PRODUCTS

MERCAPTOACETIC ACID

Mercaptoacetic Acid is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Mercaptoacetic Acid is used in the following products: cosmetics and personal care products.
Mercaptoacetic Acid is used in the following products: laboratory chemicals and cosmetics and personal care products.

CAS Number: 68-11-1
EC Number: 200-677-4
MDL Number: MFCD00004876
Linear Formula: HSCH2COOH
Molecular Formula: C2H4O2S

SYNONYMS:
Acetyl mercaptan, Mercaptoacetate, Mercaptoacetic acid, 2-Mercaptoacetic acid, 2-Thioglycolic acid, Thiovanic acid, α-Mercaptoacetic acid, Glycolic acid, 2-thio-, Mercaptoacetic acid, Thioglycolic acid, Thiovanic acid, 2-Mercaptoacetic acid, 2-Thioglycolic acid, Thioglycollic acid, Acide thioglycolique, Glycolic acid, thio-, USAF CB-35, Kyselina merkaptooctova, Kyselina thioglykolova, UN 1940, Acetic acid, 2-mercapto-, NSC 1894, 2-Mercaptoacetic acid, 2-Thioglycolic acid, Acetic acid, mercapto-, Acide thioglycolique [French], Glycolic acid, 2-thio-, Glycolic acid, thio-, Kyselina merkaptooctova [Czech], Kyselina thioglykolova [Czech], Mercaptoacetic acid, Mercaptoessigsaeure, Thioglycolate, Thioglycolic acid, Thioglycollic acid, Thiovanic acid, [ChemIDplus] UN1940, 2-Mercaptoacetic Acid, 2-Mercaptoethanoic Acid, 2-Thioglycolic Acid, Glycolic Acid, 2-thio-, Mercaptoacetic Acid, Sulfhydrylacetic Acid, Thiovanic Acid, α-Mercaptoacetic Acid, Sulfanylacetic acid, 2-Sulfanylacetic acid, 2-Mercaptoacetic acid, Acetyl mercaptan, Mercaptoacetate, Mercaptoacetic acid, Thioglycolic acid, Thiovanic acid, mercaptoacetic acid, thioglycolic acid, 68-11-1, Acetic acid, mercapto-, 2-Mercaptoacetic acid, 2-Thioglycolic acid, Sulfanylacetic acid, Thioglycollic acid, 2-sulfanylacetic acid, Thiovanic acid, Mercaptoessigsaeure, Glycolic acid, thio-, Acide thioglycolique, Glycolic acid, 2-thio-, USAF CB-35, Acetic acid, 2-mercapto-, mercapto acetic acid, mercapto-acetic acid, Mercaptoethanoic acid, Kyselina thioglykolova, Kyselina merkaptooctova, Thioglykolsaeure, alpha-Mercaptoacetic acid, Merkaptoessigsaeure, NSC 1894, .alpha.-Mercaptoacetic acid, NSC-1894, MFCD00004876, Thioglycolic Acid (~90%), CHEMBL116455, DTXSID8026141, CHEBI:30065, 7857H94KHM, thioglycolicacid, DTXCID406141, CAS-68-11-1, Acide thioglycolique [French], Kyselina thioglykolova [Czech], CCRIS 4873, Kyselina merkaptooctova [Czech], HSDB 2702, EINECS 200-677-4, UN1940, BRN 0506166, UNII-7857H94KHM, AI3-24151, mercaptoactic acid, 2-mercaptoaceticacid, Sulfanylacetic acid #, mercaptoacetic acid (thioglycolic acid), HSCH2COOH, HSCH2CO2H, WLN: SH1VQ, EC 200-677-4, Thioglycolic acid, >=97%, Thioglycolic acid, >=98%, Thioglycolic acid, >=99%, 4-03-00-00600 (Beilstein Handbook Reference), THIOGLYCOLIC ACID [MI], Thioglycolic acid, LR, ~80%, CWERGRDVMFNCDR-UHFFFAOYSA-, NSC1894, MERCAPTOACETIC ACID [HSDB], THIOGLYCOLIC ACID [WHO-DD], THIOGLYCOLLIC ACID [MART.], STR00166, Tox21_201717, Tox21_303306, BDBM50336509, STL264219, AKOS000118940, DB15429, Thioglycolic acid, for synthesis, 97%, UN 1940, NCGC00249103-01, NCGC00257153-01, NCGC00259266-01, NCI60_001579, 1ST000892, DB-002789, Thioglycolic acid [UN1940] [Corrosive], M0052, NS00003173, EN300-19250, C02086, E78850, Q414738, InChI=1/C2H4O2S/c3-2(4)1-5/h5H,1H2,(H,3,4), Thiovanic acid, sulfanylacetate, Thioglycolic acid, 2-mercaptoacetate, 2-thioglycolicacid, Thioglycollic acid, 2-thio-glycolicaci, Thioglypollic Acid, Mercaptoacetic acid, 2-Thioglycolic acid, acidethioglycolique, Acide thioglycolique, Aceticacid,mercapto-, 2-MERCAPTOACETIC ACID, Thioglycolic acid solution, thioglycolic acid free acid, 2-Mercaptoacetic acid, 2-Thioglycolic acid, alpha-Mercaptoacetic acid, Mercaptoacetic acid, Mercaptoessigsaeure,Mercaptoethanoic