TRIPROPYLAMINE
Tripropylamine is an organic compound with the formula (CH3CH2CH2)3N.
Tripropylamine is classified as a tertiary amine.
Tripropylamine is a colorless liquid with a "fishy" odor.
CAS: 102-69-2
European Community (EC) Number: 203-047-7
IUPAC Name: N,N-dipropylpropan-1-amine
Molecular Weight: 143.27 g/mol
Molecular Formula: C9H21N
TRIPROPYLAMINE, Tri-n-propylamine, 102-69-2, 1-Propanamine, N,N-dipropyl-, N,N-dipropylpropan-1-amine, N,N-Dipropyl-1-propanamine, Propyldi-n-propylamine, Tripropylammonium, NPr3, N,N-Dipropyl-1-propylamine, (n-C3H7)3N, 06S624V3U2, Tripropylamine, >=98%, Tripropyl amine, HSDB 2097, EINECS 203-047-7, UN2260, UNII-06S624V3U2, tri-n-propyl amin, tri(n-propyl)amine, tri-n-propyl-amine, MFCD00009363, tris(1-propyl)amine, Tripropylamine [UN2260] [Flammable liquid], N,N-Dpropyl-1-propanamne, EC 203-047-7, SCHEMBL5358, NCIOpen2_001723, TRIPROPYLAMINE [FHFI], TRIPROPYLAMINE [HSDB], DTXSID9021849, FEMA NO. 4247, CHEBI:38880, Tripropylamine, analytical standard, AKOS000120960, UN 2260, NS00004814, T0522, Tripropylamine [UN2260] [Flammable liquid], J-000767, J-523283, Q1637944, InChI=1/C9H21N/c1-4-7-10(8-5-2)9-6-3/h4-9H2,1-3H
Tripropylamine is a tertiary amine which belongs to the class of trialkylamines.
The main application for Tripropylamine is the production of quats, which are used as phase transfer catalyst.
Smaller volumes are used as proton scavenger or as molecular template in the production of microporous inorganic catalysts.
Tripropylamine is a tertiary amine that is ammonia in which each hydrogen atom is substituted by a propyl group.
Tripropylamine appears as a water-white liquid.
Flash point near 125 °F.
Less dense than water.
Tripropylamine is used as a solvent.
Tripropylamine was employed as coreactant in sandwich-type electrochemiluminescence biosensor for detection of α-fetoprotein.
Tripropylamine was used as extraction agent for the reactive extraction of succinic acid in various alcohol diluents.
Tripropylamine, also known as (N-C3H7)3N or NPR3, belongs to the class of organic compounds known as trialkylamines.
These are organic compounds containing a trialkylamine group, characterized by exactly three alkyl groups bonded to the amino nitrogen.
Based on a literature review a significant number of articles have been published on Tripropylamine.
Tripropylamine (TPA) is an organic compound having the molecular formula C3H9N.
Classified as an amine, which is a type of organic compound characterized by a fundamental nitrogen atom bearing a pair of unshared electrons, Tripropylamine presents as a colorless liquid emitting a potent ammonia-like fragrance.
This liquid substance readily mixes with water, finding utility across a range of laboratory contexts and organic synthesis procedures.
The versatile nature of tripropylamine finds application within scientific research realms.
Employed as a catalyst, Tripropylamine facilitates the construction of organic compounds; as a reagent, it aids in pharmaceutical production; and it serves as an enzyme stabilizer.
Additionally, Tripropylamine's role extends to polymer synthesis, chromatography solvent, and the formulation of dyes and pigments.
Tripropylamine assumes the role of a proton contributor, bestowing a proton upon molecules or ions, thereby engendering novel molecules or ions.
This mechanism governs numerous chemical reactions, inclusive of amide and amine formation, alongside the genesis of organometallic complexes.
Tripropylamine is an organic compound that belongs to the group of alkylamines.
Tripropylamine has a phase transition temperature at -37 °C and can be used as a reagent in chemical synthesis, as well as an intermediate for the production of other compounds.
