TOCOPHERYL ACETATE

TOCOPHERYL ACETATE = Vitamin E acetate = Alpha tocopheryl acetate (ATA) = Tocopherol Acetate

CAS Number: 7695-91-2
EC Number: 231-710-0
MDL number: MFCD00072042
Formula : C31H52O3

Tocopheryl acetate is the long, scientific name for vitamin E.
Tocopheryl acetate, also known as vitamin E acetate, is a common vitamin supplement with the molecular formula C31H52O3 (for 'α' form). 
Tocopheryl acetate is the ester of acetic acid and tocopherol (vitamin E). 
Tocopheryl acetate (TA) is a specific form of vitamin E that’s often found in skin care products and dietary supplements. 
D-alpha-tocopheryl acetate appears as odorless off-white crystals.
Also known as tocopheryl acetate, tocopherol acetate, or vitamin E acetate.
Vitamin E is known for Tocopheryl acetates antioxidant properties.

There is a slew of vitamin E molecule forms, either synthetically or naturally derived: d-alpha-tocopherol, d-alpha-tocopherol acetate, dl-alpha tocopherol, and dl-alpha tocopherol acetate. 
The "d" in front of the "alpha" denotes that the product is from natural sources, such as vegetable oils or wheat germ; the "dl" prefix indicates that the vitamin was created from a synthetic base. 
Antioxidants help to protect your body from damaging compounds called free radicals. 
D-alpha-Tocopherol acetate is a form of vitamin E used to treat and prevent vitamin deficiencies.
In nature, vitamin E comes in the form of tocopheryl or tocotrienol. 

Both tocopheryl and tocotrienol have four forms, known as alpha, beta, gamma, and delta. 
Alpha-tocopheryl (AT) is the most active form of vitamin E in humans.
ATA (Alpha Tocopheryl acetate) is more stable than AT, meaning ATA (Alpha Tocopheryl acetate) can better withstand environmental stresses such as heat, air, and light. 
This makes ATA (Alpha Tocopheryl acetate) ideal for use in supplements and fortified foods because ATA (Alpha Tocopheryl acetate) has a longer shelf life.
Alpha Tocopheryl acetate finds in a variety of skin care products. 

The antioxidant properties of vitamin E can help to prevent damage to skin caused by free radicals from UV exposure. 
Vitamin E may also have an anti-inflammatory effect on the skin.
Due to Alpha Tocopheryl acetates higher stability, Alpha Tocopheryl acetate is also used in vitamin E dietary supplements. Orally, Alpha Tocopheryl acetate is converted to Alpha-tocopheryl within the intestine. 
Vitamin E is in most multi-vitamins.
While tocopheryl acetate is more stable and has a longer shelf life, TOCOPHERYL ACETATE’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vitamin E. 

α-Tocopheryl acetate, also known as vitamin E acetate, is a synthetic form of vitamin E. 
α-Tocopheryl acetate is the ester of acetic acid and α-tocopherol.
Tocopheryl acetate is a specific type of vitamin E, in a class of organic chemical compounds known as tocopherols. 
These compounds are considered fat-soluble antioxidants, but are also said to have many other functions in the body. 
The antioxidants in vitamin E are known to protect the cell from damage that naturally occurs from free radicals. 
These free radicals are formed in the body during normal processes (such as energy production).
There are eight different types of natural vitamin E; alpha tocopherol is the most abundant type in human tissue. 
Alpha tocopherol is the only variation of vitamin E used to treat vitamin E deficiencies.

Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. 
In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the alpha-tocopherol stereoisomers. 
Moreover, RRR-alpha-tocopherol acetate is a relatively stabilized form of vitamin E that is most commonly used as a food additive when needed. 
Alpha-tocopherol acetate is subsequently most commonly indicated for dietary supplementation in individuals who may demonstrate a genuine deficiency in vitamin E. 