acid, Merkaptoessigsaeure, SULFanylacetIC ACID, Thioglykolsaeure, Thioglycolic acid, 2-Mercaptoacetate, 2-Thioglycolate, a-Mercaptoacetate, a-Mercaptoacetic acid, alpha-Mercaptoacetate, Α-mercaptoacetate, Α-mercaptoacetic acid, Mercaptoacetate, Mercaptoethanoate, Sulfanylacetate, Sulphanylacetate, Sulphanylacetic acid, 2-Mercaptoacetate, bismuth (3+), sodium salt (3:1:3), 2-Mercaptoacetate, monoammonium salt, 2-Mercaptoacetate, monopotassium salt, Sodium thioglycolate, 2-Mercaptoacetate, calcium salt (1:1), Ammonium thioglycolate, 2-Mercaptoacetate, calcium salt (2:1), 2-Mercaptoacetate, calcium salt (2:1) salt, trihydrate, Calcium thioglycolate, Sodium thioglycollate, 2-Mercaptoacetate, monosodium salt, 2-Mercaptoacetate, Acetic acid, mercapto-, Thioglycolic acid, 2-Mercaptoacetic acid, 2-Thioglycolic acid, Acetic acid, mercapto-, Acide thioglycolique, Glycolic acid, 2-thio-, Glycolic acid, thio-, Kyselina merkaptooctova, Mercaptoessigsaeure, Thioglycolate, Thioglycollic acid, Thiovanic acid, Acetyl mercaptan, Mercaptoacetate, Mercaptoacetic acid, 2-Mercaptoacetic acid, 2-Thioglycolic acid, mercaptoacetic acid, thioglycolic acid, 68-11-1, 2-Mercaptoacetic acid, 2-Thioglycolic acid, Acetic acid, mercapto-, Sulfanylacetic acid, Thioglycollic acid, 2-sulfanylacetic acid, Thiovanic acid, Mercaptoessigsaeure, Glycolic acid, thio-, Acide thioglycolique, Glycolic acid, 2-thio-, thioglycolicacid, USAF CB-35, 2-Mercaptoacetate, Acetic acid, 2-mercapto-, mercapto acetic acid, mercapto-acetic acid, Mercaptoethanoic acid, alpha-Mercaptoacetic acid, Merkaptoessigsaeure, NSC 1894, .alpha.-Mercaptoacetic acid, NSC-1894, CHEMBL116455, DTXSID8026141, CHEBI:30065, 7857H94KHM, MFCD00004876, DTXCID406141, CAS-68-11-1, HSDB 2702, EINECS 200-677-4, UN1940, BRN 0506166, UNII-7857H94KHM, AI3-24151, mercaptoactic acid, 2-mercaptoaceticacid, Sulfanylacetic acid #, mercaptoacetic acid (thioglycolic acid), HSCH2COOH, HSCH2CO2H, WLN: SH1VQ, EC 200-677-4, Thioglycolic acid, >=97%, Thioglycolic acid, >=98%, Thioglycolic acid, >=99%, Thioglycolic Acid (~90%), 4-03-00-00600 (Beilstein Handbook Reference), THIOGLYCOLIC ACID [MI], THIOGLYCOLIC ACID [INCI], Thioglycolic acid, LR, ~80%, CWERGRDVMFNCDR-UHFFFAOYSA-, NSC1894, MERCAPTOACETIC ACID [HSDB], THIOGLYCOLIC ACID [WHO-DD], THIOGLYCOLLIC ACID [MART.], STR00166, Tox21_201717, Tox21_303306, BDBM50336509, AKOS000118940, DB15429, Thioglycolic acid, for synthesis, 97%, UN 1940, NCGC00249103-01, NCGC00257153-01, NCGC00259266-01, NCI60_001579, Thioglycolic acid [UN1940], FT-0628213, FT-0651867, M0052, NS00003173, EN300-19250, C02086, E78850, Q414738, InChI=1/C2H4O2S/c3-2(4)1-5/h5H,1H2,(H,3,4), Sulfanylacetic acid, 2-Sulfanylacetic acid, 2-Mercaptoacetic acid, Acetyl mercaptan, Mercaptoacetate, Mercaptoacetic acid, Thioglycolic acid, Thiovanic acid, mercaptoacetic acid, thioglycolic acid, 2-thioglycolic acid, acetic acid, mercapto, 2-mercaptoacetic acid, sulfanylacetic acid, thiovanic acid, mercaptoessigsaeure, thioglycollic acid, glycolic acid, thio, THIOGLYCOLIC ACID, TGA, 2-MERCAPTOACETIC ACID, MEQUINDOX, thioglycolic, Thioglycolate, THIOGLYCOLLIC ACID, Mercaptoacetate, 2-mercaptoacetate, mercaptoacetic, Acetic acid, 2-mercapto-, Acetic acid, mercapto-, 2-Mercaptoacetic acid, Glycolic acid, 2-thio-, Thiovanic acid, 2-Thioglycolic acid, Thioglycolic acid, α-Mercaptoacetic acid, Mercaptoacetic acid, 2-Mercaptoethanoic acid, Sulfhydrylacetic acid, NSC 1894, TGA, 2-Sulfanylacetic acid, 7283-42-3, 57755-20-1, Mercaptoacetic acid, Thiovanic acid, Thioglycollic acid, Acetomercaptan, Mercaptoacetate, 2-Mercaptoacetic acid, 2-Thioglycolic acid, Thioglycolic Acid, CAS 68-11-1, Molecular Formula HSCH2COOH,

