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CAS NUMBER: 1071-93-8
MOLECULAR FORMULA: C6H14N4O2
MOLECULAR WEIGHT: 174.20
DESCRIPTION:
Hexanedihydrazide (Adipic dihydrazide) is a chemical used for cross-linking water-based emulsions.
Hexanedihydrazide (Adipic dihydrazide) can also be used as a hardener for certain epoxy resins.
Hexanedihydrazide (Adipic dihydrazide) is a symmetrical molecule with a C4 backbone and the reactive group is C=ONHNH2. Dihydrazides are made by the reaction of an organic acid with hydrazine.
Hexanedihydrazides (Adipic dihydrazide) with different backbones are also common, including isophthalic dihydrazide (IDH) and sebacic dihydrazide (SDH).
Hexanedihydrazide (Adipic dihydrazide) is pure white crystals.
Hexanedihydrazide (Adipic dihydrazide) is easily soluble in water and poisoned.
Hexanedihydrazide (Adipic dihydrazide) is used as epoxy powder coating curing agent and coating additive, metal deactivator and other polymer additives and water treatment agent.
Hexanedihydrazide (Adipic dihydrazide) is a homobifunctional cross-linking reagent that is specific for aldehydes.
This results in relatively stable hydrazone linkages.
Hexanedihydrazide (Adipic dihydrazide) is generally used in the linking of glycoproteins, like antibodies, in a site-specific fashion following periodate oxidation.
Oxidation and coupling may be performed at pH 5.0 due to the low pKa of the hydrazide which avoids competition by primary amines.
Hexanedihydrazide (Adipic dihydrazide) is an effective crosslinking agent, curative and hardener.
Hexanedihydrazide (Adipic dihydrazide) is the most common dihydrazide crosslinking agent within a series of dihydrazides such as sebacic dihydrazide (SDH) and isophthalic dihydrazide (IDH).
Hexanedihydrazide (Adipic dihydrazide)’s has a melting point of 180 °C and a molecular weight of 174; both are lower than the alternative dihydrazides SDH and IDH.
Hexanedihydrazide (Adipic dihydrazide) is used as a difunctional crosslinking agent in paints and coatings for certain water-based acrylic emulsions.
Hexanedihydrazide (Adipic dihydrazide) is used as a hardener for epoxy resins and a chain extender for polyurethanes.
A small use is as a formaldehyde scavenger preventing the liberation of formaldehyde.
The applications of Hexanedihydrazide (Adipic dihydrazide) are facilitated by the nucleophilicity of the amine function (good reaction characteristics), the good overall properties and weatherability of cured systems.
The moderate solubility of Hexanedihydrazide (Adipic dihydrazide) in water and common organic solvents facilitates the use of ADH in aqueous and solvent based systems.
PROPERTIES:
-form: powder
-autoignition temp.: 360 °C
-mp: 178-182 °C
-transition temp: flash point >150 °C
-storage temp.: 15-25°C
PHYSICAL AND CHEMICAL PROPERTIES:
-Flash point: 150 °C
-Ignition temperature: 360 °C
-Melting Point: 180 - 182 °C
SPECIFICATION:
-Melting range (lower value): ≥ 178 °C
-Melting range (upper value): ≤ 182 °C
STORAGE:
Store long-term in a cool, dry place.
PRODUCT INFORMATION:
-CAS number: 1071-93-8
-EC number: 213-999-5
-Hill Formula: C₆H₁₄N₄O₂
-Molar Mass: 174.2 g/mol
-HS Code: 2928 00 90
DEFINITION:
Hexanedihydrazide (Adipic dihydrazide) is used as a formaldehyde scavenger and reacts with formaldehyde, thereby preventing the volatilizing of formaldehyde in the air.
Hexanedihydrazide (Adipic dihydrazide) is also employed as a paint additive and coating additive.
Hexanedihydrazide (Adipic dihydrazide) is also used as an intermediate.
Hexanedihydrazide (Adipic dihydrazide) is used for cross-linking water-based emulsions and as a hardener for certain epoxy resins, which finds application in powder coating.
Hexanedihydrazide (Adipic dihydrazide) is a chemical used for cross-linking water-based emulsions.
Hexanedihydrazide (Adipic dihydrazide) can also be used as a hardener for certain epoxy resins.
Hexanedihydrazide (Adipic dihydrazide) is used in the linking of glycoproteins, such as antibodies, in a site specific fashion following periodate oxidation.
Hexanedihydrazide (Adipic dihydrazide) is a chemical used for cross-linking water-based emulsions.