Vitamin E itself is naturally found in various foods, added to others, or used in commercially available products as a dietary supplement. 
Tocopheryl acetate is a fat-soluble vitamin from a class of organic compounds, many of which are known to have vitamin E activity.  
Vitamin E is an antioxidant - naturally occurring chemicals that help prevent cell damage by fighting off highly reactive free radicals.   
Antioxidants can be found a variety of places in nature: fruits, vegetables, marine plants, even some seafood. 
Tocopherol and tocopheryl acetate can be made naturally from vegetable oils or synthetically from petroleum products. 
The two have distinct names for supplement labeling; d-alpha tocopherol or tocopheryl acetate distinguishes a naturally derived supplement while dl-alpha tocopherol or tocopheryl acetate distinguishes a synthetic supplement. 

As a cosmetic ingredient the name tocopherol or tocopheryl acetate is simply applied so the source can not be determined from the label.  
A form of vitamin E, tocopheryl acetate is an ester of tocopherol. 
Tocopherol, or vitamin E, is found in many plants, dairy products, meat, eggs, cereals, and nuts.
E Vitamin E Acetate (dl-alpha-tocopheryl acetate) also has the lowest carbon footprint for Vitamin E in the personal care industry, assessed via Lifecycle analysis. 
Dl-a-Tocopheryl Acetate is a colorless to yellow or greenish yellow, practically odorless viscous oil. 
Dl-a-Tocopheryl Acetate is practically insoluble in water, and freely soluble in alcohol, chloroform, acetone, ether, and vegetable oils.
Tocopherol, or vitamin E, a fat-soluble vitamin is a naturally occuring antioxidant which can be isolated from vegetable oil. When isolated Tocopherol, is a viscous oil that varies in color from yellow to brownish red. 

Vitamin E actually refers to a group of eight nutrients that all have similar structures yet slightly different functions. The group consists of four tocopherols and four tocotrienols. 
Out of these eight nutrients, D-alpha-tocopherol is the most abundant and biologically active form in the human body. 
Vitamin E can be found naturally in avocado, pumpkin and wheat germ oil but is also synthetically derived. 
Tocopheryl acetate is the synthetically produced ester of tocopherol and acetic acid. 
In chemistry, an ester is a chemical compound derived from an acid, in this case, acetic acid, in which at least one hydroxyl group is replaced by an alkoxy group. 

Tocopheryl acetate is often used as an alternative to pure tocopherol because the phenolic hydroxyl group is blocked, providing a less acidic product with a longer shelf life.
Vitamin E can be found naturally in avocado, pumpkin, and wheat germ oil but is also synthetically derived.
DL-Alpha tocopheryl acetate, or Vitamin E Acetate, is the stable form of Vitamin E most often used in cosmetic formulations for Vitamin E Acetates skin care benefits. 
Tocopherols and tocotrienols can rapidly scavenge lipid peroxyl free radicals by acting as chain breaking antioxidants, thus preventing them from reacting with other lipids. 

This process is key to limiting the propagation of lipid peroxidation in membranes. 
DL-α-Tocopherol acetate is the ester form of α-Tocopherol. 
Tocopherols are a series of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring. 
Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. 
α-Tocopherol is the form of tocopherol preferentially absorbed by humans.
Vitamin E is a vitamin that dissolves in fat. 

Vitamin E is found in many foods including vegetable oils, cereals, meat, poultry, eggs, fruits, vegetables, and wheat germ oil.
Vitamin E is used in fortified foods and in food supplements.
The reference intake for vitamin E is 12mg (as d-alpha tocopherol equivalents)
The upper limit for vitamin E is 300mg (as d-alpha tocopherol equivalents)
Tocopheryl acetate may appear to be arcane nutritional chemistry, but tocopheryl acetate is key to understanding how the body absorbs natural and synthetic supplements differently. 

Tocopheryl acetate consists of tocopheryl (which is the vitamin E part) and acetic acid. 
Tocopheryl acetate’s actually the ester of acetic acid and tocopherol, a pure form of vitamin E.
Tocopheryl Acetate is the ester of Tocopherol. 
On a molecular level Tocopheryl acetate is an tocopherol molecule with an acetate group added.  
Tocopheryl acetate is fat-soluble. 

