EMPICOL 0585 A

EMPICOL 0585 A

CAS No. : 126-92-1
EC No. : 204-812-8

Synonyms:
EMPICOL® 0585 / A; Sodium Ethylhexyl Sulfate; sodium 2-ethylhexyl sulfate; SODIUM 2-ETHYLHEXYL SULFATE; Sodium ethasulfate; 126-92-1; Sodium etasulfate; Sipex bos; NIA proof 08; Emersal 6465; Pentrone ON; Ethasulfate sodium; Sulfirol 8; 08-Union carbide; Tergitol 08; 2-Ethylhexylsulfate sodium; Sodium octyl sulfate, iso; Tergitol anionic 08; Propaste 6708; Sodium Ethasulfate [USAN]; Sulfuric acid, mono(2-ethylhexyl) ester, sodium salt; Sole Tege TS-25; Sodium (2-ethylhexyl)alcohol sulfate; Emcol D 5-10; HSDB 1314; Sodium mono(2-ethylhexyl) sulfate; 2-Ethylhexyl sodium sulfate; Etasulfate de sodium [INN-French]; NSC 4744; EINECS 204-812-8; Mono(2-ethylhexyl)sulfate sodium salt; 2-Ethyl-1-hexanol sodium sulfate; NCI-C50204; Sodium(2-ethylhexyl)alcohol sulfate; 1-Hexanol, 2-ethyl-, sulfate, sodium salt; 2-Ethyl-1-hexanol sulfate sodium salt; Mono(2-ethylhexyl) sulfate sodium salt; Hexanol, 2-ethyl-, hydrogen sulfate, sodium salt; 1-Hexanol, 2-ethyl-, hydrogen sulfate, sodium salt; 2-Ethyl-1-hexanol hydrogen sulfate sodium salt; DSSTox_CID_6033; Sodium ethasulfate (USAN); Sulfuric acid, mono(2-ethylhexyl) ester, sodium salt (1:1); Natrii etasulfas; Etasulfato sodico; CAS-126-92-1; Etasulfate de sodium; 2-Ethylhexylsiran sodny; Niaproof(R); sodium etasul-fate; ACMC-1C2MQ; EC 204-812-8; SCHEMBL57666; 2-Ethylhexylsulphate,sodium salt; Empicol 0585 A; 2-Ethylhexyl sulfate sodium salt; Sodium (2-Ethy lhexyl)Alcohol Sulfate; Sodium 2-ethylhexyl sulfate, ~50% in H2O; Sodium 2-ethylhexyl sulfate, Type 8, ~40%; Sodium 2-ethylhexyl sulfate solution, 50% in water; EMPİCOL 0045/B; EMPICOL 0045/B; 0045/B; 5085 EMPICOL;EMPICOL-0045/B; empicol0045/B; empicol-0045/B; Empicol-0045/B; Empicol0045/B; Empicol 0045/B; SODIUM 2-ETHYLHEXYL SULFATE; Sodium ethasulfate; 126-92-1; Sodium etasulfate; Sipex bos; NIA proof 08; Emersal 6465; Pentrone ON; Ethasulfate sodium; Sulfirol 8; 08-Union carbide; Tergitol 08; 2-Ethylhexylsulfate sodium; Sodium octyl sulfate, iso; Tergitol anionic 08; Propaste 6708; Sodium Ethasulfate [USAN]; Sulfuric acid, mono(2-ethylhexyl) ester, sodium salt; Sole Tege TS-25; Sodium (2-ethylhexyl)alcohol sulfate; Emcol D 5-10; HSDB 1314; Sodium mono(2-ethylhexyl) sulfate; 2-Ethylhexyl sodium