Mercaptoacetic Acid is the organic compound HSCH2CO2H.
Mercaptoacetic Acid is often called mercaptoacetic acid (MAA).
Mercaptoacetic Acid contains both a thiol (mercaptan) and carboxylic acid functional groups.

Mercaptoacetic Acid is a colorless liquid with a strongly unpleasant odor.
Mercaptoacetic Acid is miscible with polar organic solvents.
Mercaptoacetic Acid appears as a colorless liquid with an unpleasant odor.

Density of Mercaptoacetic Acid is 1.325 g / cm3.
Mercaptoacetic Acid is used to make permanent wave solutions and depilatories.
Mercaptoacetic Acid is a sulfur-containing carboxylic acid.

Mercaptoacetic Acid is a conjugate acid of a thioglycolate(1-).
Mercaptoacetic Acid is under investigation in clinical trial NCT03238105 (Treatment of Periorbicular Hyperchromia Comparing 10% Mercaptoacetic Acid Peeling Versus Pulsed Intense Light).

Mercaptoacetic Acid is a colorless liquid with a strong, disagreeable odor characteristic of mercaptans
Mercaptoacetic Acid is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.

Mercaptoacetic Acid is a colorless liquid with a strong, disagreeable odor characteristic of mercaptans.
Mercaptoacetic Acid has been identified in human blood as reported by (PMID: 31557052 ).
Mercaptoacetic acid is not a naturally occurring metabolite and is only found in those individuals exposed to this compound or its derivatives.

Technically mercaptoacetic acid is part of the human exposome.
The exposome can be defined as the collection of all the exposures of an individual in a lifetime and how those exposures relate to health.
An individual's exposure begins before birth and includes insults from environmental and occupational sources.

USES and APPLICATIONS of MERCAPTOACETIC ACID:
Mercaptoacetic Acid is used as a chemical depilatory and is still used as such, especially in salt forms, including calcium thioglycolate and sodium thioglycolate.
Mercaptoacetic Acid is the precursor to ammonium thioglycolate, which is used for permanents.