The term Vitamin E doesn’t just refer to one molecule but a family of molecules that are chemically similar. 
D-Alpha Tocopheryl Acetate, also known as Vitamin E Acetate, is the stereoisomer of alpha-tocopherol found in nature.
Dl alpha tocopherol is a synthetic form of vitamin E and is used for Dl alpha tocopherols antioxidant properties.
Tocopheryl acetate is a chemical compound consisting of acetic acid and tocopherol (vitamin E). 
In cosmetics, especially, Tocopheryl acetates stability compared to some other vitamin E sources is valued. 

Uses and Applications of TOCOPHERYL ACETATE:
-TOCOPHERYL ACETATE’s the most commonly used version of pure vitamin E in cosmetics. 
-Using Alpha-tocopheryl on the skin, especially with vitamin C, helps to prevent UV damage to the skin. 
-Using Alpha-tocopheryl with vitamin C on the skin decreased sunburned cells, DNA damage, and skin pigmentation following UV exposure. 
-While Alpha Tocopheryl acetate is less sensitive to heat and light than Alpha Tocopheryl is, there’s less conversion of Alpha Tocopheryl acetate to the active Alpha Tocopheryl form within the skin. 
This is because the cells in the upper layer of your skin are much less metabolically active. 
-α-Tocopheryl acetate is often used in dermatological products such as skin creams. 
-α-Tocopheryl acetate is not oxidized and can penetrate through the skin to the living cells, where about 5% is converted to free tocopherol. 
-α-Tocopheryl acetate is used as an alternative to tocopherol itself because the phenolic hydroxyl group is blocked, providing a less acidic product with a longer shelf life. 

-α-Tocopheryl acetate is slowly hydrolyzed after α-Tocopheryl acetate is absorbed into the skin, regenerating tocopherol and providing protection against the sun's ultraviolet rays. 
-Vitamin E (tocopheryl acetate) goes to work acting as an antioxidant to protect the cells and DNA, promoting cellular health. 
Because vitamin E is fat-soluble, this means that  vitamin E can stop the production of free radicals formed when the body breaks down fat for energy.
-Tocopheryl acetate is commonly used to formulate dietary supplements as well as skin care products.
-Treating vitamin E deficiency.
-Promoting healthy skin (such as moisturizing and preventing wrinkles).
-Helping with wound healing.

-Reducing inflammation.
-Slowing the progression of age-related macular degeneration (AMD).
-Treating heart disease.
-Improving cognitive decline, such as Alzheimer’s disease.
-Vitamin E is known to be a fat-soluble antioxidant that has the capability to neutralize endogenous free radicals
-Tocopherol Acetate is a derivative of Vitamin E. 
-Tocopherol Acetate acts in cosmetics as an antioxidant. 
-Tocopherol Acetate can be produced synthetically or of natural origin, extracted from soybean or sunflower oil for example. -Tocopherol Acetate is often used in cosmetics as an alternative to pure tocopherol, because Tocopherol Acetate is considered more stable and less acidic.

-Tocopherol Acetate is authorized organically, when Tocopherol Acetate is of plant origin.
-Antioxidant: Inhibits reactions favored by oxygen, thus preventing oxidation and rancidity
-Skin care agent: Keeps the skin in good condition
-Tocopheryl acetate is used as an alternative to free tocopherol because Tocopheryl acetate is more stable in the formulation.   
-The tocopheryl acetate serves as an antioxidant for the product and for Tocopheryl acetates skin conditioning properties.
-The Vitamin E acetate forms, d-α-Tocopheryl Acetate and dl-α-Tocopheryl Acetate, are extremely stable in formulations and therefore the compounds of choice for cosmetic preparations with maximum vitamin efficacy. 
-The tocopherol forms dl-α -Tocopherol and Mixed Tocopherols are mostly used to stabilize oxygen-sensitive ingredients in cosmetic formulations, to enhance the shelf-life of the formulation. 

