PRODUCTS

VERATRALDEHYDE

CAS NUMBER: 120-14-9

EC NUMBER: 204-373-2

MOLECULAR FORMULA: C9H10O3

MOLECULAR WEIGHT: 166.17

Veratraldehyde is a flavoring compound.
Veratraldehyde is an organic compound widely used as an odorant.
Veratraldehyde The Compound is structurally related to benzaldehyde.

Veratraldehyde is popular commercially because of its pleasant woody scent.
Veratraldehyde is a derivative of vanillin from which it is prepared by methylation.
Veratraldehyde can be used as an intermediate in the synthesis of some pharmaceutical drugs.

Veratraldehyde (3,4-dimethoxybenzaldehyde) is an organic compound that is widely used as a flavorant and odorant.
The compound is structurally related to benzaldehyde.
This compound is popular commercially because of its pleasant woody fragrance.
Veratraldehyde is derivative of vanillin, from which it is prepared by methylation.
Veratraldehyde can be used as an intermediate in the synthesis of some pharmaceutical drugs including amiquinsin

-hoquizil
-piquizil
-prazosin
-quinazoline
-tiapamil
-toborinone
-verazide
-vetrabutine.

Veratraldehyde appears as needles or chunky light peach powder.
Veratraldehyde has an odor of vanilla beans.
Veratraldehyde is a dimethoxybenzene that is benzaldehyde substituted by methoxy groups at positions 3 and 4.
Veratraldehyde is found in peppermint, ginger, raspberry, and other fruits.
Veratraldehyde has a role as an antifungal agent.
Veratraldehyde is a member of benzaldehydes and a dimethoxybenzene.

Veratraldehyde is a dimethoxybenzene, benzaldehyde substituted with methoxy groups at positions 3 and 4.
Veratraldehyde is found in mint, ginger, raspberry and other fruits.
Veratraldehyde has a role as an Antifungal agent.

Veratraldehyde is a member of benzaldehydes and dimethoxybenzene.
Veratraldehyde looks like a needle or light peach powder.
Veratraldehyde has a vanilla bean-like odor.

Veratraldehyde is a substance incompatible with strong oxidizing agents.
Veratraldehyde is not compatible with strong bases.
VERATRALDHYDE is an aldehyde.

Reactivity Profile:
VERATRALDEHYDE is incompatible with strong oxidizing agents and strong bases.
VERATRALDEHYDE is an aldehyde. Aldehydes are readily oxidized to give carboxylic acids.
These autoxidation reactions are activated by light, catalyzed by salts of transition metals, and are autocatalytic (catalyzed by the products of the reaction).

A pure grade Veratraldehyde is excellent perfume material with more warmth than vanillin and produce excellent effect in oriental type of fragrances, woody musk bases.
Veratraldehyde is also used as variation for or in company with anisaldehyde.
In flavour compositions, it is mainly used in imitation vanilla, nut and butterscotch.
Veratraldehyde is also used in various fruit complexes.
The concentration used is normally 10 to 30 ppm in finished products.

-Formula: C9H10O3
-Net Charge: 0
-Average Mass: 166.17390
-Monoisotopic Mass: 166.06299
-refractive index: 1.5260 (estimate)
-FEMA: 3109 | VERATRALDEHYDE
-Flash point:>230 °F
-storage temp.: 2-8°C
-solubility alcohol: freely soluble
-form: Lumps or Fused Solid
-color: White to yellow
-Water Solubility: <0.1 g/100 mL at 22 ºC
-Sensitive: Air Sensitive
-JECFA: Number877
-Merck: 14,9951
-BRN: 473899
-Stability:Stable. Incompatible with strong bases, strong oxidizing agents.

Veratraldehyde being an aldehyde type, is easily oxidized to give carboxylic acids.
Combustible gases are produced by the combination of Veratraldehyde with azo, diazo compounds, dithiocarbamates, nitrides and strong reducing agents.
Veratraldehyde can react with air to give first peroxo acids and eventually carboxylic acids.

Veratraldehyde's autoxidation reactions are activated by light.
Veratraldehyde's autoxidation reactions are catalyzed by salts of transition metals.
Veratraldehyde's autoxidation reactions are autocatalytic, that is, they are catalyzed by the reaction products.
Veratraldehyde is a crystalline compound usually made by methylation of vanillin.