sulfate; Etasulfate de sodium [INN-French]; NSC 4744; EINECS 204-812-8; Mono(2-ethylhexyl)sulfate sodium salt; 2-Ethyl-1-hexanol sodium sulfate; EMPICOL 0585 A; Sodium(2-ethylhexyl)alcohol sulfate; 1-Hexanol, 2-ethyl-, sulfate, sodium salt; 2-Ethyl-1-hexanol sulfate sodium salt; Mono(2-ethylhexyl) sulfate sodium salt; Hexanol, 2-ethyl-, hydrogen sulfate, sodium salt; 1-Hexanol, 2-ethyl-, hydrogen sulfate, sodium salt; 2-Ethyl-1-hexanol hydrogen sulfate sodium salt; Sodium ethasulfate (USAN); Sulfuric acid, mono(2-ethylhexyl) ester, sodium salt (1:1); Natrii etasulfas; Etasulfato sodico; CAS-126-92-1; Etasulfate de sodium; 2-Ethylhexylsiran sodny; NCGC00164327-02; C8H17NaO4S; Niaproof(R); sodium etasul-fate; ACMC-1C2MQ; EC 204-812-8; SCHEMBL57666; 2-Ethylhexylsulphate,sodium salt; CHEMBL2107701; DTXSID1026033; 2-Ethylhexyl sulfate sodium salt; Sodium (2-Ethy lhexyl)Alcohol Sulfate; Sodium 2-ethylhexyl sulfate, ~50% in H2O; Sodium 2-ethylhexyl sulfate, Type 8, ~40%; Sodium 2-ethylhexyl sulfate solution, 50% in water; EMPICOL 0585 A; empicol0045/B; empicol-0045/B; Empicol-0045/B; Empicol0045/B;  1-Hexanol, 2-ethyl-, sulfate, sodium salt; 2-Ethyl-1-hexanol sulfate sodium salt; Mono(2-ethylhexyl) sulfate sodium salt; Hexanol, 2-ethyl-, hydrogen sulfate, sodium salt; 1-Hexanol, 2-ethyl-, hydrogen sulfate, sodium salt; 2-Ethyl-1-hexanol hydrogen sulfate sodium salt; DSSTox_CID_6033; Sodium ethasulfate (USAN); Sulfuric acid, mono(2-ethylhexyl) ester, sodium salt (1:1); Natrii etasulfas; Etasulfato sodico; CAS-126-92-1; Etasulfate de sodium; 2-Ethylhexylsiran sodny; NCGC00164327-02; C8H17NaO4S; Niaproof(R); sodium etasul-fate; ACMC-1C2MQ; EC 204-812-8; SCHEMBL57666; 2-Ethylhexylsulphate,sodium salt; CHEMBL2107701; DTXSID1026033; 2-Ethylhexyl sulfate sodium salt; Sodium (2-Ethy lhexyl)Alcohol Sulfate; Sodium 2-ethylhexyl sulfate, ~50% in H2O; Sodium 2-ethylhexyl sulfate, Type 8, ~40%; Sodium 2-ethylhexyl sulfate solution, 50% in water; EMPİCOL 0045/B; EMPICOL 0045/B; 0045/B; 5085 EMPICOL;EMPICOL-0045/B; empicol0045/B; empicol-0045/B; Empicol-0045/B; Empicol0045/B; Empicol 0045/B; SODIUM 2-ETHYLHEXYL SULFATE; Sodium ethasulfate; 126-92-1; Sodium etasulfate; Sipex bos; NIA proof 08; Emersal 6465; Pentrone ON; Ethasulfate sodium; Sulfirol 8; 08-Union carbide; Tergitol 08