Mercaptoacetic Acid and its derivatives break the disulfide bonds in the cortex of hair.
One reforms these broken bonds in giving hair a "perm".
Alternatively and more commonly, the process leads to depilation, as is done commonly in leather processing.

Mercaptoacetic Acid is also used as an acidity indicator, manufacturing of thioglycolates, and in bacteriology for preparation of thioglycolate media.
Thioglycolysis reactions are used on condensed tannins to study their structure.
Mercaptoacetic Acid has also been used to soften nails, either to reshape pincer nails into the correct position or to help topical antifungals penetrate the nail.

Organotin derivatives of Mercaptoacetic Acid isooctyl esters are widely used as stabilizers for PVC.
These species have the formula R2Sn(SCH2CO2C8H17)2.
Sodium thioglycolate is a component of thioglycolate broth, a special bacterial growth media.

It is also used in so-called "fallout remover" or "wheel cleaner" to remove iron oxide residue from wheels.
Ferrous iron combines with thioglycolate to form red-violet ferric thioglycolate.
Fine chemicals: Mercaptoacetic Acid is used as reagent for the preparation of different chemicals such as pesticides, herbicide, or for some polythiols and thio-esters.

Cleaning formulations uses of Mercaptoacetic Acid: Due to their ability to complex with metals, Mercaptoacetic Acid and Mercaptoacetic Acid salts are excellent additives in cleaning solutions, in particular for automotive applications including automotive wheel rim cleaners.
Mercaptoacetic Acid is also an additive for coating formulations for metal surface cleaning and protection from corrosion and other damages.

Mercaptoacetic Acid is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Mercaptoacetic Acid is used in the following products: cosmetics and personal care products.
Other release to the environment of Mercaptoacetic Acid is likely to occur from: indoor use as processing aid.

Mercaptoacetic Acid is used in the following products: laboratory chemicals and cosmetics and personal care products.
Mercaptoacetic Acid is used in the following areas: scientific research and development.
Other release to the environment of Mercaptoacetic Acid is likely to occur from: indoor use as reactive substance and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).

Mercaptoacetic Acid is used in the following products: leather treatment products and cosmetics and personal care products.
Mercaptoacetic Acid has an industrial use resulting in manufacture of another substance (use of intermediates).
Release to the environment of Mercaptoacetic Acid can occur from industrial use: formulation of mixtures.

Mercaptoacetic Acid is used in the following products: oil and gas exploration or production products.
Mercaptoacetic Acid has an industrial use resulting in manufacture of another substance (use of intermediates).
Mercaptoacetic Acid is used in the following areas: mining and scientific research and development.

Mercaptoacetic Acid is used for the manufacture of: chemicals.
Release to the environment of Mercaptoacetic Acid can occur from industrial use: of substances in closed systems with minimal release, in processing aids at industrial sites and as an intermediate step in further manufacturing of another substance (use of intermediates).

Release to the environment of Mercaptoacetic Acid can occur from industrial use: manufacturing of the substance.
Mercaptoacetic Acid is used as a chemical depilatory and is still used as such, especially in salt forms, including calcium thioglycolate and sodium thioglycolate.

Mercaptoacetic Acid is the precursor to ammonium thioglycolate that is used for permanents.
Mercaptoacetic Acid is also used as an acidity indicator, manufacturing of thioglycolates, and in bacteriology for preparation of thioglycolate media.
In fact thioglycolysis reactions used on condensed tannins to study their structure.

Cosmetic Industry: Active ingredient in depilatory creams and hair perming solutions due to Mercaptoacetic Acid's ability to break disulfide bonds in keratin.
Metal Treatment: Mercaptoacetic Acid is utilized in metal cleaning and electroplating solutions to improve surface quality.

Pharmaceuticals uses of Mercaptoacetic Acid: Precursor in the synthesis of certain drugs and active pharmaceutical ingredients (APIs).
Polymer Industry uses of Mercaptoacetic Acid: Chain transfer agent in the polymerization of vinyl chloride and other monomers.
Analytical Chemistry uses of Mercaptoacetic Acid: Chelating agent for metal ions, especially in spectroscopic analysis.