Veratraldehyde has an isomeric structure.
Veratraldehyde is a dimethoxybenzene, benzaldehyde substituted at positions 3 and 4 with methoxy groups.
Veratraldehyde is a compound found in some fruits.
Veratraldehyde is an antimicrobial agent that destroys fungi by suppressing their growth or reproductive ability.

Veratraldehyde is an excellent perfume material with more warmth than vanillin.
Veratraldehyde produces an excellent effect in oriental scents, woody musk bases.
Veratraldehyde is also used as a variation for or with anisaldehyde.
Veratraldehyde is mainly used in imitation vanilla, hazelnut and butterscotch in flavor compositions.

Chemical Properties:
White to brown or blue-gray needle crystal (crystallization in ether);
Sweet woody fragrance, fragrant grass aroma and strong flavor of vanilla blue;
Oxidized into odorless 3,4-dimethoxybenzoic acid (veratric acid) in the air;
Melting point 43~45℃;
Insoluble in cold water;
Soluble in hot water, ethanol and oil.
Natural products exist in the Java citronella oil and Hu Xanthium parsley oil and so on.
Use GB 2760 a 1996 provisions for the use of food spices.

Application:
This product is the intermediate of organic synthesis.
In pharmaceutical industry, it is used to synthesize methamphetamine and also used in the production of veterinary drug sulfonamide synergist.
Adding 0.02% (weight) of this veterinary drug into feed can increase the efficiency of the iodine drug synergistic added in feed, which can prevent and control the poultry bacterial infection.
Used as pharmaceutical intermediate and mainly used for antibiotic drug synthesis.

Preparation:
Veratraldehyde can be derived from the reaction of 3-methoxy-4-hydroxybenzaldehyde (vanillin) and dimethyl sulfate, or derived from the methylation of dimethyl sulfate with vanillin in alkaline conditions.

Veratraldehyde is a crystalline solid (mp 44.5–45°C) with a woody, vanillalike odor.
Veratraldehyde can be prepared by methylation of vanillin.
Veratraldehyde is used in oriental and warm, woody fragrances, as well as in flavor compositions for vanilla notes.
Veratraldehyde is an intermediate in, for example, the synthesis of pharmaceuticals.
Veratraldehyde has a very sweet, woody, vanilla-like odor with a warm, sweet, vanilla-like taste.
This compound gets oxidized in air to odorless veratric acid.

Veratraldehyde is also found in various fruit complexes.
Veratraldehyde is similar to white to brown or blue-gray crystals.
Veratraldehyde crystallizes in ether.
Veratraldehyde has a sweet woody scent.

Veratraldehyde is a compound with fragrant grass flavor and strong aroma of vanilla blue.
Veratraldehyde oxidizes in air to odorless 3,4-dimethoxybenzoic acid
Veratraldehyde is insoluble in water.
However, Veratraldehyde is soluble in hot water, ethanol and oil.

Veratraldehyde occurs naturally in Java citronella oil and parsley oil.
Veratraldehyde can be used in food seasonings under certain conditions.
Veratraldehyde is used in the pharmaceutical industry to synthesize methamphetamine
Veratraldehyde is also used in the manufacture of the veterinary drug sulfonamide synergist.

Veratraldehyde can prevent poultry bacterial infection and can control.
Veratraldehyde is a substance used as a pharmaceutical intermediate.
Veratraldehyde is used for antibiotic drug synthesis

Occurrence:
Reported among the constituents of the essential oils of Cymbopogon javanensis and Eryngium poterium.
Also reported found in raspberry, ginger, peppermint oil, Bourbon vanilla and mastic gum oil.

Preparation:
Prepared from vanillin by methylation of vanillin with dimethylsulfate under mildly alkaline conditions.
Aroma characteristics at 1.0%: phenolic, sweet vanilla, powdery, slightly woody with a candy and cocoa creaminess.
Taste characteristics at 50 ppm: phenolic, vanilla, sweet powdery cocoa, creamy, cherry-like with phenolic and balsamic nuances.