Empicol 0585 A

EMPICOL 0585 A is an aqueous solution of sodium 2-ethylhexyl sulfate. This product is mainly used as a wetting agent.

Application
Sodium Empicol 0585 A is an anionic surfactant that can be used:
• In suspension polymerization.[1]
• In the analysis of phenolic compounds through microchip-CE with pulsed amperometric detection.[2]
• As charge balancing anions in the synthesis of organo-layered double hydroxides (organo-LDHs).

Empicol 0585 A is a clear, colorless, slightly viscous liquid. (NTP, 1992)
Empicol 0585 A is an indirect food additive for use only as a component of adhesives.

Chemical description    Sodium 2-ethylhexyl sulfate
INCI name    Sodium Ethylhexyl Sulfate
EC name    Sodium etasulfate
CAS #    126-92-1
EC #    204-812-8

Empicol 0585 A is a low-foaming anionic surfactant with excellent wetting properties and outstanding stability in highly electrolyte, alkaline and acidic systems. It is a profound hydrotropic and wetting agent suitable for use in the production of liquid detergents for household and industrial use such as hard-surface cleaners and alkaline and acid metal degreasers.
 
Owing to its wetting and penetrating properties Empicol 0585 A is used as a mercerizing agent in textile industry, in metal galvanization, pickling and brightening, in lye washing and peeling solutions for fruits and vegetables, in fountain solutions for offset printing, wallpaper removal solutions etc.

Physical and chemical properties
appearance at 20°C    clear yellowish liquid
density at 20°C, g/cm3, c.    1.10
active matter, % wt.    42 ± 2
pH, 3% aqueous solution    9.0 - 10.5

Application areas of Empicol 0585 A
HI&I cleaning
Emulsion polymerization
Metalworking
Textile auxiliaries
Printing industry
Agriculture

Find Empicol 0585 A ideal for agriculture applications. This surfactant and wetting agent works well in fruit and vegetable washes.

Product Groups of Empicol 0585 A
Anionic Surfactants
Sub Product Groups of Empicol 0585 A
Fatty Alcohol Sulfates
Function of Empicol 0585 A
Anionic Surfactants
Form of Delivery of Empicol 0585 A
Liquid
Chemical Description of Empicol 0585 A
2-Ethylhexyl sulfate, sodium salt

Application of Empicol 0585 A
Dishwashing
Hard Surface Cleaning
Food and Beverage Processing
Food Service and Kitchen Hygiene
Commercial Laundry
Institutional Cleaning and Sanitation
Vehicle and Transportation Care

Empicol 0585 A is a dried powder of sodium lauryl sulfate. It is a versatile surfactant capable of producing a fine, creamy foam. It is also a good emulsifier and an excellent wetting agent, with good electrolyte tolerance, making it ideal for use as the primary surfactant in a range of cosmetic and detergent applications, such as shaving creams, laundry detergents and additives and toilet blocks. It also finds application as an emulsifier, wetting and foaming agent in many other diverse markets.

Empicol 0585 A

Sodium Lauryl Sulfate. Acts as a surfactant and emulsifier. Exhibits high electrolyte tolerance, good emulsifying properties and creaminess. Used in shower and bath products, creams and lotions, shampoo and shaving products.
Claims    
Surfactants / Cleansing Agents > Anionics > Alkyl Sulfates
Emulsifiers
creaminess/rich feel
INCI Names    SODIUM LAURYL SULFATE
CAS Number    151-21-3

EMPICOL 0045/B
EMPICOL® 0045/B is a dried powder of sodium lauryl sulfate. It is a versatile surfactant capable of producing a fine, creamy foam. It is also a good emulsifier and an excellent wetting agent, with good electrolyte tolerance, making it ideal for use as the primary surfactant. *RSPO Mass Balance version available on request.

INGREDIENT IDENTIFICATION
Name
EMPICOL® 0045/B*
Segment
Personal care
INCI name
Sodium Lauryl Sulfate
IUPAC name
N/A
CAS numbers
151-21-3
GENERAL USE
Performance claims
N/A
Sustainability claims
Natural
Function
Cleansing agents, Denaturants, Emulsifiers, Foaming agents, Surfactants
Applications
Cleansers , Cosmetics ,Creams ,Foams ,Hair care ,Hair removal ,Shampoos ,Skin care

Empicol 0585 A is a dried powder of sodium lauryl sulfate. It is a versatile surfactant capable of producing a fine, creamy foam. It is also a good emulsifier and an excellent wetting agent, with good electrolyte tolerance, making it ideal for use as the primary surfactant in a range of cosmetic and detergent applications, such as shaving creams, laundry detergents and additives and toilet blocks. It also finds application as an emulsifier, wetting and foaming agent in many other diverse markets.