Mercaptoacetic Acid is widely used in the hairdressing industry, which mostly caters to women.
Mercaptoacetic Acid is used to manufacture drugs, permanent wave solutions, and other chemicals; Concentrations are up to 11% in hair products and 5% in depilatories.

-Cosmetics uses of Mercaptoacetic Acid:
The salts of Mercaptoacetic Acid and also some of its esters are used in the formulation of perms and for the preparation of depilatory creams.
In these applications, the main salts are ammonium thioglycolate and potassium thioglycolate.
In some areas, glycerol monothioglycolate is also used.

-Oil and Gas uses of Mercaptoacetic Acid:
Mercaptoacetic Acid is used in several areas of the Oil and Gas industry:
*As a reducing and chelating agent to limit Fe3+ precipitation during well drilling or stimulation.

*For the oil refining, Mercaptoacetic Acid mercaptides act as passivating agents during the catalytic cracking of hydrocarbons to limit the contamination of metal catalysts (Ni, V, etc.)

*Mercaptoacetic Acid is also used as an additive in corrosion inhibiting formulations to protect the equipment.
Corrosion inhibitors are injected either continuously into the fluid stream or into a producing well.

-Polymerization uses of Mercaptoacetic Acid:
Mercaptoacetic Acid is a very effective chain transfer agent for emulsion polymerizations in aqueous media, in particular for acrylic acid and acrylates.
The total miscibility of Mercaptoacetic Acid with water is a benefit in this application.

-Mining & Metal treatment uses of Mercaptoacetic Acid:
Mercaptoacetic Acid and its derivatives are also used as depressant agents in flotation processes for separating valuable metals from ores in mining operations.
Mercaptoacetic Acid derivatives are a safer alternative to the more traditional sodium sulfhydrate (NaSH), particularly in mining environments.

-Chemical Industry use of Mercaptoacetic Acid:
Mercaptoacetic Acid is used as a reducing agent in chemical syntheses.
Mercaptoacetic Acid is used intermediate in the production of esters and salts for various applications.

KEY BENEFITS OF MERCAPTOACETIC ACID:
*A polar and dual functional (-SH & -COOH) mercaptan
*Fully water soluble
*Colorless and liquid
*A strong reducing agent especially at high pH
*A powerful complexing/chelating agent
*A good nucleophilic agent

ALTERNATIVE PARENTS OF MERCAPTOACETIC ACID:
*Monocarboxylic acids and derivatives
*Alkylthiols
*Organic oxides
*Hydrocarbon derivatives
*Carbonyl compounds

SUBSTITUENTS OF MERCAPTOACETIC ACID:
*2-mercaptocarboxylic acid
*Monocarboxylic acid or derivatives
*Alkylthiol
*Organic oxygen compound
*Organic oxide
*Hydrocarbon derivative
*Organosulfur compound
*Organooxygen compound
*Carbonyl group
*Aliphatic acyclic compound

PROPERTIES AND BENEFITS OF MERCAPTOACETIC ACID:
*Strong Reducing Properties:
Makes Mercaptoacetic Acid useful in oxidation-reduction reactions.

*Keratin Bond Breaker:
Effective in applications requiring protein structure modification, such as hair treatments.

*High Reactivity:
Mercaptoacetic Acid facilitates a wide range of chemical transformations.

*Metal Binding Ability:
Mercaptoacetic Acid enhances its utility as a chelating and cleaning agent.

STORAGE OF MERCAPTOACETIC ACID:
Store Mercaptoacetic Acid in a tightly closed container in a cool, dry, well-ventilated area.
Keep Mercaptoacetic Acid away from heat, sparks, and oxidizing agents.

PRODUCTION OF MERCAPTOACETIC ACID:
Mercaptoacetic Acid is prepared by reaction of sodium or potassium chloroacetate with alkali metal hydrosulfide in aqueous medium.
Mercaptoacetic Acid can be also prepared via the Bunte salt obtained by reaction of sodium thiosulfate with chloroacetic acid:

ClCH2CO2H + Na2S2O3 → Na[O3S2CH2CO2H] + NaCl
Na[O3S2CH2CO2H] + H2O → HSCH2CO2H + NaHSO4

REACTIONS OF MERCAPTOACETIC ACID:
Mercaptoacetic Acid with a pKa of 3.83 is an acid about 8.5 times stronger than acetic acid (pKa 4.76):
HSCH2CO2H → HSCH2CO2− + H+
The second ionization has a pKa of 9.3:

HSCH2CO2− → −SCH2CO2− + H+
Mercaptoacetic Acid is a reducing agent, especially at higher pH.