Tripropylamine can be detected by electrochemical impedance spectroscopy (EIS) with a detection sensitivity of 0.5 ppm.
Kinetic data for tripropylamine was obtained using methyl ethyl ketone and hydrogen fluoride, which yielded k(M) = 1.2 x 10^-3 and k(S) = 2.4 x 10^-2 M-1s-1 respectively.
The reaction mechanism for tripropylamine involves the formation of picolinic acid from 3-hydroxypropionic acid and ammonia, followed by decarboxylation to form picolinic acid.
Tripropylamine (TPA) is a tertiary amine which belongs to the class of trialkylamines.
Main application for Tripropylamine are the production of quats (phase transfer catalyst) and is used as proton scavenger or as molecular template in the production of catalysts.
The Tripropylamine molecule consists of 21 Hydrogen atom(s), 9 Carbon atom(s), and 1 Nitrogen atom(s) - a total of 31 atom(s).
The molecular weight of Tripropylamine is determined by the sum of the atomic weights of each constituent element multiplied by the number of atoms, which is calculated to be:
143.26974⋅gmol
The exact term of the above molecular weight is “molar mass”, which is based on the atomic mass of each element.
Molecular weight is actually an older term of “relative molar mass” or “molecular mass”, which is a dimensionless quantity equal to the molar mass divided by the molar mass constant defined by 1 g/mol.
Molecular masses are calculated from the standard atomic weights of each nuclide, while molar masses are calculated from the atomic mass of each element.
The atomic mass takes into account the isotopic distribution of the element in a given sample.
Tripropylamine (according to IUPAC nomenclature : N,N -dipropylpropan-1-amine , also tri -n -propylamine) is an organic chemical compound from the group of tertiary aliphatic amines .
The large-scale production of tripropylamine follows a two-stage process. First, n -propanol is reacted with ammonia in the gas phase over a copper- or nickel-containing heterogeneous catalyst at temperatures of 130 to 250 °C and pressures generally of 1 to 220 bar to form a product mixture of mono- , di- and tripropylamine.
In the next step, this is separated by multi-stage distillation and the tri- n -propylamine that has already formed is removed.
The remaining di -n -propylamine is then converted in a second reactor, on a copper or nickel catalyst supported with aluminum and zirconium(IV) oxide, at temperatures of 200 to 260 °C and pressures of 60 to 150 bar to tri -n -propylamine and ammonia.
Unreacted n -propanol, ammonia and monopropylamine are returned to the first reaction stage.
The reactors used are usually tube bundle reactors with a circulating gas flow and a fixed bed, in which molten salts keep the reaction at an almost constant temperature.
Tripropylamine is an organic compound with the formula (CH3CH2CH2)3N.
Tripropylamine is classified as a tertiary amine.
Tripropylamine is a colorless liquid with a "fishy" odor.
Tripropylamine was employed as coreactant in sandwich-type electrochemiluminescence biosensor for detection of α-fetoprotein.
Tripropylamine was used as extraction agent for the reactive extraction of succinic acid in various alcohol diluents.
Tripropylamine, also known as (N-C3H7)3N or NPR3, belongs to the class of organic compounds known as trialkylamines.
These are organic compounds containing a trialkylamine group, characterized by exactly three alkyl groups bonded to the amino nitrogen.
Based on a literature review a significant number of articles have been published on Tripropylamine.
Physical Properties
Chemical Formula: C9H21N
Flash Point: 98°F
Lower Explosive Limit (LEL): 0.7 %
Upper Explosive Limit (UEL): 5.6 %
Autoignition Temperature: 356°F
Melting Point: -136.3°F
Vapor Pressure: less than 1 mmHg at 68°F
Vapor Density (Relative to Air): 4.9 - Heavier than air; will sink
Specific Gravity: 0.754 at 68°F - Less dense than water; will float
Boiling Point: 313°F at 760 mmHg
Molecular Weight: 143.27
Water Solubility: less than 1 mg/mL at 66°F
Properties
Physical properties
Tripropylamine has a relative gas density of 4.94 (density ratio to dry air at the same temperature and pressure ) and a relative density of the vapor-air mixture of 1.01 (density ratio to dry air at 20 °C and normal pressure ). Tripropylamine also has a vapor pressure of 4.30 hPa at 20 °C. [1]
Chemical properties
Tripropylamine is a flammable, colorless liquid from the group of aliphatic tertiary amines.