EMPICOL® AL 30/AV*
Ammonium Lauryl Sulfate
EO-free primary anionic surfactant providing rich lather. For use in cleansing products such as shampoos and body washes.

EMPICOL® AL 70*
Ammonium Lauryl Sulfate
EMPICOL® AL 70 is a highly active, aqueous solution of ammonium lauryl sulfate. It has excellent foaming characteristics and it can be used to promote the formation of a creamy and luxurious lather in a wide variety of cosmetic products, such as shampoos, bath and shower gels and liquid soaps.

EMPICOL® EAC 70*
Ammonium Laureth Sulfate
High active, primary anionic surfactant providing rich lather for use in cleansing products such as shampoos and body washes.

EMPICOL® EGC 70*
Magnesium Laureth Sulfate
High active, primary anionic surfactant providing rich lather for use in cleansing products such as shampoos and body washes.

EMPICOL® 0045/B*
Sodium Lauryl Sulfate
EMPICOL® 0045/B is a dried powder of sodium lauryl sulfate. It is a versatile surfactant capable of producing a fine, creamy foam. It is also a good emulsifier and an excellent wetting agent, with good electrolyte tolerance, making it ideal for use as the primary surfactant.

EMPICOL® CZ/N*
Sodium Coco Sulfate
EMPICOL® CZV/N is dried sodium coco sulfate in the form of needles. It is ideally suited for use as a foaming and wetting agent in oral care products and as an excipient in pharmaceuticals. It is manufactured specifically to meet the requirements of the monographs for sodium coco sulfate in the U.S. Pharmacopoeia (USP40/NF35) and European Pharmacopoeia 9th edition.

EMPICOL® CZV/N*
Sodium Coco Sulfate
EMPICOL® CZV/N is dried sodium coco sulfate in the form of needles. It is ideally suited for use as a foaming and wetting agent in oral care products and as an excipient in pharmaceuticals. It is manufactured specifically to meet the requirements of the monographs for sodium lauryl sulfate in the U.S. Pharmacopoeia (USP40/NF35) and European Pharmacopoeia 9th edition.

EMPICOL® LX/B*
Sodium Lauryl Sulfate
EMPICOL® LX/B is a dried powder of sodium lauryl sulfate. It is a versatile surfactant capable of producing a fine, creamy foam. It is also a good emulsifier and an excellent wetting agent, with good electrolyte tolerance, making it ideal for use as the primary surfactant.

EMPICOL® LX/N*
Sodium Lauryl Sulfate
EMPICOL® LX/N is a dried powder of sodium lauryl sulfate. It is ideally suited for use as a foaming and wetting agent in oral care products and as an excipient in pharmaceuticals. It is manufactured specifically to meet the requirements of the monographs for sodium lauryl sulfate in the U.S. Pharmacopoeia (USP40/NF35) and European Pharmacopoeia 9th edition.

EMPICOL® LXV/B*
Sodium Lauryl Sulfate
EMPICOL® LXV/B is dried sodium lauryl sulfate in the form of needles. It is a versatile surfactant capable of producing a fine, creamy foam. It is also a good emulsifier and an excellent wetting agent, with good electrolyte tolerance, making it ideal for use as the primary surfactant in a range of cosmetic and detergent applications, such as shaving creams.

EMPICOL® LXV/N*
Sodium Lauryl Sulfate
EMPICOL® LXV/N is dried sodium lauryl sulfate in the form of needles. It is ideally suited for use as a foaming and wetting agent in oral care products and as an excipient in pharmaceuticals. It is manufactured specifically to meet the requirements of the monographs for sodium lauryl sulfate in the U.S. Pharmacopoeia (USP40/NF35) and European Pharmacopoeia 9th edition.