Mercaptoacetic Acid oxidizes to the corresponding disulfide (2-[(carboxymethyl)disulfanyl]acetic acid or dithiodiglycolic acid):
2 HSCH2CO2H + "O" → [SCH2CO2H]2 + H2O

**With metal ions
Mercaptoacetic Acid, usually as its dianion, forms complexes with metal ions.
Such complexes have been used for the detection of iron, molybdenum, silver, and tin.
Mercaptoacetic Acid reacts with diethyl acetylmalonate to form acetylmercaptoacetic acid and diethyl malonate, the reducing agent in the conversion of Fe(III) to Fe(II).

HISTORY OF MERCAPTOACETIC ACID:
Scientist David R. Goddard, in the early 1930s, identified Mercaptoacetic Acid as a useful reagent for reducing the disulfide bonds in proteins, including keratin (hair protein), while studying why protease enzymes could not easily digest hair, nails, feathers, and such.

He realized that while the disulfide bonds, which stabilize proteins by cross-linking, were broken, the structures containing these proteins could be reshaped easily, and that they would retain this shape after the disulfide bonds were allowed to re-form.
Mercaptoacetic Acid was developed in the 1940s for use as a chemical depilatory.

PHYSICAL and CHEMICAL PROPERTIES of MERCAPTOACETIC ACID:
Chemical formula: C2H4O2S
Molar mass: 92.11 g·mol−1
Appearance: colorless, clear liquid
Odor: strong, disagreeable
Density: 1.32 g/cm3
Melting point: −16 °C (3 °F; 257 K)
Boiling point: 96 °C (205 °F; 369 K) at 5 mmHg
Solubility in water: miscible
Vapor pressure: 10 mmHg (17.8 °C)
Magnetic susceptibility (χ): −50.0·10−6 cm3/mol
Molecular Weight: 92.12 g/mol
XLogP3: 0.1
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 1

Exact Mass: 91.99320054 Da
Monoisotopic Mass: 91.99320054 Da
Topological Polar Surface Area: 38.3Å²
Heavy Atom Count: 5
Formal Charge: 0
Complexity: 42.9
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1

Compound Is Canonicalized: Yes
Physical description: Colorless liquid with a strong,
disagreeable odor characteristic of mercaptans.
Boiling point: 248°F at 20 mmHg
Molecular weight: 92.12
Freezing point/melting point: 2.3°F
Vapor pressure: 10 mmHg at 64°F
Flash point: 235°F
Vapor density:
Specific gravity: 1.33
Ionization potential:
Lower explosive limit (LEL): 5.9%

CAS: 68-11-1
Molecular Formula: C2H4O2S
Molecular Weight (g/mol): 92.112
MDL Number: MFCD00004876
InChI Key: CWERGRDVMFNCDR-UHFFFAOYSA-N
ChEBI: CHEBI:30065
IUPAC Name: 2-sulfanylacetic acid
SMILES: C(C(=O)O)S
Chemical formula: C2H4O2S
Molar mass: 92.11 g·mol−1
Appearance: colorless, clear liquid
Odor: strong, disagreeable
Density: 1.32 g/cm3
Melting point: −16 °C (3 °F; 257 K)

Boiling point: 96 °C (205 °F; 369 K) at 5 mmHg
Solubility in water: miscible
Vapor pressure: 10 mmHg (17.8 °C)
Magnetic susceptibility (χ): −50.0·10−6 cm3/mol
CAS number: 68-11-1
EC index number: 607-090-00-6
EC number: 200-677-4
Grade: Reag. Ph Eur
Hill Formula: C₂H₄O₂S
Chemical formula: HSCH₂COOH
Molar Mass: 92.12 g/mol
HS Code: 2930 90 98

Boiling point: 220 °C (1013 hPa) (decomposition)
Density: 1.325 g/cm3
Flash point: 130 °C
Melting Point: -16 °C
pH value: 1.5 (10 g/l, H₂O, 20 °C)
Vapor pressure: 0.5 hPa (25 °C)
Physical state: liquid
Color: colorless
Odor: Stench.
Melting point/freezing point:
Melting point/range: -16 °C
Initial boiling point and boiling range: 96 °C at 7 hPa
Flammability (solid, gas): No data available