Tripropylamine is very sparingly soluble in water (0.75 g·l −1 at 25 °C) and lighter than water.
Tripropylamine is sparingly or very volatile.
When heated in air, Tripropylamine decomposes to form toxic nitrosamines and can react dangerously with strong oxidizing agents, acids, hydrogen peroxide, oxidizing substances, chlorinated hydrocarbons, nitriles, oxides, peroxides and phenols.
At 20 °C, an aqueous solution of 2.6 g/l has a pH of 11.4.
Usage
Tripropylamine (TPA) is an important chemical intermediate for the production of dyes, catalysts and corrosion inhibitors.
Tripropylamine is also used in the pharmaceutical and cosmetics industries.
Tripropylamine has also proven to be useful for the production of quats, which are used as phase transfer catalysts .
Industries & Applications
Agriculture:
- Pest Control
- Pest Control / Any Pest Control Applications
Chemicals:
- Intermediates
Pharmaceuticals:
- (Pharma) APIs & Raw Materials, APIs & Raw Materials
Healthcare & Pharmaceuticals:
- APIs & Raw Materials / Any APIs & Raw Materials Applications
Tripropylamine - Nature
colorless transparent flammable liquid, ammonia odor.
Soluble in ethanol, soluble in ether, water-soluble.
The relative density was 0.7558.
Boiling point 156 °c.
Melting Point -93.5 °c.
Flash point 40.55 °c (Open Cup).
Refractive index 4181.
Tripropylamine - Preparation Method
With N-propanol as raw material under the action of Ni-CLi-Al2 03 catalyst, dehydrogenation generates propanal, and then with ammonia addition, dehydration, hydrogenation to produce propylamine, and then by repeated dehydration, hydrogenation to produce dipropylamine and tripropylamine.
The reaction temperature was (210±10)℃, the pressure was 396.66kPa, and the space velocity of N-propanol was 0.25-0.51L/L.h-I.
The raw material ratio is alcohol: Ammonia: hydrogen -4:2:4.
The conversion of N-propanol is 75% ~ 83%, and the total yield of di-and tripropylamine is 75% ~ 80%, in which dipropylamine is 37% ~ 41% and tripropylamine is 35% ~ 40%.
Tripropylamine - Use
Tripropylamine is a raw material for organic synthesis, can be used for the synthesis of perfluorinated artificial plasma and petrochemical quaternary ammonium molecular sieve catalyst, this product also has important uses in laser technology.
Applications:
Tripropylamine is used for raw materials of organic synthesis such as pharmaceuticals, pesticides, rubber and fiber processing aids.
For the synthesis of perfluorinated artificial plasma and petrochemical quaternary ammonium molecular sieve catalyst.
Tripropylamine also has important applications in laser technology.
Tripropylamine is an organic synthesis intermediate for the preparation of perfluorinated artificial plasma and petrochemical quaternary ammonium molecular sieve catalysts.
Tripropylamine is used in the manufacture of pharmaceuticals, pesticides, rubber and fiber processing aids.
Tripropylamine is used for the synthesis of perfluorinated artificial plasma and petrochemical quaternary ammonium molecular sieve catalysts.
Raw materials for organic synthesis, synthesis of perfluorinated artificial plasma and petrochemical quaternary ammonium molecular sieve catalysts.
Tripropylamine also has important applications in laser technology.
Tripropylamine was employed as coreactant in sandwich-type electrochemiluminescence biosensor for detection of α-fetoprotein.
Tripropylamine was used as extraction agent for the reactive extraction of succinic acid in various alcohol diluents.