Veratraldehyde was used in the preparation of 4-chloromethyl-2-(dimethoxyphenyl)-1,3-dioxolane.
Veratraldehyde was used in the synthesis of (+)-lithospermic acid, having anti-HIV activity.
Veratraldehyde forms 1:1 inclusion complexes with cyclodextrins.
Veratraldehyde reacts with 3-acetyl-2,5-dimethythiophene to yield chalcone dye, (2E)-3-(3,4-Dimethoxyphenyl)-1-(2,5-dimethylthiophen-3-yl)prop-2-en-1-one.

Veratraldehyde (3,4-dimethoxybenzaldehyde, VD, VAD, VAld, Verapamil Related Compound E, Methylvanillin), a derivative of vanillin, is the chemical that is found and isolated from peppermint, ginger, bourbon vanilla, and fruits such as raspberry.
Veratraldehyde is widely used as a flavorant and odorant because of its pleasant woody fragrance.
Veratraldehyde also acts as a redox cycle agent.

Veratraldehyde can be derived from the reaction of dimethyl sulfate
Veratraldehyde can be derived from the methylation of alkali dimethyl sulfate with vanillin.
Veratraldehyde has the formula of an off-white crystalline solid.

USES OF VERATRALDEHYDE:

Veratraldehyde is used as a flavoring compound.
Veratraldehyde is widely used as an odorant.
Veratraldehyde is used in organic studies because it is related to benzaldehyde.

Veratraldehyde is widely used commercially because of its pleasant woody scent.
Veratraldehyde is also used by preparation by methylation.
Veratraldehyde can be used as an intermediate in the synthesis of some pharmaceutical drugs.

Veratraldehyde is used by extracting from mint, ginger, raspberry and other fruits.
Veratraldehyde is used in antifungal products as an Antifungal agent.

GENERAL PROPERTIES:
Appearance:Off-White Crystalline Solid
Boiling Point: 281°C
CAS Number: 120-14-9
ChEBI: 17098
Density: 1.114 g/cm3
HS Code: 29124900
IUPAC Name: 3,4-Dimethoxybenzaldehyde
InChI: 1S/C9H10O3/c1-11-8-4-3-7(6-10)5-9(8)12-2/h3-6H,1-2H3
InChIKeyi: WJUFSDZVCOTFON-UHFFFAOYSA-N
Melting Point: 40-43°C
Molar Mass: 166.17 g/mol
Molecular Formula: C9H10O3
NFPA 704: H-2,F-1,R-0,C-NA
RTECS Number: YX5088000
Refractive: 1.534 n/20D
Solubility: 1 mg/ml

Veratraldehyde is used in the production of carboxylic acid by oxidation.
Veratraldehyde is used naturally because it is a compound found in some fruits.
Veratraldehyde is used to suppress the growth or reproductive abilities of fungi.

Veratraldehyde is used as an antimicrobial agent that destroys some fungi.
Veratraldehyde is used as an excellent perfume material with a higher temperature than vanillin.
Veratraldehyde is used in oriental fragrances, woody musk bases.

Veratraldehyde is also used as a variation for or with anisaldehyde.
Veratraldehyde is mainly used as a vanilla-like flavor in flavor compositions.
Veratraldehyde is widely used as it is also found in various fruit complexes.

Veratraldehyde is also used in various fruit complexes.
The concentration used is normally 10 to 30 ppm in finished products.
Veratraldehyde is an organic compound that is widely used as a flavorant and odorant.
The compound is structurally related to benzaldehyde.
This compound is popular commercially because of its pleasant woody fragrance.
Veratraldehyde is derivative of vanillin, from which it is prepared by methylation.

Veratraldehyde is also used in its crystallized form in ether.
Veratraldehyde is used to mask odor in some sprays because it has a sweet woody scent.
Veratraldehyde is used in most industries as a compound with fragrant grass flavor and strong vanilla blue flavor.

VERATRALDEHYDE is used by extracting from Java citronella oil and parsley oil.
Veratraldehyde can be used in food seasonings under certain conditions.
Veratraldehyde is used in the pharmaceutical industry to synthesize methamphetamine.

Veratraldehyde is also used in the manufacture of the veterinary drug sulfonamide synergist.
Veratraldehyde can be used to prevent poultry bacterial infection.
Veratraldehyde is used as pharmaceutical intermediate
Veratraldehyde is used for antibiotic drug synthesis.

APPLICATIONS OF VERATRALDEHYDE:

-Organic chemistry syntheses

-Cosmetic

-Agriculture

-Food Industry

-Odor masking products

-Spray manufacture

-Deodorant production

-Perfumery

-Aroma Industry

-Medical Pharmaceuticals

-Pharmacological products

-Medicine

The invention discloses a preparation process of vertraldethyde;
Veratraldehyde is used as a main synthetic raw material and a solvent;
A formylation reaction is performed by veratrole and a complex generated by N-methylformanilide and phosphorus oxychloride; a product is obtained after hydrolyzation;
The using amount of the solvent during the reaction is reduced, and the yield of a single batch is increased.
Meanwhile, a lot of veratrole and N-methylaniline can be recovered for recycle, which reduces the production cost to a large extent.
In addition, the charging temperature is increased, and thus complexation and the formylation reaction can be performed simultaneously, which saves a lot of time; and the product after distillation has purity of up to above 99%

PHYSICAL PROPERTIES OF VERATRALDEHYDE:

Molecular Weight: 166.17

Exact Mass: 166.062994177

Monoisotopic Mass: 166.062994177

Form: Solid

Color: White

Boiling Point: 281.0 °C

Melting Point: 43.0 °C

Flash Point: greater than 230 °C

Solubility: 6.32 mg/mL at

CHEMICAL PROPERTIES OF VERATRALDEHYDE:

Covalently-Bonded Unit Count: 1

Compound Is Canonicalized: Yes

XLogP3: 1.5

Hydrogen Bond Donor Count: 0

Hydrogen Bond Acceptor Count: 3

Rotatable Bond Count: 3

Topological Polar Surface Area: 35.5 Å²

Heavy Atom Count: 12

Formal Charge: 0

Complexity: 147

LogP: 1.22

STORAGE OF VERATRALDEHYDE:

Veratraldehyde should be kept away from sources of ignition.
Veratraldehyde should be stored away from light.
Veratraldehyde should be stored in the refrigerator.

Veratraldehyde should be stored separately from strong oxidizing agents.
Veratraldehyde should be kept separate from strong bases.
Veratraldehyde should be stored separately from strong reducing agents.

Veratraldehyde is an organic compound that is widely used as a flavorant and odorant.
The compound is structurally related to benzaldehyde.
This compound is popular commercially because of its pleasant woody fragrance.
Veratraldehyde is derivative of vanillin, from which it is prepared by methylation.
Veratraldehyde was used in the preparation of 4-chloromethyl-2-(dimethoxyphenyl)-1,3-dioxolane.
Veratraldehyde was used in the synthesis of (+)-lithospermic acid, having anti-HIV activity.
Veratraldehyde forms 1:1 inclusion complexes with cyclodextrins.
Veratraldehyde reacts with 3-acetyl-2,5-dimethythiophene to yield chalcone dye, (2E)-3-(3,4-Dimethoxyphenyl)-1-(2,5-dimethylthiophen-3-yl)prop-2-en-1-one.

Since Veratraldehyde reacts with air, it should be stored in a closed environment without air.
Veratraldehyde should be stored at temperatures lower than room temperature.
Veratraldehyde should be stored in damp places.

Veratraldehyde should be stored in a cool environment.
Veratraldehyde should be kept in dry containers.

Veratraldehyde should be stored at low temperatures.
Veratraldehyde should be stored away from high reagents.
Veratraldehyde should preferably be stored in glass bottles.

SYNONYMS:

Veratric aldehyde
Benzaldehyde, 3,4-dimethoxy-
Methylvanillin
Vanillin methyl ether
Veratral
Veratryl aldehyde
Veratrum aldehyde
3,4-Dimethoxy benzaldehyde
p-Veratric aldehyde
4-O-Methylvanillin
3,4-Dimethoxybenzenecarbonal
Protocatechualdehyde dimethyl ether
Protocatechuic aldehyde dimethyl ether
Protocatechuecaldehyde dimethyl ether
Benzaldehyde,4-dimethoxy-
Methyl vanillin
Veratrumaldehyde
4,3-dimethoxybenzaldehyde
4,5-dimethoxybenzaldehyde
3,4-Dimethoxybenzaldehyde
Benzaldehyde, 3,4-dimethoxy-Veratraldehyde
Veratraldehyde (3,4-Dimethoxybenzaldehyde)
3,4-Dimethoxybenzaldehyde