Upper/lower flammability or explosive limits:
Lower explosion limit: 5,9 %(V)
Flash point: 130 °C - closed cup
Autoignition temperature: 315 °C at 1.020 hPa
Decomposition temperature: No data available
pH: 1,5 at 10 g/l at 20 °C
Viscosity
Viscosity, kinematic: 4,69 mm2/s at 20 °C
Viscosity, dynamic: 6,55 mPa.s at 20 °C
Water solubility: 1.000 g/l at 20 °C - completely soluble
Partition coefficient: n-octanol/water:
log Pow: -2,99 at 22 °C - Bioaccumulation is not expected.
Vapor pressure: 0,5 hPa at 25 °C
Density: 1,325 g/cm3

Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information:
Relative vapor density: 3,18 - (Air = 1.0)
CBNumber:CB6477604
Molecular Formula:C2H4O2S
Molecular Weight:92.12
MDL Number:MFCD00004876

MOL File:68-11-1.mol
Melting point: −16 °C(lit.)
Boiling point: 96 °C5 mm Hg(lit.)
Density: 1.326 g/mL at 20 °C(lit.)
vapor density: 3.2 (vs air)
vapor pressure: 0.4 mm Hg ( 25 °C)
refractive index: n20/D 1.505(lit.)
Flash point: 126 °C
storage temp.: Store at +2°C to +8°C.
solubility: Chloroform (Sparingly), Methanol (Sparingly)
form: Liquid
pka: 3.68(at 25℃)

color: clear clear, colorless
Odor: strong unpleasant odor
PH: 1 (H2O, 20℃)
Water Solubility: soluble
Sensitive: Air Sensitive
Merck: 14,9336
BRN: 506166
Exposure limits TLV-TWA: 1 ppm (～3.8 mg/m3) (ACGIH).
Stability: Air Sensitive
InChIKey: CWERGRDVMFNCDR-UHFFFAOYSA-N
LogP: 0.090

CAS DataBase Reference: 68-11-1(CAS DataBase Reference)
EWG's Food Scores: 3-5
FDA UNII: 7857H94KHM
NIST Chemistry Reference: Acetic acid, mercapto-(68-11-1)
EPA Substance Registry System: Thioglycolic acid (68-11-1)
Molecular Weight: 92.12 g/mol
XLogP3: 0.1
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 1

Exact Mass: 91.99320054 g/mol
Monoisotopic Mass: 91.99320054 g/mol
Topological Polar Surface Area: 38.3Å²
Heavy Atom Count: 5
Formal Charge: 0
Complexity: 42.9
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Appearance: Clear colorless Liquid
Infrared spectrum: Conforms
Refractive index: 1.5030 to 1.5050 (20°C, 589 nm)
Titration Iodimetric: ≥97.5 %
Iron (Fe): ≤300 ppb

Impurity: ≤0.2 % Other acids (as TGA)
UV: at 350 nm A: ≤0.01
UV: at 450 nm A: ≤0.01
UV: 1 cm cell vs water
Color scale: ≤10 APHA
Residue after evaporation: ≤0.001 %
Acidity: ≤0.0003 meq/g
Formula: HSCH₂COOH
MW: 92.12 g/mol
Boiling Pt: 220 °C (760 mmHg)
Melting Pt: –16 °C
Density: 1.325 g/cm³
Flash Pt: 126 °C

Storage Temperature: Refrigerator
MDL Number: MFCD00004876
CAS Number: 68-11-1
EINECS: 200-677-4
UN: 1940
ADR: 8,II
Merck Index: 12,09472
Molecular Weight：
92.11700
Exact Mass： 92.12
EC Number： 200-677-4
HScode： 2930909090

PSA：76.10000
XLogP3：0.00080
Appearance：: Thioglycolic acid appears as a
colorless liquid with an unpleasant odor.
Density: 1.325 g / cm3.
Density：1.3253 g/cm3 @ Temp: 20 °C
Melting Point：-16.5 °C
Boiling Point：120 °C @ Press: 20 Torr
Flash Point：126ºC
Refractive Index：1.503-1.505

