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ISOPROPYL MYRISTATE (IPM)

Isopropyl Myristate (IPM) is used in the following products: washing & cleaning products, metal surface treatment products and lubricants and greases.
Isopropyl Myristate (IPM) is used in the following areas: formulation of mixtures and/or re-packaging.
Isopropyl Myristate (IPM) is used for the manufacture of: chemicals.


CAS Number: 110-27-0 
EC Number: 203-751-4
MDL number: MFCD00008982
Linear Formula: CH3(CH2)12COOCH(CH3)2
Molecular Formula: C17H34O2

SYNONYMS:
ISOPROPYL MYRISTATE, 110-27-0, Isopropyl tetradecanoate, Estergel, Tetradecanoic acid, 1-methylethyl ester, Bisomel, Isomyst, Promyr, Deltyl Extra, Kesscomir, Tegester, propan-2-yl tetradecanoate, Sinnoester MIP, Crodamol IPM, Plymoutm IPM, Starfol IPM, Unimate IPM, Kessco IPM, Emcol-IM, Wickenol 101, Myristic acid isopropyl ester, Stepan D-50, Emerest 2314, 1-Methylethyl tetradecanoate, Deltylextra, JA-FA IPM, Crodamol I.P.M., Kessco isopropyl myristate, Tetradecanoic acid, isopropyl, FEMA No. 3556, Myristic acid, isopropyl ester, Tetradecanoic acid, isopropyl ester, Caswell No. 511E, Isopropyl myristate [USAN], 1-Tridecanecarboxylic acid, isopropyl ester, HSDB 626, NSC 406280, UNII-0RE8K4LNJS, 0RE8K4LNJS, EINECS 203-751-4, MFCD00008982, Estergel (TN), EPA Pesticide Chemical Code 000207, NSC-406280, BRN 1781127, methylethyl tetradecanoate, iso-Propyl N-tetradecanoate, DTXSID0026838, CHEBI:90027, EC 203-751-4, Tetradecanoic acid methyethyl ester, 1405-98-7, NCGC00164071-01, WE(2:0(1Me)/14:0), isopropylmyristate, MYRISTIC ACID, ISOPROPYL ALCOHOL ESTER, Isopropyl myristate, 98%, TETRADECONOIC ACID, 1-METHYLETHYL ESTER, DTXCID306838, ISOPROPYL MYRISTATE (II), ISOPROPYL MYRISTATE [II], ISOPROPYL MYRISTATE (MART.), ISOPROPYL MYRISTATE [MART.], ISOPROPYL MYRISTATE (USP-RS), ISOPROPYL MYRISTATE [USP-RS], CAS-110-27-0, ISOPROPYL MYRISTATE (EP MONOGRAPH), ISOPROPYL MYRISTATE [EP MONOGRAPH], IPM-EX, Isopropyl myristate; 1-Methylethyl tetradecanoate, IPM-R, tetradecanoic acid 1-methylethyl ester, Deltyextra, Myristic acid-isopropyl ester, Tegosoft M, Isopropyl myristate [USAN:NF], Liponate IPM, Crodamol 1PM, IPM 100, isopropyl-myristate, Lexol IPM, Isopropyltetradecanoate, Radia 7190, Isopropyl myristate (NF), Isopropyl tetradecanoic acid, SCHEMBL2442, Isopropyl myristate, >=98%, Isopropyl myristate (Standard), CHEMBL207602, ISOPROPYL MYRISTATE [MI], WLN: 13VOY1&1, FEMA 3556, tetradecanoic acid isopropyl ester, ISOPROPYL MYRISTATE [FHFI], ISOPROPYL MYRISTATE [HSDB], ISOPROPYL MYRISTATE [VANDF], Isopropyl myristate, >=90% (GC), Tox21_112080, Tox21_202065, Tox21_303171, ISOPROPYL MYRISTATE [WHO-DD], LMFA07010677, NSC406280, s2428, AKOS015902296, Tox21_112080_1, DB13966, HY-124190R, USEPA/OPP Pesticide Code: 000207, NCGC00164071-02, NCGC00164071-03, NCGC00256937-01, NCGC00259614-01, LS-14615, DB-040910, HY-124190, CS-0085813, M0481, NS00006471, Isopropyl Myristate Solution. 500mL, Sterile, D02296, F71211, SBI-0654218.0001, EN300-25299830, Q416222, SR-01000944751, Isopropyl myristate, Vetec(TM) reagent grade, 98%, Q-201418, SR-01000944751-1, BRD-K13409143-001-01-9, Isopropyl myristate, United States Pharmacopeia (USP) Reference Standard, TETRADECANOIC ACID,ISOPROPYL ESTER (MYRISTATE,ISOPROPYL ESTER), Isopropyl myristate, Pharmaceutical Secondary Standard; Certified Reference Material, InChI=1/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H, IPM, 1-Methylethyl tetradecanoate, MYRISTIC ACID ISOPROPYL ESTER, IPM 100, BISOMEL, Propyl myristate, sopropyl myristate, ISOPROPYL TETRADECANOATE, ISO-PROPYL N-TETRADECANOATE, MYRISTIC ACID ISOPROPYL ESTER MINIMU, Tetradecanoic acid, 1-methylethyl ester, propan-2-yl tetradecanoate, Estergel, Tetradecanoic acid 1-methylethyl ester, myristic acid and isopropanol ester, IPM, rubbing alcohol, tetradecanoic acid 2-propyl ester, 2-propyl tetradecanoate, DUB IPM, Tetradecanoic acid, 1-methylethyl ester, Myristic acid, isopropyl ester, Bisomel, Crodamol I.P.M., Crodamol IPM, Deltyl Extra, Emcol-IM, Isomyst, Isopropyl tetradecanoate, Kessco IPM, Kesscomir, Promyr, Sinnoester MIP, Stepan D-50, Wickenol 101, Emerest 2314, Estergel, Ja-fa IPM, Kessco isopropyl myristate, Plymoutm IPM, Starfol IPM, Tegester, Tetradecanoic acid, isopropyl, Tetradecanoic acid, isopropyl ester, Unimate IPM, 1-Tridecanecarboxylic acid, isopropyl ester, D 50, 1-Methylethyl tetradecanoate, IPM, Lexol IPM, Liponate IPM, Radia 7190, Tegosoft M, iso-Propyl N-tetradecanoate, Methylethyl tetradecanoate, Tetradecanoic acid methyethyl ester, NSC 406280, component of Sardo Bath Oil, 1405-98-7, ISOPROPYL MYRISTATE, 110-27-0, Isopropyl tetradecanoate, Estergel, Isomyst, Bisomel, Promyr, Tetradecanoic acid, 1-methylethyl ester, Deltyl Extra, Kesscomir, Tegester, Sinnoester MIP, Crodamol IPM, Plymoutm IPM, Starfol IPM, Unimate IPM, Kessco IPM, Stepan D-50, Emcol-IM, Wickenol 101, Emerest 2314, propan-2-yl tetradecanoate, 1-Methylethyl tetradecanoate, Deltylextra, Myristic acid isopropyl ester, JA-FA IPM, Crodamol I.P.M., Kessco isopropyl myristate, FEMA No. 3556, Tetradecanoic acid, isopropyl, Myristic acid, isopropyl ester, Tetradecanoic acid, isopropyl ester, Caswell No. 511E, HSDB 626, NSC 406280, Isopropyl myristate [USAN], 1-Tridecanecarboxylic acid, isopropyl ester, UNII-0RE8K4LNJS, 0RE8K4LNJS, EINECS 203-751-4, Estergel (TN), EPA Pesticide Chemical Code 000207, NSC-406280, BRN 1781127, methylethyl tetradecanoate, tetradecanoic acid 1-methylethyl ester, iso-Propyl N-tetradecanoate, Isopropyl myristate [USAN:NF], DTXSID0026838, CHEBI:90027, EC 203-751-4, Tetradecanoic acid methyethyl ester, 1405-98-7, NCGC00164071-01, WE(2:0(1Me)/14:0), MYRISTIC ACID, ISOPROPYL ALCOHOL ESTER, Isopropyl myristate, 98%, TETRADECONOIC ACID, 1-METHYLETHYL ESTER, DTXCID306838, ISOPROPYL MYRISTATE (II), ISOPROPYL MYRISTATE [II], ISOPROPYL MYRISTATE (MART.), ISOPROPYL MYRISTATE [MART.], ISOPROPYL MYRISTATE (USP-RS), ISOPROPYL MYRISTATE [USP-RS], CAS-110-27-0, ISOPROPYL MYRISTATE (EP MONOGRAPH), ISOPROPYL MYRISTATE [EP MONOGRAPH], MFCD00008982, Deltyextra, Tegosoft M, Liponate IPM, Crodamol 1PM, isopropyl-myristate, Lexol IPM, Crodamol I.P.M, isopropyl myristate, Isopropyltetradecanoate, myristic acid isopropyl, Radia 7190, Isopropyl myristate (NF), Isopropyl tetradecanoic acid, MYRISTATE, ISOPROPYL, SCHEMBL2442, Myristic acid-isopropyl ester, Isopropyl myristate, >=98%, CHEMBL207602, ISOPROPYL MYRISTATE [MI], WLN: 13VOY1&1, FEMA 3556, tetradecanoic acid isopropyl ester, ISOPROPYL MYRISTATE [FHFI], ISOPROPYL MYRISTATE [HSDB], ISOPROPYL MYRISTATE [INCI], ISOPROPYL MYRISTATE [VANDF], Isopropyl myristate, >=90% (GC), Tox21_112080, Tox21_202065, Tox21_303171, ISOPROPYL MYRISTATE [WHO-DD], LMFA07010677, NSC406280, s2428, AKOS015902296, Tox21_112080_1, DB13966, LS-2869, USEPA/OPP Pesticide Code: 000207, NCGC00164071-02, NCGC00164071-03, NCGC00256937-01, NCGC00259614-01, HY-124190, CS-0085813, FT-0629053, M0481, D02296, F71211, Isopropyl myristate, 1-Methylethyl tetradecanoate, EN300-25299830, Q416222, SR-01000944751, Isopropyl myristate, Vetec(TM) reagent grade, 98%, Q-201418, SR-01000944751-1, Isopropyl myristate, Myristic acid, isopropyl ester, (Tetradecanoic acid, isopropyl, Isopropyl myristate), InChI=1/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H, Propan-2-yl tetradecanoate, Tetradecanoic acid, 1-methylethyl ester, Myristic acid isopropyl ester, IPM, IPM 100, IPM-EX, IPM-R, Isopropyl tetradecanoate, Myristic acid isopropyl ester, Tetradecanoic acid, 1-methylethyl ester, Myristic acid, isopropyl ester, Bisomel, Crodamol I.P.M., Crodamol IPM, Deltyl Extra, Emcol-IM, Isomyst, Isopropyl tetradecanoate, Kessco IPM, Kesscomir, Promyr, Sinnoester MIP, Stepan D-50, Wickenol 101, Emerest 2314, Estergel, Ja-fa IPM, Kessco isopropyl myristate, Plymoutm IPM, Starfol IPM, Tegester, Tetradecanoic acid, isopropyl, Tetradecanoic acid, isopropyl ester, Unimate IPM, 1-Tridecanecarboxylic acid, isopropyl ester, D 50, 1-Methylethyl tetradecanoate, IPM, Lexol IPM, Liponate IPM, Radia 7190, Tegosoft M, iso-Propyl N-tetradecanoate, Methylethyl tetradecanoate, Tetradecanoic acid methyethyl ester, NSC 406280, 1405-98-7, ISOPROPYL MYRISTATE, 110-27-0, Isopropyl tetradecanoate, Estergel, Isomyst, Tetradecanoic acid, 1-methylethyl ester, Bisomel, Promyr, Deltyl Extra, Kesscomir, Tegester, Sinnoester MIP, Crodamol IPM, Plymoutm IPM, Starfol IPM, Unimate IPM, Kessco IPM, Stepan D-50, Emcol-IM, propan-2-yl tetradecanoate, Wickenol 101, Emerest 2314, 1-Methylethyl tetradecanoate, Deltylextra, Myristic acid isopropyl ester, JA-FA IPM, Crodamol I.P.M., Kessco isopropyl myristate, FEMA No. 3556, Tetradecanoic acid, isopropyl, Myristic acid, isopropyl ester, Tetradecanoic acid, isopropyl ester, Caswell No. 511E, HSDB 626, NSC 406280, Isopropyl myristate [USAN], 1-Tridecanecarboxylic acid, isopropyl ester, UNII-0RE8K4LNJS, 0RE8K4LNJS, EINECS 203-751-4, Estergel (TN), EPA Pesticide Chemical Code 000207, NSC-406280, BRN 1781127, methylethyl tetradecanoate, MFCD00008982, iso-Propyl N-tetradecanoate, DTXSID0026838, CHEBI:90027, EC 203-751-4, Tetradecanoic acid methyethyl ester, 1405-98-7, NCGC00164071-01, WE(2:0(1Me)/14:0), MYRISTIC ACID, ISOPROPYL ALCOHOL ESTER, Isopropyl myristate, 98%, TETRADECONOIC ACID, 1-METHYLETHYL ESTER, DTXCID306838, ISOPROPYL MYRISTATE (II), ISOPROPYL MYRISTATE [II], ISOPROPYL MYRISTATE (MART.), ISOPROPYL MYRISTATE [MART.], ISOPROPYL MYRISTATE (USP-RS), ISOPROPYL MYRISTATE [USP-RS], CAS-110-27-0, ISOPROPYL MYRISTATE (EP MONOGRAPH), ISOPROPYL MYRISTATE [EP MONOGRAPH], IPM-EX, IPM-R, tetradecanoic acid 1-methylethyl ester, Deltyextra, Myristic acid-isopropyl ester, Tegosoft M, Isopropyl myristate [USAN:NF], Liponate IPM, Crodamol 1PM, IPM 100, isopropyl-myristate, Lexol IPM, Isopropyltetradecanoate, Radia 7190, Isopropyl myristate (NF), Isopropyl tetradecanoic acid, SCHEMBL2442, Isopropyl myristate, >=98%, CHEMBL207602, ISOPROPYL MYRISTATE [MI], WLN: 13VOY1&1, FEMA 3556, tetradecanoic acid isopropyl ester, ISOPROPYL MYRISTATE [FHFI], ISOPROPYL MYRISTATE [HSDB], ISOPROPYL MYRISTATE [INCI], ISOPROPYL MYRISTATE [VANDF], Isopropyl myristate, >=90% (GC), Tox21_112080, Tox21_202065, Tox21_303171, ISOPROPYL MYRISTATE [WHO-DD], LMFA07010677, NSC406280, s2428, AKOS015902296, Tox21_112080_1, DB13966, USEPA/OPP Pesticide Code: 000207, NCGC00164071-02, NCGC00164071-03, NCGC00256937-01, NCGC00259614-01, LS-14615, HY-124190, CS-0085813, FT-0629053, M0481, NS00006471, D02296, F71211, Isopropyl myristate, 1-Methylethyl tetradecanoate, EN300-25299830, Q416222, SR-01000944751, Isopropyl myristate, Vetec(TM) reagent grade, 98%, Q-201418, SR-01000944751-1, Isopropyl myristate, United States Pharmacopeia (USP) Reference Standard, TETRADECANOIC ACID, ISOPROPYL ESTER (MYRISTATE,ISOPROPYL ESTER), Isopropyl myristate, Pharmaceutical Secondary Standard; Certified Reference Material, InChI=1/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H, Tetradecanoic acid, 1-methylethyl ester, Myristic acid, isopropyl ester, Bisomel, Crodamol I.P.M., Crodamol IPM, Deltyl Extra, Emcol-IM, Isomyst, Isopropyl tetradecanoate, Kessco IPM, Kesscomir, Promyr, Sinnoester MIP, Stepan D-50, Wickenol 101, Emerest 2314, Estergel, Ja-fa IPM, Kessco isopropyl myristate, Plymoutm IPM, Starfol IPM, Tegester, Tetradecanoic acid, isopropyl, Tetradecanoic acid, isopropyl ester, Unimate IPM, 1-Tridecanecarboxylic acid, isopropyl ester, D 50, 1-Methylethyl tetradecanoate, IPM, Lexol IPM, Liponate IPM, Radia 7190, Tegosoft M, iso-Propyl N-tetradecanoate, Methylethyl tetradecanoate, Tetradecanoic acid methyethyl ester, NSC 406280, component of Sardo Bath Oil, 1405-98-7, Tetradecanoic acid, 1-methylethyl ester, Myristic acid, isopropyl ester, Bisomel, Crodamol I.P.M., Crodamol IPM, Deltyl Extra, Emcol-IM, Isomyst, Isopropyl tetradecanoate, Kessco IPM, Kesscomir, Promyr, Sinnoester MIP, Stepan D-50, Wickenol 101, Emerest 2314, Estergel, Ja-fa IPM, Kessco isopropyl myristate, Plymoutm IPM, Starfol IPM, Tegester, Tetradecanoic acid, isopropyl, Tetradecanoic acid, isopropyl ester, Unimate IPM, 1-Tridecanecarboxylic acid, isopropyl ester, D 50, 1-Methylethyl tetradecanoate, IPM, Lexol IPM, Liponate IPM, Radia 7190, Tegosoft M, iso-Propyl N-tetradecanoate, Methylethyl tetradecanoate, Tetradecanoic acid methyethyl ester, NSC 406280, component of Sardo Bath Oil, 1405-98-7

Isopropyl Myristate (IPM), also commonly known as IPM is a clear, light yellow liquid which oily in appearance and virtually odourless. 
Isopropyl Myristate (IPM) is soluble in most solvents but considered insoluble in water. 
Isopropyl Myristate (IPM) is manufactured by the esterification of isopropyl alcohol with myristic acid (a fatty acid found in coconut oil and other natural sources).


Isopropyl Myristate (IPM) is composed of of isopropyl alcohol and myristic acid, a common, naturally occurring fatty acid.
Isopropyl myristate (IPM) is the ester of isopropyl alcohol and myristic acid. 
Isopropyl myristate (IPM) is a polar emollient and is used in cosmetic and topical medicinal preparations where good absorption into the skin is desired.


Isopropyl myristate (IPM) is the ester of isopropyl alcohol and myristic acid.
Hydrolysis of the ester from Isopropyl Myristate (IPM) can liberate the acid and the alcohol. 
Isopropyl Myristate (IPM) is theorized to be responsible for decreasing of the pH value of formulations


Isopropyl Myristate (IPM) is the ester of isopropyl alcohol and myristic acid. 
Isopropyl Myristate (IPM) mainly works as an emollient in cosmetics and personal care products. 
Isopropyl Myristate (IPM) has an oily base with low viscosity and adapts well to the skin.


Isopropyl Myristate (IPM) is a common ingredient in cosmetics and personal care products. 
Isopropyl Myristate (IPM) can be found in skin care products, lotions, creams, makeup, and sunscreens. 
The primary function of isopropyl myristate is to help products spread more easily onto the skin and make contact easier. 


Isopropyl Myristate (IPM) can also help products feel smoother and more lubricated.
Isopropyl Myristate (IPM) may be an ingredient that can increase skin moisture. 
People with sensitive skin should seek advice from a dermatologist or specialist before using products containing this ingredient.


Isopropyl Myristate (IPM) is also important to check if products containing this ingredient contain a sun protection factor (SPF), as some sunscreens and lotions may contain isopropyl myristate. 
If sun protection is an important factor, Isopropyl Myristate (IPM) is important to read product labels carefully and review the SPF content.


Isopropyl Myristate (IPM) is a moisturizer with polar characteristics used in cosmetics and topical medical preparations to ameliorate the skin absorption. 
Isopropyl Myristate (IPM) has been largely studied and impulsed as a skin penetration enhancer. 
At the moment the primary usage for which isopropyl myristate is formally indicated is as the active ingredient in a non-prescription pediculicide rinse.


Isopropyl Myristate (IPM) has been reported in Solanum tuberosum, Siraitia grosvenorii, and other organisms with data available.
Isopropyl Myristate (IPM) is a colorless, liquid oleochemical derived from esterized Myristic acid and Isopropyl alcohol. 
Isopropyl Myristate (IPM) is a common ingredient in cosmetic products, particularly moisturizing personal care products like lotions, creams, or serums. 


Isopropyl Myristate (IPM) is an extremely effective emollient and can act as a thickening or lubricating agent.
Isopropyl Myristate (IPM) is unique in that it enhances the penetration of other ingredients in a formulation, allowing for a variety of applications. 
Isopropyl Myristate (IPM) carries RSPO-MB Certification, one of four certification levels offered by the RSPO which monitors the trade of sustainably certified and non-sustainably certified palm oil. 


The Mass Balance certification allows the overall production of both RSPO and non-RSPO certified palm oil to maintain an even balance, hence Isopropyl Myristate (IPM)'s Mass Balance designation, with administrative traceability of the input and mixing of RSPO and non-RSPO certified palm oil, but at controlled quantities.


Isopropyl Myristate (IPM) is odorless when pure. 
Isopropyl Myristate (IPM) may be synthesized by conventional esterification of isopropanol with myristic acid.
Isopropyl Myristate (IPM) is an ester of isopropyl alcohol and myristic acid.


Also known as IPM, Isopropyl Myristate (IPM) is an all-natural ester derived from vegetable origin. 
Isopropyl Myristate (IPM) is a lightweight, fast-absorbing emollient that enhances the sensory appeal and functionality of personal care and cosmetic formulations. 


Isopropyl Myristate (IPM) is an emollient ester of low viscosity; the product of the reaction of isopropanol with myristic acid (vegetable source). 
A non-greasy emollient, Isopropyl Myristate (IPM) is readily adsorbed by the skin. 
Miscible with most oils, Isopropyl Myristate (IPM) imparts a dry, velvety emollience to products. 


Isopropyl Myristate (IPM) is resistant to oxidation and will not become rancid. 
Isopropyl Myristate (IPM) is also an effective diluent for fragrance oils.
Isopropyl Myristate (IPM) is an ester of isopropyl alcohol myristic acid. 


Isopropyl Myristate (IPM) is mainly used as a solubilizer, emulsifier and emollient in cosmetic and topical medicines. 
Isopropyl Myristate (IPM) also finds applications as a flavoring agent in the food industry.


Pharmaceutical secondary standards for application of Isopropyl Myristate (IPM) in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.


Isopropyl Myristate (IPM) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
Isopropyl Myristate (IPM) is a synthetic oil widely used in the cosmetics and pharmaceutical industries as a lubricant, emollient, and as a non-toxic alternative for controlling head lice. 


Isopropyl Myristate (IPM) is manufactured by condensing myristic acid with isopropyl alcohol and is colorless and mild in odor.
Isopropyl Myristate (IPM) is an ester of isopropyl alcohol and myristic acid. 
The isopropyl component is a propane derivative; mirystic acid is a fatty acid common in plant sources such as nutmeg and palm seeds. 


Isopropyl Myristate (IPM) possesses several unique characteristics which make it a valuable additive in many cosmetics and pharmaceutical products. 
Certainly one of the most significant of these is the oil's ease of absorption by the skin. 
Used as an emollient in creams and lotions, Isopropyl Myristate (IPM) ensures deep, quick penetration for these preparations.


This deep penetrating characteristic does have a downside however; extensive use of products containing the oil may lead to pore clogging. 
Isopropyl Myristate (IPM) still remains a valuable absorption carrier, though, and is common component of moisturizers, bath oils, and lotions. 
Although itself an oil, Isopropyl Myristate (IPM) also reduces greasiness in cosmetics. 


When added to lip products and creams, Isopropyl Myristate (IPM) lends the cosmetics a slick, sheer texture without any greasy feel.
Isopropyl Myristate (IPM) is also a common ingredient in pharmaceutical formulations. 
Isopropyl Myristate (IPM) is often used as a non-pesticide alternative for treating head lice infestations. 


Isopropyl Myristate (IPM) destroys the wax layer which insulates the lice and causes death by dehydration. 
Isopropyl Myristate (IPM) is also effective at controlling oral bacteria and is used in several mouthwash products.


Isopropyl Myristate (IPM) is a synthetic oil composed of isopropyl alcohol, a propane derivative, and myristic acid, a naturally occurring fatty acid. 
Isopropyl Myristate (IPM)'s a common cosmetic component in a wide range of beauty products, including aftershaves, antiperspirants, and anti-ageing lotions.

USES and APPLICATIONS of ISOPROPYL MYRISTATE (IPM):
Isopropyl Myristate (IPM) is commonly used in various industries, particularly in cosmetics and pharmaceuticals, due to its beneficial properties.
Isopropyl Myristate (IPM) is a polar emollient and is used in cosmetic and topical pharmaceutical preparations where skin absorption is desired. 
Isopropyl Myristate (IPM) is also used as a treatment for head lice.


Isopropyl Myristate (IPM) is also in flea and tick killing products for pets.
Isopropyl Myristate (IPM) is used to remove bacteria from the oral cavity as the non-aqueous component of the two-phase mouthwash product "Dentyl pH".
Isopropyl Myristate (IPM) is also used as a solvent in perfume materials, and in the removal process of prosthetic make-up.


Industrial Applications: Isopropyl Myristate (IPM) is used as a lubricant and in the formulation of various industrial products.
Isopropyl Myristate (IPM) is a fast spreading emollient suitable for all cosmetic applications.
Isopropyl Myristate (IPM) can be added to formulas as is, add to oil phase. 


Typical use level of Isopropyl Myristate (IPM) is 1-20%. 
Required HLB value of Isopropyl Myristate (IPM) is 11.5. 
Isopropyl Myristate (IPM) is used for external use only.


Isopropyl Myristate (IPM) is used Creams, lotions, hand creams, shampoo, shower gels, makeup removers, powders and foundations.
Isopropyl Myristate (IPM) is used raw material for spin finishes and oiling agent for textile, Rubber processing agent, Plastic lubricant, Paint additive, Ink additive, and Cosmetic base. 


Isopropyl Myristate (IPM) is used additives for pharmaceuticals.
Isopropyl Myristate (IPM) is a fatty acid ester which is used as solvent in water-in-oil emulsion, oils and fatty based ointments.
The use of IPM is recommended in the Sterility Test chapter of the European, Japanese and United States Pharmacopoeia (EP, 2.6.13, JP, 4.06 and USP, 71) as diluent for oils and oily solutions, as well as for ointments and creams. Indeed, its solvent properties improve the filterability of these samples.


Isopropyl Myristate (IPM) is known as a penetration enhancer for topical preparations. 
Isopropyl Myristate (IPM) is a waterclear, low viscous oily liquid with a very good spreading capacity on the skin.
Isopropyl Myristate (IPM) is mainly used in cosmetics as an oilcomponent for emulsions, bath oils and as a solvent for active substances.


Isopropyl Myristate (IPM) is an emollient in cosmetic and pharmaceutical bases.
Isopropyl Myristate (IPM) is an emollient, moisturizer, binder, and skin softener that also assists in product penetration. 
An ester of myristic acid, Isopropyl Myristate (IPM) is naturally occurring in coconut oil and nutmeg. 


Although Isopropyl Myristate (IPM) is generally considered comedogenic, some ingredient manufacturers clearly specify non-comedogenicity on their data sheets.
Isopropyl Myristate (IPM) is used in cosmetic and topical medicinal Preparations where good absorption through the skin is desired. 


Isopropyl Myristate (IPM) is used as an emulsifier, emollient, thickening agent, lubricant and moisturiser in cosmetic, personal care and pharmaceutical products.
Isopropyl Myristate (IPM) is used in the oil phase of your formula to help your product absorb quicker and easier, as well as helping your product spread and glide smoothly on application. 


Isopropyl Myristate (IPM) is also commonly used in cosmetic manufacturing to make finished products feel smoother rather than oily.
Widely used in products such as creams & lotions, shampoos, shower gels, bath & baby oils, aftershaves, powders, foundations and makeup removers.
Application of Isopropyl Myristate (IPM): Treatment / Conditioner, Cleansing, Milk / Cream / Serum, Foundation / Make-up Base, and Suncare.


Isopropyl Myristate (IPM) is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Isopropyl Myristate (IPM) is used in the following products: washing & cleaning products, lubricants and greases, textile treatment products and dyes, adhesives and sealants, polymers and polishes and waxes.


Release to the environment of Isopropyl Myristate (IPM) can occur from industrial use: in the production of articles.
Other release to the environment of Isopropyl Myristate (IPM) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.


Release to the environment of Isopropyl Myristate (IPM) can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal) and of articles where the substances are not intended to be released and where the conditions of use do not promote release. 


Other release to the environment of Isopropyl Myristate (IPM)is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment). 


Isopropyl Myristate (IPM) can be found in complex articles, with no release intended: vehicles and vehicles not covered by End of Life Vehicles (ELV) directive (e.g. boats, trains, metro or planes). 
Isopropyl Myristate (IPM) is used in the following products: washing & cleaning products and polishes and waxes.


Isopropyl Myristate (IPM) can be found in products with material based on: metal (e.g. cutlery, pots, toys, jewellery), metal used for large surface area articles (e.g. construction and building materials used for roof sheets, pipes), plastic (e.g. food packaging and storage, toys, mobile phones) and wood (e.g. floors, furniture, toys).


Isopropyl Myristate (IPM) is used in the following areas: formulation of mixtures and/or re-packaging.
Isopropyl Myristate (IPM) is used for the manufacture of: chemicals and .
Other release to the environment of Isopropyl Myristate (IPM) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.


Isopropyl Myristate (IPM) is used in the following products: washing & cleaning products, polymers, lubricants and greases, metal working fluids, cosmetics and personal care products and textile treatment products and dyes.
Release to the environment of Isopropyl Myristate (IPM) can occur from industrial use: formulation of mixtures and formulation in materials.


Isopropyl Myristate (IPM) is used in the following products: washing & cleaning products, metal surface treatment products and lubricants and greases.
Isopropyl Myristate (IPM) is used in the following areas: formulation of mixtures and/or re-packaging.
Isopropyl Myristate (IPM) is used for the manufacture of: chemicals.


Release to the environment of Isopropyl Myristate (IPM) can occur from industrial use: in processing aids at industrial sites and in the production of articles.
Release to the environment of Isopropyl Myristate (IPM) can occur from industrial use: manufacturing of the substance.


Isopropyl Myristate (IPM) is a high-performance lightweight emollient widely used in the personal care, skincare, and cosmetic industries. 
Derived from the esterification of isopropyl alcohol and myristic acid, Isopropyl Myristate (IPM) is valued for its ability to reduce the greasy feel of formulations, improve absorption, and enhance the sensory experience.


Isopropyl Myristate (IPM) is a versatile, non-greasy, and fast-absorbing ingredient that acts as an excellent carrier for active ingredients. 
Suitable for a wide range of applications, including skincare, haircare, and industrial formulations, Isopropyl Myristate (IPM) is the go-to solution for achieving high-performance, consumer-friendly products.


Isopropyl Myristate (IPM) improves spreadability, making formulations feel lighter and more luxurious. 
Isopropyl Myristate (IPM) is used in cosmetic preparations as an emollient and in perfumes as a solvent. 


Isopropyl Myristate (IPM) is also used in preparations against lice for humans and against fleas and ticks for animals.
Isopropyl Myristate (IPM) is most commonly found in after-shave products, shampoos, bath oils, antiperspirants and deodorants, oral hygiene products and various body lotions and skin creams.


A unique property of Isopropyl Myristate (IPM) is its ability to reduce the greasy feeling caused by its high oil content. 
Isopropyl Myristate (IPM) is easily absorbed into the skin and ensures rapid penetration of product ingredients. 
Isopropyl Myristate (IPM) is insoluble in water.


At a concentration of more than 5% Isopropyl Myristate (IPM) can clog pores (it is comedogenic).
Isopropyl Myristate (IPM) is a moisturizer with polar characteristics used in cosmetics and topical medical preparations to ameliorate the skin absorption. 
Isopropyl Myristate (IPM) has been largely studied and impulsed as a skin penetration enhancer.


At the moment the primary usage for which Isopropyl Myristate (IPM) is formally indicated is as the active ingredient in a non-prescription pediculicide rinse
Isopropyl Myristate (IPM) is used to reduce the greasiness of lotion bars, whipped butters and emulsions. 


Isopropyl Myristate (IPM) is used in the fragrance world to dilute materials. 
Isopropyl Myristate (IPM) is used in diffusers. 


-Applications of Isopropyl Myristate (IPM) in Perfumery:
*Perfume Oils: Isopropyl Myristate (IPM) is used as a diluent in perfume oils to make the fragrance more spreadable without altering its scent profile significantly.

*Eau de Toilette and Eau de Parfum: 
Isopropyl Myristate (IPM) helps in the formulation of these products by ensuring a smooth application and enhanced fragrance delivery.

*Solid Perfumes: 
Isopropyl Myristate (IPM) can be used in solid perfume formulations to improve texture and ease of application.

*Body Sprays and Mists: 
Isopropyl Myristate (IPM) is included to enhance the feel and performance of the product when sprayed onto the skin.


-Applications of Isopropyl Myristate (IPM) in Room Sprays:
Why Isopropyl Myristate (IPM) is Used in Room Sprays:

*Solvent: 
Isopropyl Myristate (IPM) helps dissolve fragrance oils, allowing them to mix well with other solvents or carriers like alcohol or water. 
Isopropyl Myristate (IPM) also helps in reducing the greasy feel of some oils.

*Improves Sprayability: 
Isopropyl Myristate (IPM) makes the spray apply more evenly, reducing the likelihood of clogging the spray mechanism or leaving residue on surfaces.

*Quick Evaporation: 
Isopropyl Myristate (IPM) evaporates quickly, helping to disperse the fragrance into the air without lingering residue.


-Cosmetics uses of Isopropyl Myristate (IPM):
*Moisturizers and Lotions: Isopropyl Myristate (IPM) enhances skin feel and spreadability.
*Hair Care Products: Isopropyl Myristate (IPM) is used in conditioners and treatments to improve texture.
*Makeup: Incorporated into foundations, powders, and lip products for a smooth application.


-Pharmaceuticals uses of Isopropyl Myristate (IPM):
*Topical Medications: Isopropyl Myristate (IPM) enhances the delivery of active ingredients through the skin.
*Ointments and Creams: Isopropyl Myristate (IPM) improves consistency and application.


-Personal Care uses of Isopropyl Myristate (IPM):
*Deodorants: Isopropyl Myristate (IPM) acts as a solvent and carrier for active ingredients.
*Sunscreens: Isopropyl Myristate (IPM) helps distribute UV filters evenly.


-Skincare uses of Isopropyl Myristate (IPM):
*Moisturizing creams and lotions
*Anti-aging serums and treatments
*Sunscreens and after-sun products
*Body oils and massage formulations


-Haircare uses of Isopropyl Myristate (IPM):
*Conditioners and hair masks for enhanced softness and shine
*Leave-in treatments for lightweight hydration
*Scalp care products


-Cosmetics uses of Isopropyl Myristate (IPM):
*Foundations, primers, and BB creams for a lightweight, silky feel
*Lip balms and glosses for smooth application
*Makeup removers


-Personal Care uses of Isopropyl Myristate (IPM):
*Deodorants for a smooth glide
*Shaving creams and aftershaves for reduced irritation
*Cleansers and scrubs for enhanced skin-feel


-Industrial Applications of Isopropyl Myristate (IPM):
*Isopropyl Myristate (IPM) is used as a solvent and dispersing agent in pharmaceutical formulations
*Carrier for fragrances and essential oils
*Additive in biodegradable lubricants and greases

PHARMACEUTICAL APPLICATIONS OF ISOPROPYL MYRISTATE (IPM):
Isopropyl Myristate (IPM) is a nongreasy emollient that is absorbed readily by the skin. 
Isopropyl Myristate (IPM) is used as a component of semisolid bases and as a solvent for many substances applied topically. 

Applications of Isopropyl Myristate (IPM) in topical pharmaceutical and cosmetic formulations include bath oils; make-up; hair and nail care products; creams; lotions; lip products; shaving products; skin lubricants; deodorants; otic suspensions; and vaginal creams. 
For example, Isopropyl Myristate (IPM) is a self-emulsifying component of a proposed cold cream formula, which is suitable for use as a vehicle for drugs or dermatological actives; Isopropyl Myristate (IPM) is also used cosmetically in stable mixtures of water and glycerol.

Isopropyl Myristate (IPM) is used as a penetration enhancer for transdermal formulations, and has been used in conjunction with therapeutic ultrasound and iontophoresis.
Isopropyl Myristate (IPM) has been used in a water-oil gel prolonged-release emulsion and in various microemulsions. 

Such microemulsions may increase bioavailability in topical and transdermal applications. 
Isopropyl Myristate (IPM) has also been used in microspheres, and significantly increased the release of drug from etoposide-loaded microspheres.
Isopropyl Myristate (IPM) is used in soft adhesives for pressuresensitive adhesive tapes.

BENEFITS OF ISOPROPYL MYRISTATE (IPM):
*Enhances Fragrance Longevity: By improving the absorption into the skin, IPM can help fragrances last longer.
*Improves Skin Feel: Isopropyl Myristate (IPM) ensures that the product feels pleasant and non-oily upon application.
*Versatile Solvent: Isopropyl Myristate (IPM) can dissolve a wide range of fragrance oils, making it a flexible ingredient for perfumers.

HOW TO USE ISOPROPYL MYRISTATE (IPM) IN ROOM SPRAYS:
Ingredients:
Isopropyl Myristate (IPM): Acts as a carrier solvent.
Fragrance Oils or Essential Oils: The main scent component.

Ethanol or Isopropyl Alcohol: Helps with evaporation and solubilizes the oils.
Distilled Water (Optional): If you’re making a water-based spray.
Preservatives (Optional): If water is included, you may need a preservative to prevent bacterial growth.


Steps:
Mix Fragrance with Isopropyl Myristate (IPM): 
Start by combining your fragrance or essential oil with Isopropyl Myristate. 
The amount of Isopropyl Myristate (IPM) depends on the formulation, but typically, around 5-10% of the total solution is used.


Add Alcohol: 
If you're using alcohol (e.g., ethanol or isopropyl alcohol) as part of the formulation, mix it with the IPM-fragrance blend. 
The alcohol helps the fragrance evaporate and diffuse more effectively.


Blend Thoroughly: 
Stir the mixture well to ensure all components are fully combined. 
This step is critical for avoiding separation.


Optional: Add Water: 
If you’re creating a water-based spray, add distilled water to the blend, but ensure you include a preservative to prevent microbial growth.


Bottle and Use: 
Pour the mixture into a fine mist spray bottle. 
Shake before each use to ensure consistent spraying.


Example Room Spray Formula:
70% Ethanol or Isopropyl Alcohol
10-15% Fragrance or Essential Oil
5-10% Isopropyl Myristate (IPM)
Water (optional, in case of a lighter spray formulation)

WHAT IS ISOPROPYL MYRISTATE (IPM) USED FOR?
Isopropyl Myristate (IPM) is a texture enhancer and emollient as used in cosmetics. 
Isopropyl Myristate (IPM) can also help to enhance the absorption of ingredients in a cosmetic formula.


*Skin care: 
Isopropyl Myristate (IPM) works as an emollient, thickener, and a lubricant in beauty products. 
Isopropyl Myristate (IPM) locks in the hydration, and enhances the penetration of other ingredients in the formulation.

Isopropyl Myristate (IPM) is an effective agent for solubilizing lanolin. 
Therefore, Isopropyl Myristate (IPM) is used as a solubilizing, spreading, and penetrating agent in anhydrous skin lubricating lotions with high lanolin content. 

Isopropyl Myristate (IPM) leaves the skin soft and smooth without an oily surface film. 
Isopropyl Myristate (IPM) can even reduce the heavy, greasy feel in products with high oil content. 
Isopropyl Myristate (IPM)'s also fast-spreading meaning that it gives the formula a good, nice slip


*Hair care: 
Isopropyl Myristate (IPM) works as a hydrating agent, emollient, and enhancer. 
Isopropyl Myristate (IPM) hydrates the hair and the scalp and enhances the penetration of other ingredients in the formulation. 

Isopropyl Myristate (IPM) is not recommended for particularly thin hair, as it can make it appear greasy, or an oily scalp or hair, as it can lead to clogged pores.

ORIGIN OF ISOPROPYL MYRISTATE (IPM):
Isopropyl Myristate (IPM) is commercially produced by distillation, before which the esterification of myristic acid and isopropanol is carried out, and the resulting alkali is refined to neutralize the catalyst, and the product is then distilled to obtain isopropyl myristate.

WHAT DOES ISOPROPYL MYRISTATE (IPM) DO IN A FORMULATION?
*Emollient
*Perfuming
*Skin conditioning
*Viscosity controlling

SAFETY PROFILE OF ISOPROPYL MYRISTATE (IPM):
Isopropyl Myristate (IPM) is determined safe for use in cosmetics according to the Cosmetics Ingredient Review (CIR) panel.

ALTERNATIVES OF ISOPROPYL MYRISTATE (IPM):
*C1215 ALKYL BENZOATE, 
*COCOCAPRYLATE, 
*ISODODECANE

KEY FEATURES AND BENEFITS OF ISOPROPYL MYRISTATE (IPM):
*Lightweight and Non-Greasy Feel:
Reduces the oily residue in formulations, leaving a silky-smooth finish on the skin.

*Enhances Absorption:
Helps active ingredients penetrate the skin more effectively, increasing efficacy.

*Improves Spreadability:
Provides a smooth and even application, making formulations easier to apply.

*Versatile Compatibility:
Compatible with oils, esters, and silicones, making it ideal for various formulations.

*Non-Comedogenic:
Does not clog pores, making it suitable for facial products and acne-prone skin.

*Eco-Friendly and Biodegradable:
Derived from renewable sources, ensuring sustainability for environmentally conscious brands.

*Stabilizer:
Acts as a stabilizer in formulations, ensuring long-term product stability and consistency.

DESCRIPTION OF ISOPROPYL MYRISTATE (IPM):
Ester of isopropyl alcohol and myristic acid (vegetable-derived). 
Low viscosity fluid non-greasy emollient, tolerates wide pH range, compatible with most surfactants. 
Thanks to its low viscosity and density, Isopropyl Myristate (IPM) has a high spreadability. 
Specific gravity of Isopropyl Myristate (IPM) is 0.85 (at 20°C).

BENEFITS OF ISOPROPYL MYRISTATE (IPM):
*Superior emollient for non-greasy bath, body and baby oils
*Lubricant and compression aid for pressed powders
*Light & non-tacky emollient for creams and lotions. 
*Readily adsorbed by the skin
*When used at high concentrations it gently lifts makeup and surface dirt
*Gives gloss and shine to hair
*Resistant to oxidation (does not become rancid)
*Widely used as diluent for fragrance oils.

BENEFITS AND APPLICATIONS OF ISOPROPYL MYRISTATE (IPM):
The use of Isopropyl Myristate (IPM) in skincare products has the advantage of assisting in the dissolution of other skincare components, enabling them to be dispersed uniformly throughout the formulation.

Isopropyl Myristate (IPM) is especially beneficial for dry and flaky skin as it acts as a brilliant emollient and helps in softening and smoothing your skin. 
Isopropyl Myristate (IPM) also eliminates germs, which is one of its key advantages. 

As a result, Isopropyl Myristate (IPM) is frequently used in hand sanitizers. 
This, together with the fact that isopropyl myristate evaporates quickly, makes Isopropyl Myristate (IPM) an excellent component in both skincare and hand sanitizer products.

Isopropyl Myristate (IPM) works as an emollient for your DIY formulation, which increases the product’s spreadability and improves texture.
Isopropyl Myristate (IPM) is special in that it can improve the penetration of other substances.
Isopropyl Myristate (IPM) is incredibly necessary when formulating and making cosmetically elegant goods.

HOW ISOPROPYL MYRISTATE (IPM) WORKS:
Isopropyl Myristate (IPM) works by attracting moisture from the air and fixing it in the deep layers of skin and scalp.
Isopropyl Myristate (IPM) works by creating a preventive barrier that locks moisture into the skin and increases the moisture retention capacity.

CONCENTRATION AND SOLUBILITY OF ISOPROPYL MYRISTATE (IPM):
Isopropyl Myristate (IPM) is recommended that it should be used at a concentration of 1 to 20%.
Isopropyl Myristate (IPM) is soluble in most solvents but is insoluble in water.

HOW TO USE ISOPROPYL MYRISTATE (IPM):
Prepare the oil and water phases of your formulation separately.
Heat the water and oil phase using a double boiler.
Add our isopropyl myristate to the heated oil phase with constant stirring.
Blend both the phases using a mini-mixer until the required consistency is not obtained. 

PROPERTIES OF ISOPROPYL MYRISTATE (IPM):
Cosmetic and pharmaceutical use of Isopropyl Myristate (IPM): Oil base with low viscosity, good adaptation to skin. 
Isopropyl Myristate (IPM) is colorless no odor. 

Isopropyl Myristate (IPM) is suitable for cream-milk lotion, emollient and shampoo.
Isopropyl Myristate (IPM) is a slightly yellowish, transparent liquid.

Isopropyl Myristate (IPM) can be dissolved in oil-based solvents and some organic compounds.
Isopropyl Myristate (IPM) has a skin softening and smoothing potential. 

Isopropyl Myristate (IPM) helps moisturize the skin. 
Isopropyl Myristate (IPM) supports the protection of the skin against environmental factors. 

Isopropyl Myristate (IPM) ensures the homogeneous mixing of other ingredients and increases the stability of the formulation.
The usage rate of Isopropyl Myristate (IPM) varies according to the agent of the product used.

Lotions: 1% to 10%
Creams: 1% to 20%
Lip balms: 1% to 5%
Hair care products: 1% to 10%
Make-up products: Can be used between 1% and 10%.

FUNCTIONS OF ISOPROPYL MYRISTATE (IPM) IN PERFUMERY:
*Carrier and Solvent: 
Isopropyl Myristate (IPM) can act as a carrier or solvent for fragrance oils, helping to dissolve and distribute the aromatic compounds evenly in the formulation.

*Improved Absorption: 
Isopropyl Myristate (IPM) helps in enhancing the absorption of the fragrance into the skin, making the scent more pronounced and long-lasting.

*Non-Greasy Feel: 
Isopropyl Myristate (IPM) imparts a lightweight, non-greasy feel, which is desirable for perfumery products applied directly to the skin.

*Stabilization: 
Isopropyl Myristate (IPM) can help stabilize the fragrance formulation, maintaining its integrity and preventing separation of components.

CHEMICAL PROPERTIES OF ISOPROPYL MYRISTATE (IPM):
Isopropyl Myristate (IPM) is a colorless and odorless liquid with a faint odor, and miscible with vegetable oil. 
Isopropyl Myristate (IPM) is not easy to be either hydrolyzed or become rancid. 

The refractive index nD20 is 1.435~1.438, and the relative density (20&deg;C) is 0.85~0.86. 
Isopropyl Myristate (IPM) is used in many applications, including pharma, food and personal care product manufacturing.

Content Analysis
Weight 1.5 g sample. 
Then Isopropyl Myristate (IPM) is determined by the method ester assay (OT-18). 

The equivalent factor (e) in the calculation is 135.2. 
Or Isopropyl Myristate (IPM) is determined by a non-polar column method of gas chromatography (GT-10-4).

PRODUCTION METHOD OF ISOPROPYL MYRISTATE (IPM):
Isopropyl Myristate (IPM) is a product of esterification of myristic acid derived from re-steamed coconut coil with isopropyl alcohol.

(1)  200 kg myristic acid and 450 kg isopropyl alcohol were added into the reaction vessel in turn. 
After mixing, 360 kg sulfuric acid (98%) was added. 

The reaction mixture was heated to reflux for 10 hours. 
Isopropyl alcohol was then recovered, washed with ice water, and neutralized with Na2CO3 aqueous solution (10%). 

Under normal pressure, isopropyl alcohol and water were distilled. 
While under reduced pressure, isopropyl myristate was distilled (185°C/1.0kPa~195°C/2.7kPa).


(2) 90 kg isopropyl alcohol was added into the reaction vessel and then sulfuric acid as catalyst, with 5% of the total amount, was added. 
During mixing, 228 kg myristic acid was added slowly. 
The mixture was heated to reflux and water was continuously separated. 

Until no water was separated, the reaction temperature was reduced and probe was obtained to measure the acid value. 
When the acid value reached 1.5 mg KOH/g, the reaction was completed. 

Alkali was then added for neutralization. 
After the removal of water under reduced pressure, the pressure was further reduced for dealcoholization until the acid value was 0.05~1.0 mg KOH/g. 
The final product is then isopropyl myristate.

CHEMICAL PROPERTIES OF ISOPROPYL MYRISTATE (IPM):
Pure Isopropyl Myristate (IPM) is virtually odorless, very slightly fatty, but not rancid
Isopropyl Myristate (IPM) is a colourless liquid of low viscosity
Isopropyl Myristate (IPM) is a clear, colorless, practically odorless liquid of low viscosity that congeals at about 5°C. 
Isopropyl Myristate (IPM) consists of esters of propan-2-ol and saturated high molecular weight fatty acids, principally myristic acid.

OCCURRENCE OF ISOPROPYL MYRISTATE (IPM):
Reported found in kumquat peel oil, papaya, starfruit, plum brandy, coriander seed and loquat

BIOCHEM/PHYSIOL ACTIONS OF ISOPROPYL MYRISTATE (IPM):
Isopropyl Myristate (IPM) (myristic acid isopropyl ester) is used to change the physicochemical characteristics of microsheres such as poly(lactic-co-glycolic acid) (PLGA) microspheres. 
Isopropyl Myristate (IPM) is used as a oil phase component in the formulaton of microemulsion systems.

PHARMACOLOGY OF ISOPROPYL MYRISTATE (IPM):
Isopropyl Myristate (IPM) is used in pharmaceutical preparations because it improves solubility and increases absorption through the skin. 
External uses of Isopropyl Myristate (IPM) include a non-irritating iodine preparation for disinfecting the skin and aerosol bactericidal preparations for feminine hygiene use without irritation of the skin and mucous membranes. 

Preparations for internal use include oral steroid formulations and anaesthetic injection solutions.
Veterinary medications containing isopropyl myristate include oral or parenteral compositions for lungworm infections and a spray formulation for bovine udders to treat mastitis, combat infection and improve the general skin condition. 

PRODUCTION METHODS OF ISOPROPYL MYRISTATE (IPM):
Isopropyl Myristate (IPM) may be prepared either by the esterification of myristic acid with propan-2-ol or by the reaction of myristoyl chloride and propan-2-ol with the aid of a suitable dehydrochlorinating agent. 
A high-purity material is also commercially available, produced by enzymatic esterification at low temperature.

PREPARATION OF ISOPROPYL MYRISTATE (IPM):
By conventional esterification of isopropanol with myristic acid

PROPERTIES OF ISOPROPYL MYRISTATE (IPM):
*Emollient: 
Isopropyl Myristate (IPM) helps to soften and smooth the skin.

*Penetration Enhancer: 
Isopropyl Myristate (IPM) facilitates the absorption of other ingredients through the skin.

*Non-Greasy Feel: 
Isopropyl Myristate (IPM) provides a lightweight and non-oily texture to formulations.

*Solvent: 
Isopropyl Myristate (IPM) can dissolve certain ingredients, improving the formulation and stability of products.

SYNTHESIS OF ISOPROPYL MYRISTATE (IPM):
Isopropyl Myristate (IPM) is synthesized by conventional esterification of iso-Propanol with Myristic acid.

METABOLISM OF ISOPROPYL MYRISTATE (IPM):
Higher molecular weight aliphatic esters are thought to be readily hydrolysed to the corresponding alcohols and acids which are then metabolized; isopropyl myristate is undoubtedly hydrolysed to normal metabolic products. 
When myristic acid (as the ethyl ester) was fed to dogs,

STORAGE OF ISOPROPYL MYRISTATE (IPM):
Isopropyl Myristate (IPM) is resistant to oxidation and hydrolysis, and does not become rancid. 
Isopropyl Myristate (IPM) should be stored in a well-closed container in a cool, dry place and protected from light.

INCOMPATIBILITIES OF ISOPROPYL MYRISTATE (IPM):
When Isopropyl Myristate (IPM) comes into contact with rubber, there is a drop in viscosity with concomitant swelling and partial dissolution of the rubber; contact with plastics, e.g. nylon and polyethylene, results in swelling. 
Isopropyl Myristate (IPM) is incompatible with hard paraffin, producing a granular mixture. 
Isopropyl Myristate (IPM) is also incompatible with strong oxidizing agents.

ALTERNATIVES OF ISOPROPYL MYRISTATE (IPM):
*C1215 ALKYL BENZOATE, 
*COCOCAPRYLATE, 
*ISODODECANE

KEY PROPERTIES OF ISOPROPYL MYRISTATE (IPM):
*Water insoluble
*Clear, colourless, oil-like
*Good skin absorption in moisturisers
*Emollient
*Halal
*Kosher
*Non-GMO
*RSPO MB available

PHYSICAL and CHEMICAL PROPERTIES of ISOPROPYL MYRISTATE (IPM):
Melting point: ~3 °C (lit.)
Boiling point: 193 °C/20 mmHg (lit.)
Density: 0.85 g/mL at 25 °C (lit.)
Vapor pressure: <1 hPa (20 °C)
Refractive index: n20/D 1.434 (lit.)
FEMA: 3556 | ISOPROPYL MYRISTATE
Flash point: >230 °F
Storage temp.: 2-8°C
Solubility: <0.05mg/l
Form: Liquid

Specific Gravity: 0.855 (20/4℃)
Color: Clear
Odor: Odorless
Viscosity: 4.8cp (25°C)
Water Solubility: Miscible with alcohol. 
Immiscible with water and glycerol.
Merck: 14,5215
JECFA Number: 311
BRN: 1781127
Stability: Stable. 
Incompatible with strong oxidizing agents.

InChIKey: AXISYYRBXTVTFY-UHFFFAOYSA-N
LogP: 7.71
Substances Added to Food (formerly EAFUS): ISOPROPYL MYRISTATE
CAS DataBase Reference: 110-27-0 (CAS DataBase Reference)
EWG's Food Scores: 1
FDA UNII: 0RE8K4LNJS
NIST Chemistry Reference: Isopropyl Myristate (110-27-0)
EPA Substance Registry System: Isopropyl myristate (110-27-0)
Cosmetics Info: Isopropyl Myristate
Ingredients: Isopropyl Myristate
INCI Name: Isopropyl Myristate

Origin: Natural - Vegetable derived
Solubility: Soluble in Oil. Insoluble in Glycerine and Water.
Appearance: Clear Liquid
Cas No: 110-27-0
EINECS No: 203-751-4
Molecular formula: CH3(CH2)12COOC­H(CH3)2
Appearance: Light yellow / clear oily liquid
Other names: Tetradecanoic acid, 1-methylethyl ester; 
Myristic acid isopropyl ester: IPM; 
propan-2-yl tetradecanoate; Estergel;
Molecular weight: 270.46
Acid value: 0.5 max

Specific gravity: 0.85
Melting Point: 3-5 oC
Boiling Point: 167 oC
Flash Point: 152 oC
Heavy metal: 0.0005% max
Insoluble in: Water.
Soluble in: Most organic solvents
Refractive index: 1.44
Vapour pressure: 9.35X10-5 mm Hg at 25 C
Molecular Weight: 270.5 g/mol
XLogP3-AA: 7.2

Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 14
Exact Mass: 270.255880323 g/mol
Monoisotopic Mass: 270.255880323 g/mol
Topological Polar Surface Area: 26.3Ų
Heavy Atom Count: 19
Formal Charge: 0
Complexity: 199
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Chemical formula: C17H34O2
Molar mass: 270.457 g·mol−1
Density: 0.85 g/cm3
Boiling point: 167 °C (333 °F; 440 K) at 9 mmHg
CAS number: 110-27-0
EC number: 203-751-4
Hill Formula: C₁₇H₃₄O₂
Molar Mass: 270.45 g/mol

Boiling point: 140 °C (3 hPa)
Density: 0.85 g/cm3 (20 °C)
Flash point: >150 °C
Ignition temperature: >300 °C
Vapor pressure: <1 hPa (20 °C)
Solubility: <0.05 mg/l
Boiling Point: 192-193°C
Melting Point: 2-3°C
Solubility: Soluble in benzyl benzoate, 
ethyl lactate, paraffin oil
Insoluble in water

Physical state: liquid
Color: No data available
Odor: No data available
Melting point/freezing point:
Melting point/range: 3 °C - lit.
Initial boiling point and boiling range: 193 °C at 27 hPa - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point > 150 °C - open cup

Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity 
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient:
n-octanol/water: No data available
Vapor pressure: No data available
Density: 0,85 g/cm3 at 25 °C - lit.

Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Acid Value (mg KOH/g): 0.5 Max
Saponification Value (mg KOH/g): 206-211
Color (APHA): 30 Max
Moisture Content (%): 0.1 Max
Ash Content (%): 0.1 Max
Peroxide Value (meq/Kg): 0.6 Max

Viscosity (mPa.s) 20℃: 5-6
Density (g/cm3) 20℃: 0.852-0.855
Refractive Index 20℃: 1.434-1.437
APPEARANCE AT 20°: Clear mobile liquid / solid 
COLOR: Colorless 
ODOR: Nearly odorless, oily, fatty 
OPTICAL ROTATION (°): 0 / 0 
DENSITY AT 20°C (G/ML)): 0,848 - 0,856 
REFRACTIVE INDEX ND20: 1,4320 - 1,4370 
FLASHPOINT (°C): 155 
SOLUBILITY: Insoluble in water 
ASSAY (% GC): > 98 
ACID VALUE (MG KOH/G): < 0,5 

Appearance: A colorless or slightly yellow oily liquid
Ester content %: ≥98
Acid value(mg KOH/g): ≤0.5
Hazen(Color): ≤30
Refractive index: 1.434-1.438
Specific gravity(20℃): 0.850-0.855
Appearance: colorless clear oily liquid (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.84000 to 0.86000 @ 25.00 °C.
Pounds per Gallon - (est).: 6.990 to 7.156

Refractive Index: 1.42800 to 1.44300 @ 20.00 °C.
Melting Point: 2.00 to 3.00 °C. @ 760.00 mm Hg
Boiling Point: 192.00 to 193.00 °C. @ 20.00 mm Hg
Acid Value: 1.00 max. KOH/g
Saponification Value: 207.00
Vapor Pressure:    0.000329 mmHg @ 25.00 °C. (est)
Flash Point: > 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w): 7.253 (est)
Shelf Life: 24.00 month(s) or longer if stored properly.
Storage: store in cool, dry place in tightly sealed containers, 
protected from heat and light.

Soluble in: amyris wood oil,
benzyl benzoate, benzyl salicylate,
clove leaf oil, deluent for candle fragrances,
ethyl acetoacetate, ethyl lactate,
paraffin oil, water, 0.01354 mg/L @ 25 °C (est),
Insoluble in: water,
Similar Items:note
isoamyl myristate, butyl myristate, isobutyl myristate, 
ethyl myristate, hexyl myristate
Boiling point: 140 °C (3 hPa)
Density: 0.85 g/cm3 (20 °C)
Flash point: >150 °C

Ignition temperature: >300 °C
Vapor pressure: <1 hPa (20 °C)
Solubility: <0.05 mg/l
IUPAC Name: propan-2-yl tetradecanoate
Molecular Weight: 270.45
Molecular Formula: C17H34O2
Canonical SMILES: CCCCCCCCCCCCCC(=O)OC(C)C
InChI: InChI=1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3
InChIKey: AXISYYRBXTVTFY-UHFFFAOYSA-N
Boiling Point: 167 °C at 9 mmHg
Melting Point: -5ºC
Flash Point: 29.6 dyne/cm Density: 0.864 g/cm³
Purity: 98%+

Density: 0.853 g/cm3
Solubility: Soluble in chloroform (slightly), ethyl acetate (slightly).
Appearance: Clear colorless oil
Storage: Room Temperature
EINECS: 203-751-4
Hazard Class: 6.1
Hazard Codes: Xi
HS Code: 29159080
Log P: 5.63910
MDL: MFCD00008982
PSA: 26.3
Refractive Index: 1.434-1.436

Risk Statements: R36/37/38
RTECS: XB8600000
Safety Statements: S26-S36
Stability: Stable. 
Vapor Pressure: 0.000329mmHg at 25°C
Molecular Weight: 270.5 g/mol
XLogP3-AA: 7.2
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 14
Exact Mass: 270.255880323 g/mol
Monoisotopic Mass: 270.255880323 g/mol

Topological Polar Surface Area: 26.3Ų
Heavy Atom Coun: 19
Formal Charge: 0
Complexity: 199
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Appearance: colorless clear oily liquid (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.84000 to 0.86000 @ 25.00 °C.
Pounds per Gallon - (est).: 6.990 to 7.156
Refractive Index: 1.42800 to 1.44300 @ 20.00 °C.
Melting Point: 2.00 to 3.00 °C. @ 760.00 mm Hg
Boiling Point: 192.00 to 193.00 °C. @ 20.00 mm Hg
Acid Value: 1.00 max. KOH/g
Saponification Value: 207.00
Vapor Pressure:    0.000329 mmHg @ 25.00 °C. (est)
Flash Point: > 230.00 °F. TCC ( > 110.00 °C. )

logP (o/w): 7.253 (est)
Shelf Life: 24.00 month(s) or longer if stored properly.
Storage: store in cool, dry place in tightly sealed containers, 
protected from heat and light.
Soluble in: amyris wood oilbenzyl benzoatebenzyl salicylate
clove leaf oil
deluent for candle fragrances
ethyl acetoacetate
ethyl lactate
paraffin oil
water, 0.01354 mg/L @ 25 °C (est)
Insoluble in:
water

IUPAC: Propan-2-yl tetradecanoate
INCI: ISOPROPYL MYRISTATE
CAS: 110-27-0
Molar mass: 270,457 g/mol
Density: 0,85 g/cm3 (20 °C)
Solubility: Miscible with water, benzene, chloroform, ethanol, ether, glycerin.
Soluble in acetone.
Molecular Weight: 270.45
Formula: C17H34O2
CAS No.: 110-27-0
Appearance: Liquid (Density: 0.85 g/cm3)
Color: Colorless to light yellow

SMILES: CCCCCCCCCCCCCCC(OC(C)C)=O
Chemical formula: C17H34O2
Molar mass: 270.457 g·mol−1
Density: 0.85 g/cm3
Boiling point: 167 °C (333 °F; 440 K) at 9 mmHg
CAS Number: 110-27-0
Chem/IUPAC Name: Tetradecanoic acid, isopropyl ester
EINECS/ELINCS No: 203-751-4
COSING REF No: 34699
Boiling Point: 192-193°C
Melting Point: 2-3°C
Solubility: Soluble in benzyl benzoate, ethyl lactate, paraffin oil

Insoluble in water
Molecular Weight: 270.5 g/mol
XLogP3-AA: 7.2
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 14
Exact Mass: 270.255880323 Da
Monoisotopic Mass: 270.255880323 Da
Topological Polar Surface Area: 26.3Ų
Heavy Atom Count: 19
Formal Charge: 0
Complexity: 199
Isotope Atom Count: 0

Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
CAS number: 110-27-0
EC number: 203-751-4
Hill Formula: C₁₇H₃₄O₂
Molar Mass: 270.45 g/mol
HS Code: 2915 90 33
Boiling point: 140 °C (3 hPa)

Density: 0.85 g/cm3 (20 °C)
Flash point: >150 °C
Ignition temperature: >300 °C
Vapor pressure: <1 hPa (20 °C)
Solubility: <0.05 mg/l
CBNumber: CB9482638
Molecular Formula: C17H34O2
Molecular Weight: 270.45
MDL Number: MFCD00008982
MOL File: 110-27-0.mol

FIRST AID MEASURES of ISOPROPYL MYRISTATE (IPM):
-Description of first-aid measures:
*If inhaled:
After inhalation: 
Fresh air.
*In case of skin contact: 
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact: 
Rinse out with plenty of water. 
Remove contact lenses.
*If swallowed:
After swallowing: 
Make victim drink water (two glasses at most). 
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed: 
No data available

ACCIDENTAL RELEASE MEASURES of ISOPROPYL MYRISTATE (IPM):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains. 
Collect, bind, and pump off spills. 
Observe possible material restrictions
Take up with liquid-absorbent material.
Dispose of properly. 
Clean up affected area.

FIRE FIGHTING MEASURES of ISOPROPYL MYRISTATE (IPM):
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2) 
Foam 
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Advice for firefighters:
In the event of fire, wear self-contained breathing apparatus
-Further information:
none

EXPOSURE CONTROLS/PERSONAL PROTECTION of ISOPROPYL MYRISTATE (IPM):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
Splash contact:
Material: Chloroprene
Minimum layer thickness: 0,65 mm
Break through time: 30 min
*Respiratory protection:
Not required.
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of ISOPROPYL MYRISTATE (IPM):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.

STABILITY and REACTIVITY of ISOPROPYL MYRISTATE (IPM):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Incompatible materials:
No data available


 

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