-Tocopheryl acetate is a skin-conditioning agent and antioxidant.
-Tocopheryl acetate is found in thousands of personal care products, including lipstick, sunscreen, moisturizer, conditioner, shampoo, makeup, nail polish, lip balm, and other products.
-Vitamin E Acetate provides all of the benefits of Vitamin E with the added benefit of sustainability. 
-The most widely used active ingredient in the beauty industry, Vitamin E has proven antioxidant effects, enhances moisturization and strengthens the skin barrier. 
-Vitamin E helps to counteract the appearance of inflammation linked to oxidative processes through downregulation of Vitamin Es mediators.

-Pharmaceutical products:
Suitable for use in pharmaceutical applications.
-Dietary supplements:
Suitable for use in dietary supplements with a lipophilic base, e.g., ointments, creams, oils, soft gelatin capsules, as well as in aqueous preparations, e.g., syrups, drops, tonics, and solubilizates in conjunction with a solubilizing agent.
-Food products:
Suitable for the fortification of fats, e.g., in regular and low-fat margarine as well as in oils and fat-containing foods, such as cakes, biscuits, and dairy products.

-Esters of Tocopherol are often used in cosmetic and personal care products. 
These esters include, Tocopheryl Acetate, the acetic acid ester of Tocopherol; Tocopheryl Linoleate, the linoleic acid ester of Tocopherol; Tocopheryl Linoleate/Oleate, a mixture of linoleic and oleic acid esters of Tocopherol; Tocopheryl Nicotinate, the nicotinic acid ester of Tocopherol; and Tocopheryl Succinate, the succinic acid ester of Tocopherol. 
-Potassium Ascorbyl Tocopheryl Phosphate, a salt of both vitamin E (Tocopherol) and vitamin C (Ascorbic Acid) may also be used in cosmetic products.
-In cosmetics and personal care products, Tocopherol and other ingredients made from Tocopherol, including Tocopherol esters are used in the formulation of lipstick, eye shadow, blushers, face powders and foundations, moisturizers, skin care products, bath soaps and detergents, hair conditioners, and many other products.
-Vitamin E is the most widely used active ingredient in Personal Care. 

-Vitamin Es central role in Personal Care is that of a strong antioxidant, capturing free oxygen radicals generated by exposure to UV-light or pollution and preventing further damage. 
Generally, the addition of vitamin antioxidants (vitamin E and vitamin C) improves the photoprotection provided by sunscreens as a biological second line of defense against UV-induced premature skin ageing.
-In the form of Tocopheryl Acetate, vitamin E is extremely stable in formulations. 
Indeed, Tocopheryl Acetate is the vitamin compound of choice for cosmetic preparations to deliver maximum vitamin efficacy. In the form of Tocopherols, Tocopheryl Acetate is mostly used to stabilise oxygen sensitive ingredients in formulations.
-Vitamin E used for Vitamin Es powerful antioxidant, protective and natural skin conditioning properties. 
-Vitamin E is both a nutrient and an antioxidant.

-Vitamin E supports health benefit solutions in all stages of life and includes brain, eye and cardiovascular health, as well as supporting and nourishing beauty from within.
-To use vitamin E oil for facial concerns (like wrinkles, acne, etc.). 
-Vitamin E oil is suitable for all Human food , dietary supplement & cosmetic applications.
-The lipophilic or oil-based nature of tocopherol makes tocopherol a great ingredient for providing the skin with moisture protecting oil that allows for tocopherols benefits to be absorbed through the skin. 
However, in order for the body to absorb and use the tocopherol from tocopheryl acetate, tocopheryl acetate must remove the acetate group. 

-Vitamin E is used to help protect the skin’s natural barrier, help retain the skin’s moisture, heal and provide the skin with antioxidant properties.
-Vitamin E helps to maintain the skin’s natural barrier. 
The barrier consists of the uppermost layers of the skin and the oils, amino acids, ceramides and fatty acids. 
The barrier, as its name suggests protects the skin from allergens, bacteria and prevents transepidermal water loss or TEWL. TEWL occurs when water from the skin is lost to the environment, it is particularly common in dry environments or in aging skin. 
The lipophilic or oil loving nature of vitamin E helps to replenish the skin’s natural oils and aids in maintaining this natural barrier. 
-When tocopheryl acetate is delivered to your skin through the oil glands, tocopheryl acetate hydrates the uppermost layer of skin and improves water-binding capacity. 

Tocopheryl acetate is also considered an effective ingredient for imparting skin protection and supporting treatments for eczema. 
-Vitamin E, whether as tocopherol or tocopheryl acetate, is included in a wide variety of skin care products due to its powerful antioxidant activity.
-Vitamin E as an antioxidant may help to reduce the negative effects of free radicals on the skin. 
Researchers have determined that vitamin E is the major lipid soluble or oil-soluble antioxidant in skin.
-Vitamin E may have protective abilities against the harmful effects of UV rays. 
The mechanism of action is similar to that of vitamin C, acting as an antioxidant to reduce the effects of free radicals produced by exposure to the sun. 

This is why often find vitamin E in sunscreen formulations. 
-Vitamin E protects cell membranes from damage by oxygen free radicals.  
Vitamin E can prevent premature aging of the skin induced by UV irradiation and lipid peroxidation.
-Alpha Tocopherol is susceptible to UV irradiation, being rapidly converted to tocopheroxy radicals that use up other anitoxidants.  
Use of Vitamin E Acetate, an ester of alpha tocopherol helps overcome this limitation.  
Tocopheryl acetate is bioconverted to Tocopheryl acetates biologically active form, vitamin E, within the skin when applied topically.  
Topical use of tocopherol and alpha tocopheryl acetate are more effective than dietary supplementation in increasing the vitamin E content of the skin.

-Vitamin E is sometimes used for improving physical endurance, increasing energy, reducing muscle damage after exercise, and improving muscle strength.
-Some people apply vitamin E to their skin to keep it from aging, sunburn, scarring, lice, stretch marks, and to protect against the skin effects of chemicals used for cancer therapy (chemotherapy).
-Vitamin E is also used for cataracts, age-related vision loss (age-related macular degeneration), asthma, respiratory infections, skin disorders, aging skin, sunburns, cystic fibrosis, infertility, impotence, chronic fatigue syndrome (CFS), neurodegenerative disease called. 

-For fortification of margarine, oil and fat, nutrition products and baby food,also used in soft capsules.
-Tocopheryl acetate is a form of vitamin E, an antioxidant, which helps fight free radical damage and promote skin healing to diminish signs of aging. 
-Tocopheryl acetate also provides moisture and strengthens skin’s protective barrier to prevent moisture loss. 
-This form of vitamin E is often used in cosmetics because Tocopheryl acetate lasts longer and keeps oils and ingredients from going rancid.
-The esther of acetic acid and tocopherol; effective antioxidant and anti-inflammatory agent. 
Provides moisturization to help smooth & hydrate the skin.

-Tocopheryl acetate is used as an alternative to tocopherol itself because the phenolic hydroxyl group is blocked, providing a less acidic product with a longer shelf life.
The acetate is slowly hydrolyzed after Tocopheryl acetate is absorbed into the skin, regenerating tocopherol and providing protection against the sun's ultraviolet rays.
-Tocopheryl acetate is often used in dermatological products such as skin creams. 
-Tocopheryl acetate is not oxidized and can penetrate through the skin to the living cells, where about 5% is converted to free tocopherol. 
-Tocopherol (vitamin E) is an oil, the ester of which is usually used in makeup and skincare formulas. 
Tocopherol is combined with acetic acid, which is actually the main ingredient in vinegar. 

Together, Tocopherol and acetic acid make tocopheryl acetate, which is favored for use in products over regular vitamin E because tocopheryl acetate’s more stable and doesn’t go bad as quickly.
-Vitamin E acetate is used as a fortifying agent and dietary supplement in food. 
-Vitamin E acetate is used in dermatological products such as skin creams. 
-Vitamin E acetate is an alternative to tocopherol and provides protection against the sun’s ultraviolet rays.
-Tocopheryl acetate is a potent antioxidant that protects the skin by reducing the formation of free radicals from environmental aggressors. 