Water Solubility：H2O: soluble
Storage Conditions：2-8ºC
Vapor Pressure：0.4 mm Hg ( 25 °C)
Vapor Density：3.2 (vs air)
Odor：Strong, unpleasant odor
CAS: 68-11-1
EINECS: 200-677-4
InChI: InChI=1/C2H4O2S/c3-2(4)1-5/h5H,1H2,(H,3,4)/p-1
InChIKey: CWERGRDVMFNCDR-UHFFFAOYSA-N
Molecular Formula: C2H4O2S

Molar Mass: 92.12
Density: 1.326g/mLat 20°C(lit.)
Melting Point: −16°C(lit.)
Boling Point: 96°C5mm Hg(lit.)
Flash Point: 126 °C
Water Solubility: soluble
Vapor Presure: 0.4 mm Hg ( 25 °C)
Vapor Density: 3.2 (vs air)
Appearance: Liquid
Color: clear clear, colorless

Exposure Limit: TLV-TWA 1 ppm (～3.8 mg/m3) (ACGIH).
Merck: 14,9336
BRN: 506166
pKa: 3.68(at 25℃)
PH: 1 (H2O, 20℃)
Storage Condition: Store at +2°C to +8°C.
Sensitive: Air Sensitive
Refractive Index: n20/D 1.505(lit.)
Physical and Chemical Properties:
The pure product is a colorless transparent liquid,
and the industrial product is colorless to yellowish.

melting point: -16.5 ℃
boiling point: 123 ℃
relative density: 1.3253
refractive index: 1.5030
BR> solubility and water, ethanol and ether are miscible.
Chemical Formula: C2H4O2S
Average Molecular Weight: 92.117
Monoisotopic Molecular Weight: 91.993200062
IUPAC Name: 2-sulfanylacetic acid
Traditional Name: thioglycolic acid
CAS Registry Number: Not Available
SMILES: OC(=O)CS

InChI Identifier: InChI=1S/C2H4O2S/c3-2(4)1-5/h5H,1H2,(H,3,4)
InChI Key: CWERGRDVMFNCDR-UHFFFAOYSA-N
Pharmacodynamics: Not Available
Mechanism of action: Not Available
Absorption: Not Available
Volume of distribution: Not Available
Protein binding: Not Available
Metabolism: Not Available
Route of elimination: Not Available
Half-life: Not Available
Clearance: Not Available

CAS: 68-11-1
Molecular Formula: C2H4O2S
Molecular Weight: 92.12
Storage Details: 2 to 8 °C
Harmonised Tariff Code: 2930909899
Chemical Formula: C2H4O2S
Average Molecular Weight: 92.117
Monoisotopic Molecular Weight: 91.993200062
IUPAC Name: 2-sulfanylacetic acid
Traditional Name: thioglycolic acid

CAS Registry Number: Not Available
SMILES: OC(=O)CS
InChI Identifier: InChI=1S/C2H4O2S/c3-2(4)1-5/h5H,1H2,(H,3,4)
InChI Key: CWERGRDVMFNCDR-UHFFFAOYSA-N
Molecular form: C2H4O2S
Appearance: Clear Colourless Oil
Mol. Weight: 92.12
Storage: 2-8°C Refrigerator, Under Inert Atmosphere
Shipping Conditions: Ambient
Applications: NA

FIRST AID MEASURES of MERCAPTOACETIC ACID:
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available

ACCIDENTAL RELEASE MEASURES of MERCAPTOACETIC ACID:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully with liquid-absorbent material.
Dispose of properly.
Clean up affected area.

FIRE FIGHTING MEASURES of MERCAPTOACETIC ACID:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system

EXPOSURE CONTROLS/PERSONAL PROTECTION of MERCAPTOACETIC ACID:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Chloroprene
Minimum layer thickness: 0,65 mm
Break through time: 480 min
Splash contact:
Material: Latex gloves
Minimum layer thickness: 0,6 mm
Break through time: 120 min
*Body Protection:
Acid-resistant protective clothing
*Respiratory protection:
Recommended Filter type: Respirator.
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of MERCAPTOACETIC ACID:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities
*Storage conditions
Tightly closed.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
*Storage stability:
Recommended storage temperature:
2 - 8 °C

STABILITY and REACTIVITY of MERCAPTOACETIC ACID:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .