodstvom mekhanicheskoy blokirovki v ekkrinnom protoke. Posle naneseniya alyuminiy obnaruzhivayetsya v rogovom sloye i vnutri prosveta v kontsevom kanale.
Bylo vyskazano predpolozheniye, chto iony metallov obrazuyut osazhdayushchiye kompleksy s mukopolisakharidami i karboksil'nymi gruppami rogovogo sloya. Eto vyzyvayet povrezhdeniye epitelial'nykh kletok prosveta, obrazuya obstruktivnyy konglomerat, kotoryy zakuporivayet akrosiringium. Issledovaniya dlitel'nogo lecheniya khloridom alyuminiya pokazali, chto dlitel'noye primeneniye privodit k funktsional'noy i strukturnoy degeneratsii ekkrinnykh atsinusov, chto ob"yasnyayet nablyudayemoye progressivnoye umen'sheniye tyazhesti gipergidroza vo vremya lecheniya.