-Tocopheryl acetate also enhances the efficacy of active sunscreen ingredients. 
-Tocopheryl acetate is a natural skin-conditioner with hydrating properties, Tocopheryl acetate reduces inflammation, aids with wound healing and strengthens the skin barrier, helping to maintain the lipid balance and protect the skin from transepidermal water loss.
-Tocopheryl acetate is derived from edible vegetable oils by suitable physical and chemical means. 
-Tocopheryl acetate is intended for use as Vitamin E in dietary supplement and food industry. 

The esters of d-alpha tocopherol have reduced susceptibility to degradation when exposed to air or elevated processing temperatures; these particular benefits allow for flexibility in product formulations.
-Tocopheryl acetate is a form of vitamin E, a natural skin-conditioning agent and antioxidant. 
Tocopheryl acetate is the ester of acetic acid and tocopherol and is often used as an alternative to pure tocopherol (or undiluted vitamin E) because Tocopheryl acetate is considered more stable and less acidic.
-Dl alpha tocopherol is found in many personal care products such as skin creams and lotions to promote skin healing and reduce scarring after injuries such as burns. 

-Baby and Body Powder, Baby Wipes, Cold Sore Products, Cosmetics: Blush, Eye liner, Foundation, Mascara, Nail polish,Pressed powder
-Antifungal Products: Athlete’s foot, Jock itch
-Deodorants, Gum and Mints, Hair Care Products: Conditioner, Hair dye, Hairspray, Hot oil treatments, Leave-in conditioner, Mousse, Sculpting cream, Shampoo
-Lip Balms/Lipsticks, Lotions and Moisturizers, Shaving Creams and Gels, Skin Care Products: Antioxidant creams, Anti-itch creams/gels, Scar treatment

-Soaps and Cleansers: Bar soap, Body wash, Cleansing cloths
-Vitamin E in a wide range of cosmetic applications from an ingredient of quasi-drugs and other skin care products such as lotions, age-defying creams, sunscreens, and lipsticks.
-Tocopheryl acetate is a form of vitamin E, a natural skin-conditioning agent and antioxidant. 
-Tocopheryl acetate is a fat-soluble vitamin that can be isolated from vegetable oils. 
-Tocopheryl acetate is also found in dairy products, meat, eggs, cereals, nuts, and leafy green and yellow vegetables. 
-Attributed with antioxidant, anti-aging, moisturizing, anti-inflammatory, and enhanced SPF properties, tocopherol acetate is valued both as a dietary supplement and skincare active
-D-alpha Tocopherol Acetate is a naturally derived form of Vitamin E. 
D-alpha Tocopherol Acetate’s provides antioxidant protection and even shields skin from early stage UV damage.

Synonyms:
Alpha tocopheryl acetate (ATA)
Vitamin E acetate
Tocopherol acetate
A-tocopherol
Alpha tocopherol
D-alpha tocopherol
Vitamin E acetate
Alpha-Tocopherol acetate
D-alpha-tocopherol acetate
DL-alpha-Tocopheryl acetate
(2S,4'S,8'S)-5,7,8-Trimethyltocol acetate
D-ALPHA-TOCOPHEROLACETATE
dl-a-Tocopheryl Acetate
2H-1-Benzopyran-6-ol
Vitamin E alpha acetate
Dl alpha tocopherol

Physical and chemical properties of TOCOPHERYL ACETATE:
Molecular Weight: 472.74
Description: Light-yellow, viscous, virtually odorless oil.
Solubility: 
Soluble in hydrocarbons, alcohols, fats, and oils.
Insoluble in water.
Appearance Form: liquid
Odor: No data available
Odor Threshold: No data available
pH: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: 224 °C at 0,4 hPa
Flash point: No data available
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: No data available
Vapor density: No data available
Density: No data available
Relative density: 0,95 - 0,964 at 25 °C
Water solubility: 0,0008 g/l at 20 °C - OECD Test Guideline 105- slightly soluble
Partition coefficient n-octanol/water: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity:
Viscosity, kinematic: 5706 mm2/s at 20 °C - OECD Test
Viscosity, dynamic: 701 mPa.s at 40 °C
Explosive properties: No data available
Oxidizing properties: No data available

How Tocopheryl acetate Is Made?
Tocopheryl acetate is an ester of tocopherol, which is vitamin E. 
Tocopherol production can begin by drying out oil seeds to remove some of their moisture. 
After removing the shells or hulls, the seeds are usually ground, then mixed with hot water and boiled to allow some of the oil to float. 
The milled seed is then turned into a paste and kneaded or pressed to separate the oil. 
At that point, the oil can be refined to remove flavor or odor. 
Tocopherol can also come from animal tissues.

Exposure controls/personal protection of TOCOPHERYL ACETATE:
-Control parameters:
Ingredients with workplace control parameters.
-Exposure controls:
Personal protective equipment:
Eye/face protection:
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses.
Body Protection
Impervious clothing.
The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Skin protection:
Handle with gloves. 
Gloves must be inspected prior to use. 
Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. 
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. 
Wash and dry hands.
Respiratory protection:
Respiratory protection not required. 
For nuisance exposures use type OV/AG (US) or type ABEK (EU EN 14387) respirator cartridges. 
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure: No special environmental precautions required.

First aid measures of TOCOPHERYL ACETATE:
-Description of first-aid measures:
If inhaled:
After inhalation: 
Move person to fresh air. 
If not breathing, give artificial respiration. 
If breathing is difficult, give oxygen. 
Obtain medical aid.
Fresh air.
In case of skin contact: 
Take off immediately all contaminated clothing.  
Rinse skin with water/ shower.
In case of eye contact:
After eye contact: 
Rinse out with plenty of water. 
Remove contact lenses.
If swallowed
After swallowing: 
Make victim drink water (two glasses at most). 
Consult doctor if feeling unwell.

Accidental release measures of TOCOPHERYL ACETATE:
-Personal precautions, protective equipment and emergency procedures:
Advice for non-emergency personnel: 
Evacuate the danger area, observe emergency procedures, consult an expert.
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains. 
Collect, bind, and pump off spills. 
Observe possible material restrictions. 
Take up with liquid-absorbent material.
Dispose of properly. 
Clean up affected area.

Handling and storage of TOCOPHERYL ACETATE:
-Precautions for safe handling:
Avoid contact with skin, eyes, and personal clothing. 
Wash hands thoroughly after handling. 
Avoid breathing fumes. 
Use only with adequate ventilation. 
Wear suitable protective clothing, gloves, and eye/face protection. 
Minimize dust generation and accumulation. 
Keep container tightly closed. 
Open and handle container with care. 
Do not eat, drink, or smoke while handling.
-Conditions for safe storage, including any incompatibilities:
Storage conditions:
Store in a tightly-closed container when not in use. 
Store in a cool, dry, well-ventilated area away from incompatible substances.
Store long-term at 2-8°C.
Storage stability:
Recommended storage temperature: 2 - 8 °C
Store under inert gas. 

Firefighting measures of TOCOPHERYL ACETATE:
-Extinguishing media:
Suitable extinguishing media:
Carbon dioxide (CO2) 
Foam Dry powder
Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Special hazards arising from the substance or mixture:
Carbon oxides
-Advice for firefighters:
In the event of fire, wear self-contained breathing apparatus.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

Stability and reactivity of TOCOPHERYL ACETATE:
Stability:
In contrast to vitamin E-alcohol, vitamin E-acetate is resistant to heat and oxygen. 
Stored in its unopened original packaging at room temperature (max. 25 °C), the product is stable for at least 36 months.
Reactivity: No data available
Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
Possibility of hazardous reactions:
Violent reactions possible with: Strong oxidizing agents
Conditions to avoid: no information available