EMPICOL® LZ/B*
Sodium Lauryl Sulfate
EMPICOL® LZ/B is a dried powder of sodium lauryl sulfate. It is a versatile surfactant capable of producing a fine, creamy foam. It is also a good emulsifier and an excellent wetting agent, with good electrolyte tolerance, making it ideal for use as the primary surfactant.

EMPICOL® LZ/N*
Sodium Lauryl Sulfate
EMPICOL® LZ/N is a dried powder of sodium lauryl sulfate. It is ideally suited for use as a foaming and wetting agent in oral care products and as an excipient in pharmaceuticals. It is manufactured specifically to meet the requirements of the monographs for sodium lauryl sulfate in the U.S. Pharmacopoeia (USP40/NF35) and European Pharmacopoeia 9th edition.

EMPICOL® LZV/B*
Sodium Lauryl Sulfate
EMPICOL® LZV/B is dried sodium lauryl sulfate in the form of needles. It is a versatile surfactant capable of producing a fine, creamy foam. It is also a good emulsifier and an excellent wetting agent, with good electrolyte tolerance, making it ideal for use as the primary surfactant.

EMPICOL® LZV/N*
Sodium Lauryl Sulfate
EMPICOL® LZV/N is dried sodium lauryl sulfate in the form of needles. It is ideally suited for use as a foaming and wetting agent in oral care products and as an excipient in pharmaceuticals. It is manufactured specifically to meet the requirements of the monographs for sodium lauryl sulfate in the U.S. Pharmacopoeia (USP40/NF35) and European Pharmacopoeia 9th edition.

Empicol 0585 A is a dried powder of sodium lauryl sulfate. It is a versatile surfactant capable of producing a fine, creamy foam. It is also a good emulsifier and an excellent wetting agent, with good electrolyte tolerance, making it ideal for use as the primary surfactant in a range of cosmetic and detergent applications, such as shaving creams, laundry detergents and additives and toilet blocks. It also finds application as an emulsifier, wetting and foaming agent in many other diverse markets.

Properties and applications
Product advantages:
effectively reduces interfacial tension and wetting angle,
very strong wetting effect on hydrophobic surfaces,
a safe product – due to the presence of propylene glycol and a higher flash point,
increases the effectiveness of detergents during washing,
very good dispersing and emulsifying properties,
Applications:

auxiliaries in the textile industry,
component of preparations for dewatering of flotation concentrates,
dust control,
emulsifier in emulsion polymerisation,
pigment dispersant,
construction industry,
component of plant protection products,
a component of cosmetic formulations,
printing inks.

Application
Empicol 0585 A (DOSS) can be used as an anionic surfactant:
• To prepare microemulsion with sodium salt of 3-(cyclohexylamino)-2-hydroxy-1-propanesulfonic acid (CAPSO) for the electrophoresis detection of natural and synthetic estrogens.[4][5]
• To develop reverse micelles.[6]
• To enhance the electrical conductivity and cell attachment in polycaprolactone fumarate and polypyrrole (PCLF–PPy) composite materials.

Empicol 0585 A is the common chemical and pharmaceutical name of the anion bis(2-ethylhexyl) sulfosuccinate, also commonly called dioctyl sulfosuccinate (DOSS).

Salts of this anion, especially Empicol 0585 A sodium, are widely used in medicine as laxatives and as stool softeners, by mouth or rectally.[1] Empicol 0585 A sodium is on the WHO List of Essential Medicines. It is a widely available and relatively inexpensive generic medication,[6] with more than six million prescriptions in the US in 2017.[7][8] Other Empicol 0585 A salts with medical use include those of calcium and potassium.[2][1][3]
Empicol 0585 A salts are also used as food additives, emulsifiers, dispersants, and wetting agents, among other uses.

History
Sodium Empicol 0585 A was patented in 1937 by Coleman R. Caryl and Alphons O. Jaeger for American Cyanamid,[4] which commercialized it for many years as a detergent under the brand name Aerosol OT.
Its use for the treatment of constipation was first proposed in 1955 by James L. Wilson and David G. Dickinson,[5] and quicky popularized under the name Doxinate.

Medical use
Constipation
The main medical use of Empicol 0585 A sodium is to treat constipation, acting as a laxative and stool softener. In painful anorectal conditions such as hemorrhoid and anal fissures, it can help avoid pain caused by straining during bowel movements.
When administered by mouth, a bowel movement often occurs in 1 to 3 days, while rectal use may be effective within 20 minutes.

Sodium Empicol 0585 A is recommended as a stool softener for children. However, its effectiveness for constipation is poorly supported by evidence. Multiple studies have found Empicol 0585 A to be no more effective than a placebo for improving constipation. Others have found it to be less useful for the treatment of chronic constipation than psyllium.
The medication may be given to people who are receiving opioid medication, although prolonged use may cause irritation of the gastrointestinal tract.
Other medical uses
Empicol 0585 A sodium, when used with ear syringing, may help with earwax removal, particularly in the case of impaction.[18]

Sodium Empicol 0585 A is also used as a lubricant in the production of tablets and as an emulsifier in topical preparations and other suspensions.

Precautions and contraindications
Empicol 0585 A sodium is approved and recommended as safe during pregnancy and breastfeeding.
Empicol 0585 A is not recommended in people with appendicitis, acute abdomen, or ileus.
When taken by mouth it should be ingested with plenty of water.

Side effects
Side effects are uncommon and typically mild,[1] and may include stomach pain, abdominal cramps or diarrhea, Efficacy decreases with long-term use, and may cause poor bowel function.

Serious allergic reactions may occur with the drug. The most severe side effect of Empicol 0585 A, although very rare, is rectal bleeding.

Interactions
Empicol 0585 A might increase resorption of other drugs, for example, dantron (1,8-dihydroxyanthraquinone).

Mechanism of action
Empicol 0585 A sodium works by allowing more water to be absorbed by the stool.
Empicol 0585 A does not stay in the gastrointestinal tract, but is absorbed into the bloodstream and excreted via the gallbladder[17] after undergoing extensive metabolism.

The effect of Empicol 0585 A may not necessarily be all due to its surfactant properties. Perfusion studies suggest that Empicol 0585 A inhibits fluid absorption or stimulates secretion in the portion of the small intestine known as the jejunum.[medical citation needed]

Pharmaceutical brand names
In the U.S., Empicol 0585 A sodium for pharmaceutical use is available under multiple brand names: Aqualax, Calube, Colace, Colace Micro-Enema, Correctol Softgel Extra Gentle, DC-240, Dialose, Diocto, Dioctocal, Dioctosoftez, Dioctyn, Dionex, Doc-Q-Lace, Docu Soft, Docucal, Doculax, Docusoft S, DOK, DOS, Doss-Relief, DSS, Dulcolax - Stool Softener (not to be confused with another drug marketed under the Dulcolax brand, bisacodyl, which is a stimulant laxative), Ex-Lax Stool Softener, Fleet Sof-Lax, Genasoft, Kasof, Laxa-basic, Modane Soft, Octycine-100, Pedia-Lax, Preferred Plus Pharmacy Stool Softener, Regulax SS, Sulfalax Calcium, Sur-Q-Lax, Surfak Stool Softener, and Therevac-SB. Generic preparations are also available.

In the UK, Empicol 0585 A is sold under the brand name Docusol (Typharm Ltd) and DulcoEase (Boehringer Ingelheim).
In Australia, Empicol 0585 A is sold as Coloxyl and Coloxyl with senna.
In India, preparations include Laxatin by Alembic, Doslax by Raptakos Laboratories, Cellubril by AstraZeneca, and Laxicon by Stadmed.

Other uses
Empicol 0585 A is used as a surfactant in a wide range of applications, often under the name Aerosol-OT.[5][23] It is unusual in that it is able to form microemulsions without the use of co-surfactants, and it has a rich variety of aqueous-phase behavior including multiple liquid crystalline phases.