Hexanedihydrazide (Adipic dihydrazide) can also be used as a hardener for certain epoxy resins.
Hexanedihydrazide (Adipic dihydrazide) is a symmetrical molecule with a C4 backbone and the reactive group is C=ONHNH2.
Hexanedihydrazides (Adipic dihydrazide) are made by the reaction of an organic acid with hydrazine.
Hexanedihydrazides (Adipic dihydrazide) with different backbones are also common, including isophthalic dihydrazide (IDH) and sebacic dihydrazide (SDH).
A notable fact with regard to Hexanedihydrazide (Adipic dihydrazide) in epoxy formulations is that each of the primary amine end groups has a functionality of two, so the ADH molecule has an equivalency of four per epoxy moiety.
Accordingly, the active hydrogen equivalent weight of Hexanedihydrazide (Adipic dihydrazide) is 43.5.
When formulated with epoxy resins, the Hexanedihydrazide (Adipic dihydrazide) index can range between 0.85-1.15 of stoichiometric proportions, without a significant effect on mechanical properties.
The cure temperature for epoxy resins (glycidyl types) formulated with Hexanedihydrazide (Adipic dihydrazide) is influenced by the melt-out temperature of the ADH, which allows an extended pot life at low temperatures.
Storage stability can be up to six-months at room temperature, with cure times of about one-hour at 130 °C.
Cure rates can be accelerated using tin or titanate catalysts, or imidazoles.
One-component Hexanedihydrazide (Adipic dihydrazide) epoxy systems can be partially cured or “B-staged”, and later fully cured.
Hexanedihydrazide (Adipic dihydrazide) is an effective room temperature curative for solution polyurethanes.
Hexanedihydrazide (Adipic dihydrazide) provides polyurea coatings with higher hardness, toughness and adhesion properties, excellent mechanical properties, abrasion and chemical resistance.
Hexanedihydrazide (Adipic dihydrazide) cured polyurethane coatings exhibit good color stability and weathering properties, which is not observed with standard amine curatives.
Hexanedihydrazide (Adipic dihydrazide), white crystalline solid, with symmetrical molecular structure, is double-functional group compound.
Hexanedihydrazide (Adipic dihydrazide) is a kind of good crosslinking agent, can be crosslinked with carbonyl, more typically has and is applied to medicine and pharmacology with cross-linking hyaluronic acid.
Hexanedihydrazide (Adipic dihydrazide) is a homobifunctional cross-linking reagent specific for aldehydes resulting in relatively stable hydrazone linkages.
Hexanedihydrazide (Adipic dihydrazide) is typically, used in the linking of glycoproteins, such as antibodies, in a site specific fashion following periodate oxidation.
Oxidation and coupling may conveniently be performed at pH 5.0 due to the low pKa of the hydrazide which avoids competition by primary amines.
Hexanedihydrazide (Adipic dihydrazide) is used as chain extender in the preparation of waterborne polyurethane binders and secondly as crosslinker in waterbased coatings.
Hexanedihydrazide (Adipic dihydrazide) is widely used as cross-linker in waterborne acrylic emulsions.
Hexanedihydrazide (Adipic dihydrazide) is a good cross-linking agent which has been widely used.
Hexanedihydrazide (Adipic dihydrazide) is often used to crosslink with hyaluronic acid to prepare hyaluronic acid derivatives or as a drug carrier.
Hexanedihydrazide (Adipic dihydrazide) is a ketonehydrazine crosslinking monomer, so its cross-linking with DAAM crosslinking is a typical room temperature self-crosslinking, which is widely used in water-based resin and can significantly improve the performance of water-based resin products.
Hexanedihydrazide (Adipic dihydrazide) is synthesized by the two-stage method, i.e. first methanol is used as the raw material to have esterification reaction with adipic acid to form dimethyl adipate, and then dimethyl adipate and hydrazine hydrate have the hydrazide reaction to synthesize ADH.
PRODUCT INFORMATION:
-Product Number: A0170
-Purity / Analysis Method: >99.0%(HPLC)
-Molecular Formula / Molecular Weight: C6H14N4O2 = 174.20
-Physical State (20 deg.C): Solid
-Store Under Inert Gas: Store under inert gas
-Condition to Avoid: Air Sensitive
-CAS RN: 1071-93-8
-Reaxys Registry Number: 973863
-PubChem Substance ID: 87561852
-SDBS (AIST Spectral DB): 1470
-MDL Number: MFCD00007614
APPLICATION:
Hexanedihydrazide (Adipic dihydrazide) is soluble in water, alcohol and acetone.
Hexanedihydrazide (Adipic dihydrazide) is commonly used in the linking of glycoproteins, such as antibodies, in a site specific fashion following periodate oxidation.
Hexanedihydrazide (Adipic dihydrazide) is the most suitable hydrazide cross-linking agent, and ADH has been widely used in water-based paint emulsions in combination with diacetone acrylamide. ADH is weakly alkaline, and there is a possibility of agglomeration when solid ADH is added directly to the emulsion, so usually ADH should be dissolved in hot water before use.
Hexanedihydrazide (Adipic dihydrazide) is used as a formaldehyde scavenger and reacts with formaldehyde, thereby preventing the volatilizing of formaldehyde in the air.
Hexanedihydrazide (Adipic dihydrazide) is also employed as a paint additive and coating additive.
Hexanedihydrazide (Adipic dihydrazide) is also used as an intermediate.
Hexanedihydrazide (Adipic dihydrazide) is used for cross-linking water-based emulsions and as a hardener for certain epoxy resins, which finds application in powder coating.
Hexanedihydrazide (Adipic dihydrazide) is a homobifunctional cross-linking reagent specific for aldehydes resulting in relatively stable hydrazone linkages.
Hexanedihydrazide (Adipic dihydrazide) is typically, used in the linking of glycoproteins, such as antibodies, in a site specific fashion following periodate oxidation.
Oxidation and coupling may conveniently be performed at pH 5.0 due to the low pKa of the hydrazide which avoids competition by primary amines.
Hexanedihydrazide (Adipic dihydrazide) is used to functionalize magnetic nanoparticles for gylcopeptitde enrichment and identification.
Hexanedihydrazide (Adipic dihydrazide) can also be used as a chain extension for liquid rubber.
Hexanedihydrazide (Adipic dihydrazide) is a chemcial intermediate and specialty chemical often used in adhesive and coating-manufacturing applications.
Hexanedihydrazide (Adipic dihydrazide) offers amino- and keto-functionality at either end of the molecule which makes it an excellent cross-linking agent for water-based emulsions.
SPECIFICATION:
-Melting Point: 180°C to 182°C
-Odor: Odorless
-Solubility Information: Soluble in water,alcohol and acetone.
-Formula Weight: 174.2
-Percent Purity: 97%
TECHNICAL INFORMATION:
-Appearance: Powder
-Physical State: Solid
-Solubility: Soluble in Water: 100 mg/mL
-Storage: Store at -20° C
-Melting Point: 180-182° C (lit.)
CLASS:
-Specialty Chemicals
-Chemical Intermediates
-Adhesives
-Coatings and Sealants Chemicals
FUNCTION:
-Intermediates
-Cross-linking Agent
USAGE AREAS:
-Industrial
-Resin & Coating
-Specialty Chemicals
-Plastics
SYNONYM:
Adipic dihydrazide
1071-93-8
Adipohydrazide
Adipic acid dihydrazide
Hexanedihydrazide
Hexanedioic acid, dihydrazide
Adipic acid, dihydrazide
Adipyl hydrazide
Adipodihydrazide
VK98I9YW5M
Hexanediohydrazide
WLN: ZMV4VMZ
MFCD00007614
Adip dihydr
Adipoyl hydrazide
Adipoyldihydrazine
adipic dihydrazone
adipoyl dihydrazide
Hexanedioic acid, 1,6-dihydrazide
Hexanedihydrazide #
NSC 3378
EINECS 213-999-5
NSC 29542
Adipic aciddihydrazide
Adipic acid dihyrazide
Hexanedioic dihydrazide
adipic acid dihydrizide
AI3-22640
UNII-VK98I9YW5M
EC 213-999-5
Hexanedioic acid dihydrazide
DSSTox_CID_24361
DSSTox_RID_8016
DSSTox_GSID_44361
SCHEMBL49856
Adipic Acid Dihydrazide (ADH)
CHEMBL3185968
DTXSID0044361
SCHEMBL11037942
AMY3771
NSC3378
1,4-Butanedicarboxylic dihydrazide
ALBB-011767
NSC-3378
NSC29542
STR02658
ZINC1666741
Tox21_301067
BBL022965
NSC-29542
STK709135
AKOS000267183
NCGC00248276-01
NCGC00257525-01
CAS-1071-93-8
DB-022418
A0170
Adipic acid dihydrazide, >=98% (titration)
CS-0010116
FT-0621914
D72486
Adipic acid dihydrazide, purum, >=97.0% (NT)
A801603
J-660023
Q-200600
Q4682936
Z56812730
F1943-0024