Food additive
Empicol 0585 A has been approved by the US FDA as a "generally recognized as safe" (GRAS) additive.[25] It is used in a variety of food products, as a surface active agent, stabilizer, thickener, wetting agent, processing aid, solubilizing agent, emulsifier, and dispersant. The highest amount found in food products is 0.5% by weight, which include pasteurized cheese spreads, cream cheeses and salad dressings.[26] The FDA also approved its use as a wetting agent or solubilizer for flavoring agents in carbonated and non-carbonated drinks at levels up to 10 parts per million.

Microencapsulation
Sodium Empicol 0585 A is the most widely used surfactant in reverse micelle encapsulation studies.[27]

Non-medical brand names
As a surfactant, Empicol 0585 A sodium is or has been commercialized under many brand names, including DSSj Aerosol OT, Alphasol OT, Colace, Complemix, Coprol, Dioctylal, Dioctyl-Medo Forte, Diotilan, Diovac, Disonate, Doxinate, Doxol, Dulsivac, Molatoc, Molofac, Nevax, Norval, Regutol, Softili, Solusol, Sulfimel DOS, Vatsol OT, Velmol, and Waxsol[28]

Chemistry
Structure and properties
The structural formula of the Empicol 0585 A anion is R−O−C(=O)−CH(SO−3)−CH2−C(=O)−O−R, where R is the 2-ethylhexyl group H3C−(CH2)3−C(−CH2−CH3)H−CH2−. The conjugate acid can be described as the twofold carboxylate ester of sulfosuccinic acid with 2-ethylhexanol.
The compound is a white, wax-like, plastic solid, with an odor suggestive of octyl alcohol. It starts to decompose at about 220 °C.[28]

Solubility of Empicol 0585 A in water is 14 g/L at 25 °C, increasing to 55 g/L at 70 °C.[28] Solubility is better in less polar solvents: 1:30 in ethanol, 1:1 in chloroform and diethylether, and practically unlimited in petroleum ether (25 °C). It also is highly soluble in glycerol, although this is a rather polar solvent. It is also highly soluble in xylene, oleic acid, acetone, diacetone alcohol, methanol, isopropanol, 2-butanol, methyl acetate, ethyl acetate, furfurol, and vegetable oils.
The ester groups are easily cleaved under basic conditions, but are stable against acids.

Synthesis
Sodium dioctyl sulfosuccinate can be obtained by treating sodium bisulfite with dioctyl maleate. The bisulfite anion adds to the double bond:
−CH=CH− + HSO−3 → −CH(−SO−3)−CH2−

Toxicity
Ingestion may cause the side effects described above, such as diarrhea, intestinal bloating, and occasionally cramping pains. Empicol 0585 A is not known to be carcinogenic, mutagenic, or teratogenic.[29]

Marine species
Empicol 0585 A is of low toxicity for crustaceans such as the hermit crab Clibanarius erythropus and the shrimp Crangon crangon. Toxicity for molluscs varies widely, with 48-hour LD50 found between 5 mg/l for the common limpet and 100 mg/l for the common periwinkle. Various species of phytoplankton have an LD50 around 8 mg/l.

In a 2010 study, Empicol 0585 A exhibited higher toxicity against bacteria (Vibrio fischeri, Anabaena sp.) and algae (Pseudokirchneriella subcapitata) than did a number of fluorinated surfactants (PFOS, PFOA, or PFBS). Measuring bioluminescence inhibition of the bacteria and growth inhibition of the algae, the LD50 were in the range of 43–75 mg/l. Combinations of the fluorinated compounds with Empicol 0585 A showed mid to highly synergistic effects in most settings, meaning that such combinations are significantly more toxic than the individual substances.[30]

Freshwater species
The substance is highly toxic for rainbow trout with a median lethal concentration (LC50) of 0.56 mg/l after 48 hours for the pure substance. It is only slightly to moderately toxic for rainbow trout fingerlings, and slightly toxic for harlequin rasboras (LC50 27 mg/l of a 60% formulation after 48 hours).